Laser Capture and Deep Sequencing Reveals the Transcriptomic Programmes Regulating the Onset of Pancreas and Liver Differentiation in Human Embryos

Autor: Rachel E. Jennings, Andrew A. Berry, David T. Gerrard, Stephen J. Wearne, James Strutt, Sarah Withey, Mariya Chhatriwala, Karen Piper Hanley, Ludovic Vallier, Nicoletta Bobola, Neil A. Hanley

Publikováno v: Stem Cell Reports, Vol 9, Iss 5, Pp 1387-1394 (2017)

Summary: To interrogate the alternative fates of pancreas and liver in the earliest stages of human organogenesis, we developed laser capture, RNA amplification, and computational analysis of deep sequencing. Pancreas-enriched gene expression was les

Externí odkaz: https://doaj.org/article/3d0a79f8cb034b1f93e0306bdc437137

Mitchell-Riley syndrome iPSCs exhibit reduced pancreatic endoderm differentiation due to a mutation in

Autor: Jamie, Trott, Yunus, Alpagu, Ee Kim, Tan, Mohammad, Shboul, Yousif, Dawood, Michael, Elsy, Heike, Wollmann, Vincent, Tano, Carine, Bonnard, Shermaine, Eng, Gunaseelan, Narayanan, Seetanshu, Junnarkar, Stephen, Wearne, James, Strutt, Aakash, Kumar, Lucian B, Tomaz, Pierre-Alexis, Goy, Slim, Mzoughi, Rachel, Jennings, Jaco, Hagoort, Ascia, Eskin, Hane, Lee, Stanley F, Nelson, Fawaz, Al-Kazaleh, Mohammad, El-Khateeb, Rajaa, Fathallah, Harsha, Shah, Jonathan, Goeke, Sarah R, Langley, Ernesto, Guccione, Neil, Hanley, Bernadette S, De Bakker, Bruno, Reversade, N Ray, Dunn

Publikováno v: Development (Cambridge, England). 147(21)

Mitchell-Riley syndrome (MRS) is caused by recessive mutations in the regulatory factor X6 gene (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f977b2d81a6d953ebaae742dbb2a49d
https://pubmed.ncbi.nlm.nih.gov/33033118

Biochemical characterization of the tomato phosphatidylinositol-specific phospholipase C (PI-PLC) family and its role in plant immunity

Autor: Michael F. Seidl, Sara Dezhsetan, James Strutt, Matthieu H. A. J. Joosten, Jack H. Vossen, Arjan van Zeijl, Ahmed Abd-El-Haliem, Martina Beck, Christa Testerink, Silke Robatzek

Publikováno v: Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1861(9 Pt. B), 1365-1378. Elsevier
Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids, 1861(9 Part B), 1365-1378
Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids 1861 (2016) 9 Part B
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, Elsevier, 2016, 1861 (9), pp.1365-1378. ⟨10.1016/j.bbalip.2016.01.017⟩

International audience; Plants possess effective mechanisms to quickly respond to biotic and abiotic stresses. The rapid activation of phosphatidylinositol-specific phospholipase C (PLC) enzymes occurs early after the stimulation of plant immune-rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ed94a395ec9c1d4466097ac660ccc0
https://dare.uva.nl/personal/pure/en/publications/biochemical-characterization-of-the-tomato-phosphatidylinositolspecific-phospholipase-c-piplc-family-and-its-role-in-plant-immunity(196f5c50-4e36-4df7-b5c2-36a1c9db59fd).html