Zobrazeno 1 - 10
of 43
pro vyhledávání: '"James, Legg"'
Autor:
Luisa Chocarro, Ester Blanco, Leticia Fernandez-Rubio, Maider Garnica, Miren Zuazo, Maria Jesus Garcia, Ana Bocanegra, Miriam Echaide, Colette Johnston, Carolyn J Edwards, James Legg, Andrew J Pierce, Hugo Arasanz, Gonzalo Fernandez-Hinojal, Ruth Vera, Karina Ausin, Enrique Santamaria, Joaquin Fernandez-Irigoyen, Grazyna Kochan, David Escors
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 8, Pp 1791-1816 (2024)
Abstract Many cancer patients do not benefit from PD-L1/PD-1 blockade immunotherapies. PD-1 and LAG-3 co-upregulation in T-cells is one of the major mechanisms of resistance by establishing a highly dysfunctional state in T-cells. To identify shared
Externí odkaz:
https://doaj.org/article/28ff1b0ab6c0455fbce072272578f5f4
Autor:
Anna Kopp, Hyeyoung Kwon, Colette Johnston, Steven Vance, James Legg, Laurie Galson-Holt, Greg M. Thurber
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 48, Iss , Pp 100962- (2024)
Bispecific agents are a rapidly growing class of cancer therapeutics, and immune targeted bispecific agents have the potential to expand functionality well beyond monoclonal antibody agents. Humabodies⁎⁎ Humabody® is a registered trademark of Cr
Externí odkaz:
https://doaj.org/article/e10bbca475e14f86ac0602ed0855f6fb
Autor:
Yao Peng, Mary M. Dallas, José T. Ascencio-Ibáñez, J. Steen Hoyer, James Legg, Linda Hanley-Bowdoin, Bruce Grieve, Hujun Yin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Cassava brown streak disease (CBSD) is an emerging viral disease that can greatly reduce cassava productivity, while causing only mild aerial symptoms that develop late in infection. Early detection of CBSD enables better crop management and
Externí odkaz:
https://doaj.org/article/869e844ca6304118b7b40d796d372a15
Autor:
Amanda Ramcharan, Peter McCloskey, Kelsee Baranowski, Neema Mbilinyi, Latifa Mrisho, Mathias Ndalahwa, James Legg, David P. Hughes
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Convolutional neural network (CNN) models have the potential to improve plant disease phenotyping where the standard approach is visual diagnostics requiring specialized training. In scenarios where a CNN is deployed on mobile devices, models are pre
Externí odkaz:
https://doaj.org/article/9ba2aa48e8e94fa29686c74398e71114
Autor:
Matthew James Legg
Publikováno v:
Day 2 Tue, May 02, 2023.
Enhanced seismic velocity models (e.g. semblance or tomography) are key inputs for greenfield pore pressure prediction (PPP) in clastic basins, enabling velocity extraction along the planned well-path and also from a 3d earth-model surrounding the dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ff471afcd809a8faebb7d6edb2a6a8d
https://doi.org/10.4043/32393-ms
https://doi.org/10.4043/32393-ms
Autor:
Greg M. Thurber, Normann Goodwin, Lorraine Thompson, James Legg, Thomas Sandal, Adnan O. Abu-Yousif, Thomas A. Keating, Qifeng Qiu, Anna Kopp, Steven Vance, Eshita Khera, Ian Nessler
Targeted delivery of chemotherapeutics aims to increase efficacy and lower toxicity by concentrating drugs at the site-of-action, a method embodied by the seven current FDA-approved antibody–drug conjugates (ADC). However, a variety of pharmacokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bb7ab2805dd13cdbb4ee95f79492b5
https://doi.org/10.1158/0008-5472.c.6511984.v1
https://doi.org/10.1158/0008-5472.c.6511984.v1
Autor:
Luisa Chocarro, Leticia Fernandez-Rubio, María Jesús García-Granda, Ester Blanco, Ana Bocanegra, Miriam Echaide, Maider Garnica, Miren Zuazo, Colette Johnston, Carolyn J. Edwards, James Legg, Andrew J Pierce, Hugo Arasanz, Ruth Vera, Karina Ausin, Enrique Santamaría, Joaquín Fernández-Irigoyen, Grazyna Kochan, David Escors
A significant number of cancer patients do not benefit from PD-L1/PD-1 blockade immunotherapies. PD-1 and LAG-3 co-upregulation in T-cells is one of the major mechanisms of resistance by establishing a highly dysfunctional state in T-cells. To identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d848313fcb6f18fa869f1a6b34bf72b7
https://doi.org/10.1101/2023.03.10.23287087
https://doi.org/10.1101/2023.03.10.23287087
Autor:
Amanda Ramcharan, Kelsee Baranowski, Peter McCloskey, Babuali Ahmed, James Legg, David P. Hughes
Publikováno v:
Frontiers in Plant Science, Vol 8 (2017)
Cassava is the third largest source of carbohydrates for human food in the world but is vulnerable to virus diseases, which threaten to destabilize food security in sub-Saharan Africa. Novel methods of cassava disease detection are needed to support
Externí odkaz:
https://doaj.org/article/ee320817649b4db6b2ee16d65359f225
Autor:
Brice Kette Tocko-Marabena, Semballa Silla, Christophe Simiand, Innocent Zinga, James Legg, Bernard Reynaud, Helene Delatte
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182749 (2017)
After 2007, upsurges of whiteflies on cassava plants and high incidences of cassava diseases were observed in Central African Republic. This recent upsurge in the abundance of Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) was directly linked to
Externí odkaz:
https://doaj.org/article/57caddcbeecf46d7b00ac2ad47704403
Autor:
Thomas Sandal, Ian Nessler, Steven Vance, Thomas A. Keating, Anna Kopp, Lorraine Thompson, Eshita Khera, Adnan O. Abu-Yousif, Qifeng Qiu, Greg M. Thurber, Normann Goodwin, James Legg
Publikováno v:
Cancer Research. 80:1268-1278
Targeted delivery of chemotherapeutics aims to increase efficacy and lower toxicity by concentrating drugs at the site-of-action, a method embodied by the seven current FDA-approved antibody–drug conjugates (ADC). However, a variety of pharmacokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b8f338667a5db5f2954b8cbbd436a79
https://doi.org/10.1158/0008-5472.can-19-2295
https://doi.org/10.1158/0008-5472.can-19-2295