Zobrazeno 1 - 10
of 11
pro vyhledávání: '"James P. Sherbine"'
Autor:
Yue Tai-Yuen, James P. Sherbine, Jessica L. Defreese, Evan Barlow, Bao-Ning Su, Michael Peddicord, Monica A. Fitzgerald, Chris Sfouggatakis, Sévrine Broxer, Gerald L. Powers, Charles Pathirana
Publikováno v:
Organic Process Research & Development. 15:343-352
A scalable and robust process was developed for the preparation of pexacerfont (2), a pyrazolotriazine corticotropin-releasing factor receptor 1 antagonist (CRF1). The formation of the core hydroxy...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a99d6fe82e68eaeaa285fe06f1d1bd6
https://doi.org/10.1021/op100270u
https://doi.org/10.1021/op100270u
Autor:
Pingli Liu, James P. Sherbine, Patrick J. Sheeran, Stephen R. Anderson, Benjamin R. P. Stone, Jiang Zhu, Subodh Shrinivas Deshmukh, James J. Haley, Nicholas A. Magnus, Lindsay A. Hobson, William A. Nugent
Publikováno v:
Organic Process Research & Development. 11:985-995
This report describes the large-scale synthesis of 1 that features a Fischer indole strategy to form an advanced intermediate followed by reduction to the indoline to construct the tetracyclic core of the molecule. Resolution using dibenzoyl-d-tartar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393af969ac69807fc8425c2d159826f9
https://doi.org/10.1021/op700121y
https://doi.org/10.1021/op700121y
Autor:
Craig A. Shook, Manchao Xiao, James P. Sherbine, Theodore Cohen, Matthew L. Romberger, S.-H. Jung, Fu Tyan Lin, Birong Zhang
Publikováno v:
Journal of the American Chemical Society. 115:10754-10773
A variety of 1-(phenylthio)-1-(trimethylsilyl)cyclopropanes, fused to five-, six-, and seven-membered rings have been prepared by several procedures and reductively lithiated by means of aromatic radical anions. The resulting 1-lithio-1-(trimethylsil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e239a5470f21c85492dc0d9d2e0906d7
https://doi.org/10.1021/ja00076a037
https://doi.org/10.1021/ja00076a037
Autor:
Matthew L. Romberger, Theodore Cohen, Fu Tyan Lin, Manchao Xiao, S.-H. Jung, Birong Zhang, James P. Sherbine, Craig A. Shook
Publikováno v:
ChemInform. 25
A variety of 1-(phenylthio)-1-(trimethylsilyl)cyclopropanes, fused to five-, six-, and seven-membered rings have been prepared by several procedures and reductively lithiated by means of aromatic radical anions. The resulting 1-lithio-1-(trimethylsil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20296e993635f861ad3abe8c2f4b7f03
https://doi.org/10.1002/chin.199409075
https://doi.org/10.1002/chin.199409075
Autor:
David S. Teager, Neville L. Holder, Rodriguez Walter, Witold L. Tomasik, Philippe Pitchen, Benoit J. Vanasse, James P. Sherbine, Harshavadan C. Shah, David J. Taube, William L. Studt, Geoffrey A. D’Netto, Matthew R. Powers, Simon F. Golec, Anthony T. Gardetto, Woodward Rick G, Gregory C. Kubiak, Thompson Michael D, James J. Mencel, Vincent Windisch, Robert C. Liu, Diane C. Salazar, Adam W. Sledeski
Publikováno v:
Peptides for the New Millennium ISBN: 0792364457
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d22c9cd23c251a18e1f477a19f06a1
https://doi.org/10.1007/0-306-46881-6_51
https://doi.org/10.1007/0-306-46881-6_51
Autor:
Sévrine Broxer, Monica A. Fitzgerald, Chris Sfouggatakis, Jessica L. Defreese, Evan Barlow, Gerald L. Powers, Michael Peddicord, Bao-Ning Su, Yue Tai-Yuen, Charles Pathirana, James P. Sherbine
Publikováno v:
Organic Process Research & Development; Mar2011, Vol. 15 Issue 2, p343-352, 10p
Autor:
Lindsay A. Hobson, William A. Nugent, Stephen R. Anderson, Subodh S. Deshmukh, James J. Haley III, Pingli Liu, Nicholas A. Magnus, Patrick Sheeran, James P. Sherbine, Benjamin R. P. Stone, Jiang Zhu
Publikováno v:
Organic Process Research & Development; Oct2007, Vol. 11 Issue 6, p985-995, 11p
Publikováno v:
Tetrahedron Letters. 26:2965-2968
Two one flask connective methods for preparing 1-(phenylthio)-cyclopropylsilanes, precursors of 1-(lithio)cyclopropylsilanes, are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::907a110a58e64f8bcd3e904a1dbb61a0
https://doi.org/10.1016/s0040-4039(00)98593-9
https://doi.org/10.1016/s0040-4039(00)98593-9
Autor:
Barry M. McHenry, James R. Matz, Robert R. Hutchins, Paul R. Willey, Theodore Cohen, James P. Sherbine
Publikováno v:
Journal of the American Chemical Society. 106:3245-3252
On prepare des α-lithiosilanes par lithiation reductrice de diphenylthioacetals a l'aide du dimethylamino-1 naphtalenure de lithium, traitement de l'anion resultant par Me 3 SiCl et lithiation reductrice de l'α-(phenylthio) silane correspondant. La
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efff25d788d256d87c770d1a9e3f8440
https://doi.org/10.1021/ja00323a031
https://doi.org/10.1021/ja00323a031
Autor:
B. M. Mchenry, P. R. Willey, R. R. Hutchins, James P. Sherbine, James R. Matz, Theodore Cohen
Publikováno v:
Chemischer Informationsdienst. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3eaddd48d6485032404766987cf15dfd
https://doi.org/10.1002/chin.198436256
https://doi.org/10.1002/chin.198436256