Zobrazeno 1 - 3
of 3
pro vyhledávání: '"James Pivnichny"'
Autor:
Linus S, Lin, Thomas, Lanza, James P, Jewell, Ping, Liu, Carrie, Jones, Gerard R, Kieczykowski, Kelly, Treonze, Qian, Si, Salony, Manior, Gloria, Koo, Xinchun, Tong, Junying, Wang, Anne, Schuelke, James, Pivnichny, Regina, Wang, Conrad, Raab, Stella, Vincent, Philip, Davies, Malcolm, Maccoss, Richard A, Mumford, William K, Hagmann
Publikováno v:
Journal of medicinal chemistry. 52(11)
Extremely potent very late antigen-4 (VLA-4) antagonists with picomolar, whole blood activity and slow dissociation rates were discovered by incorporating an amino substituent on the proline fragment of the initial lead structure. This level of poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9a6bbef5a020db297b6f1e1be61f223
https://pubmed.ncbi.nlm.nih.gov/19441819
https://pubmed.ncbi.nlm.nih.gov/19441819
Autor:
Judith E, Fenyk-Melody, Xiaolan, Shen, Qianping, Peng, William, Pikounis, Lawrence, Colwell, James, Pivnichny, Lynn C, Anderson, Constantin S, Tamvakopoulos
Publikováno v:
Comparative medicine. 54(4)
In the process of drug discovery, brain and plasma measurements of new chemical entities in rodents are of interest, particularly when the target receptors are in the brain. Brain-to-plasma ratios (B/P) obtained from a rodent pharmacokinetic assay ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::207a2bc8be4807b37fb88a3f0a532b62
https://pubmed.ncbi.nlm.nih.gov/15357317
https://pubmed.ncbi.nlm.nih.gov/15357317
Autor:
Linus S. Lin, Thomas Lanza, James P. Jewell, Ping Liu, Carrie Jones, Gerard R. Kieczykowski, Kelly Treonze, Qian Si, Salony Manior, Gloria Koo, Xinchun Tong, Junying Wang, Anne Schuelke, James Pivnichny, Regina Wang, Conrad Raab, Stella Vincent, Philip Davies, Malcolm MacCoss, Richard A. Mumford
Publikováno v:
Journal of Medicinal Chemistry; Jun2009, Vol. 52 Issue 11, p3449-3452, 4p