Zobrazeno 1 - 10
of 548
pro vyhledávání: '"James A, Bonner"'
Autor:
Hongxing Shen, Oluwagbemiga A. Ojo, Haitao Ding, Logan J. Mullen, Chuan Xing, M. Iqbal Hossain, Abdelrahman Yassin, Vivian Y. Shi, Zach Lewis, Ewa Podgorska, Shaida A. Andrabi, Maciek R. Antoniewicz, James A. Bonner, Lewis Zhichang Shi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Hypoxia is a common feature in various pathophysiological contexts, including tumor microenvironment, and IFN-γ is instrumental for anti-tumor immunity. HIF1α has long been known as a primary regulator of cellular adaptive responses to hyp
Externí odkaz:
https://doaj.org/article/17a66108966a4d25bc8186281738e71b
Autor:
Ho Young Lee, Dorothy J. You, Alexia Taylor-Just, Logan J. Tisch, Ryan D. Bartone, Hannah M. Atkins, Lauren M. Ralph, Silvio Antoniak, James C. Bonner
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) has been reported to exert strong pro-inflammatory and pro-fibrotic adjuvant effects in mouse models of allergic lung disease. However, the molecular mechanisms through
Externí odkaz:
https://doaj.org/article/32e1e4ddbe73477b8a60b356f6b92171
Autor:
Joseph A. Jones, MD, Michael H. Soike, MD, D. Hunter Boggs, MD, John B. Fiveash, MD, Rex A. Cardan, PhD, James A. Bonner, MD, Andrew M. McDonald, MD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 4, Pp 101218- (2023)
Purpose: The aim of this work was to describe the design and implementation of a more robust workflow for communicating outcomes from a peer-review chart rounds conference. We also provide information regarding cycle times, plan revisions, and other
Externí odkaz:
https://doaj.org/article/d02fef5dd2f4462186ea7ba2e09fa7f1
Autor:
Ruby F. Meredith, MD, PhD, John R. Bassler, MS, Andrew M. McDonald, MD, John M. Stahl, MD, David T. Redden, PhD, James A. Bonner, MD
Publikováno v:
Advances in Radiation Oncology, Vol 8, Iss 4, Pp 101214- (2023)
Purpose: Various radiation therapy (RT) dose/fractionation schedules are acceptable for palliation in multiple myeloma. Nine years of single-institution RT experience were reviewed to determine the influence of dose/fractionation and other factors pe
Externí odkaz:
https://doaj.org/article/62b9e9395c554974a6385a9fb2c0d0fc
Autor:
Hongxing Shen, Fengyuan Huang, Xiangmin Zhang, Oluwagbemiga A. Ojo, Yuebin Li, Hoa Quang Trummell, Joshua C. Anderson, John Fiveash, Markus Bredel, Eddy S. Yang, Christopher D. Willey, Zechen Chong, James A. Bonner, Lewis Zhichang Shi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Tumor loss of IFN-γ signalling is a major mechanism of resistance to immune checkpoint blockers. Here the authors report that melanoma cells with knockout of IFNγR1 show constitutive JAK1/2 activation and that the JAK1/2 inhibitor ruxolitinib can o
Externí odkaz:
https://doaj.org/article/d38ce33d0e5a4670b226973e3a573576
Autor:
Dominique Lison, Saloua Ibouraadaten, Sybille van den Brule, Milica Todea, Adriana Vulpoi, Flaviu Turcu, Christina Ziemann, Otto Creutzenberg, James C. Bonner, Marcel Ameloot, Hannelore Bové
Publikováno v:
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background In vitro models are widely used in nanotoxicology. In these assays, a careful documentation of the fraction of nanomaterials that reaches the cells, i.e. the in vitro delivered dose, is a critical element for the interpretation of
Externí odkaz:
https://doaj.org/article/36fa8f8752c94e0a9ad2b5ee485b930d
Autor:
Alexia J. Taylor-Just, Mark D. Ihrie, Katherine S. Duke, Ho Young Lee, Dorothy J. You, Salik Hussain, Vamsi K. Kodali, Christina Ziemann, Otto Creutzenberg, Adriana Vulpoi, Flaviu Turcu, Monica Potara, Milica Todea, Sybille van den Brule, Dominique Lison, James C. Bonner
Publikováno v:
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Inhalation of multi-walled carbon nanotubes (MWCNTs) poses a potential risk to human health. In order to safeguard workers and consumers, the toxic properties of MWCNTs need to be identified. Functionalization has been shown to ei
Externí odkaz:
https://doaj.org/article/f5fdca8869504a2db332be4a4099eecb
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 2, Pp 267-269 (2020)
Externí odkaz:
https://doaj.org/article/18ca9906222647b6b6a0b4ed1bc21760
Autor:
Ling Zeng, Drexell Hunter Boggs, Chuan Xing, Zhuo Zhang, Joshua C. Anderson, Narendra Wajapeyee, Chris Veale, Markus Bredel, Lewis Z. Shi, James A. Bonner, Christopher D. Willey, Eddy S. Yang
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Novel targeted agents to inhibit DNA repair pathways to sensitize tumors to irradiation (IR) are being investigated as an alternative to chemoradiation for locally advanced human papilloma virus negative (HPV-negative) head and neck squamous cell car
Externí odkaz:
https://doaj.org/article/f716021e1f6549fb9da39a8bff8d3bda
Autor:
Sindhu Nair, Hoa Q Trummell, Rajani Rajbhandari, Nanda K Thudi, Susan E Nozell, Jason M Warram, Christopher D Willey, Eddy S Yang, William J Placzek, James A Bonner, Markus Bredel
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229077 (2020)
Epidermal growth factor receptor (EGFR) is a pro-tumorigenic receptor tyrosine kinase that facilitates growth for cancer cells that overexpress the receptor. Monoclonal anti-EGFR antibody Cetuximab (CTX) provides significant clinical benefit in patie
Externí odkaz:
https://doaj.org/article/20ddfc5b974349a48705b8719e140d9b