Zobrazeno 1 - 10
of 249
pro vyhledávání: '"James, Koropatnick"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
CD5 is a member of the scavenger receptor cysteine-rich superfamily that is expressed on T cells and a subset of B cells (B1a) cell and can regulate the T cell receptor signaling pathway. Blocking CD5 function may have therapeutic potential in treatm
Externí odkaz:
https://doaj.org/article/eca7bcaa1a1b457594ec3cc17d7d03c3
Autor:
Saman Maleki, Mikal El-Hajjar, Mithunah Krishnamoorthy, James Koropatnick, Lara Gerhardt, Rene Figueredo, Xiufen Zheng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/50fa51d34ff447fe94eea9eb86df5d91
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
CD5, a member of the scavenger receptor cysteine-rich superfamily, is a marker for T cells and a subset of B cells (B1a). CD5 associates with T-cell and B-cell receptors and increased CD5 is an indication of B cell activation. In tumor-infiltrating l
Externí odkaz:
https://doaj.org/article/8f476cabbabe4c56b682279a3256dc17
Autor:
Mikal El-Hajjar, Lara Gerhardt, Megan M Y Hong, Mithunah Krishnamoorthy, Rene Figueredo, Xiufen Zheng, James Koropatnick, Saman Maleki Vareki
Publikováno v:
Molecular Therapy. 31:535-551
Immune checkpoint blockade can induce potent and durable responses in patients with highly immunogenic mismatch repair-deficient tumors; however, these drugs are ineffective against immune-cold neuroblastoma tumors. To establish a role for a T cell-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6be47af0ce3e39a6867edc567c153a
https://doi.org/10.1016/j.ymthe.2022.08.025
https://doi.org/10.1016/j.ymthe.2022.08.025
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/93d7c089470e4442bbce70e1ba3ee2fa
Autor:
Karel Tyml, Scott Swarbreck, Cynthia Pape, Dan Secor, James Koropatnick, Qingping Feng, Ruud A. W. Veldhuizen, Sean E. Gill
Publikováno v:
Critical Care, Vol 21, Iss 1, Pp 1-12 (2017)
Abstract Background Despite many animal studies and clinical trials, mortality in sepsis remains high. This may be due to the fact that most experimental studies of sepsis employ young animals, whereas the majority of septic patients are elderly (60
Externí odkaz:
https://doaj.org/article/c5386ed2cde84f1ca490fd500ea6bffb
Autor:
Meng Zhang, Dian Gao, Yanmei Shi, Yifan Wang, Rakesh Joshi, Qiongfang Yu, Daheng Liu, Faizah Alotaibi, Yujuan Zhang, Hongmei Wang, Qing Li, Zhu-Xu Zhang, James Koropatnick, Weiping Min
Publikováno v:
Open Biology, Vol 9, Iss 10 (2019)
Blockade of inhibitory receptors (IRs) is one of the most effective immunotherapeutic approaches to treat cancer. Dysfunction of miRNAs is a major cause of aberrant expression of IRs and contributes to the immune escape of cancer cells. How miRNAs re
Externí odkaz:
https://doaj.org/article/4eee52878fc04db1ad59da3d3f931248
Autor:
Robert A. Uger, Jean C.Y. Wang, Liqing Jin, Nathan Mbong, Suzanne Trudel, James Koropatnick, Macarena Pampillo, Rene Figueredo, Saman Maleki Vareki, Eric L. Sievers, Emma Linderoth, Lisa D. Johnson, Stephane Viau, Tran Truong, Marilyse Charbonneau, Tapfuma Mutukura, Debbie Jin, Noel T. Vigo, Violetta House, Vivian Lee, Hui Chen, Vien Chai, Karen Dodge, Gloria H.Y. Lin, Xinli Pang, Mark Wong, Natasja Nielsen Viller, Penka S. Petrova
This figure shows our gating strategy and representative dot plots for our flow cytometry-based phagocytosis assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6502221f8e80340a26b595d5b018332
https://doi.org/10.1158/1078-0432.22466546
https://doi.org/10.1158/1078-0432.22466546
Autor:
Robert A. Uger, Jean C.Y. Wang, Liqing Jin, Nathan Mbong, Suzanne Trudel, James Koropatnick, Macarena Pampillo, Rene Figueredo, Saman Maleki Vareki, Eric L. Sievers, Emma Linderoth, Lisa D. Johnson, Stephane Viau, Tran Truong, Marilyse Charbonneau, Tapfuma Mutukura, Debbie Jin, Noel T. Vigo, Violetta House, Vivian Lee, Hui Chen, Vien Chai, Karen Dodge, Gloria H.Y. Lin, Xinli Pang, Mark Wong, Natasja Nielsen Viller, Penka S. Petrova
These four supplementary tables summarize the following: Supplementary Table 1. TTI-621 binding to human tumor cell lines Supplementary Table 2. TTI-621 binding to human primary tumor samples Supplementary Table 3. TTI-621 binding to peripheral blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f89a4b999cc379fed7b6c4fbda99d25
https://doi.org/10.1158/1078-0432.22466540
https://doi.org/10.1158/1078-0432.22466540
Autor:
Robert A. Uger, Jean C.Y. Wang, Liqing Jin, Nathan Mbong, Suzanne Trudel, James Koropatnick, Macarena Pampillo, Rene Figueredo, Saman Maleki Vareki, Eric L. Sievers, Emma Linderoth, Lisa D. Johnson, Stephane Viau, Tran Truong, Marilyse Charbonneau, Tapfuma Mutukura, Debbie Jin, Noel T. Vigo, Violetta House, Vivian Lee, Hui Chen, Vien Chai, Karen Dodge, Gloria H.Y. Lin, Xinli Pang, Mark Wong, Natasja Nielsen Viller, Penka S. Petrova
This figure shows representative hematology data from non-human primates (cynomolgus monkeys) dosed with TTI-621.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708e5703f5001ec46eb1a5af14761411
https://doi.org/10.1158/1078-0432.22466543.v1
https://doi.org/10.1158/1078-0432.22466543.v1