Zobrazeno 1 - 10
of 79
pro vyhledávání: '"James, Gee"'
Autor:
Phuong T. Vu, Chantal Chahine, Neil Chatterjee, Matthew T. MacLean, Sophia Swago, Abhi Bhattaru, Elizabeth W. Thompson, Anooshey Ikhlas, Edith Oteng, Lauren Davidson, Richard Tran, Mohamad Hazim, Pavan Raghupathy, Anurag Verma, Jeffrey Duda, James Gee, Valerie Luks, Victoria Gershuni, Gary Wu, Daniel Rader, Hersh Sagreiya, Walter R. Witschey, The Penn Medicine Biobank
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The study of muscle mass as an imaging-derived phenotype (IDP) may yield new insights into determining the normal and pathologic variations in muscle mass in the population. This can be done by determining 3D abdominal muscle mass from 12 di
Externí odkaz:
https://doaj.org/article/3f0c4ce531504627bd223662129fc0c7
Autor:
Sanaz Arezoumandan, Katheryn A.Q. Cousins, Daniel T. Ohm, MaKayla Lowe, Min Chen, James Gee, Jeffrey S. Phillips, Corey T. McMillan, Kelvin C. Luk, Andres Deik, Meredith A. Spindler, Thomas F. Tropea, Daniel Weintraub, David A. Wolk, Murray Grossman, Virginia Lee, Alice S. Chen‐Plotkin, Edward B. Lee, David J. Irwin
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 673-685 (2024)
Abstract Objective Alzheimer's disease neuropathologic change and alpha‐synucleinopathy commonly co‐exist and contribute to the clinical heterogeneity of dementia. Here, we examined tau epitopes marking various stages of tangle maturation to test
Externí odkaz:
https://doaj.org/article/cdc2ad75ef8743d99fac2e3feb9bcc6b
Autor:
Sylvia Mihailescu, Quinn Hlava, Philip A. Cook, Maria Luisa Mandelli, Suzee E. Lee, Bradley F. Boeve, Bradford C. Dickerson, Maria Luisa Gorno-Tempini, Emily Rogalski, Murray Grossman, James Gee, Corey T. McMillan, Christopher A. Olm
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionFrontotemporal lobar degeneration (FTLD) is associated with FTLD due to tau (FTLD-tau) or TDP (FTLD-TDP) inclusions found at autopsy. Arterial Spin Labeling (ASL) MRI is often acquired in the same session as a structural T1-weighted image
Externí odkaz:
https://doaj.org/article/df95660fbdbd499fb260b1ca808d1d37
Autor:
Ting Shen, Jacob W. Vogel, Jeffrey Duda, Jeffrey S. Phillips, Philip A. Cook, James Gee, Lauren Elman, Colin Quinn, Defne A. Amado, Michael Baer, Lauren Massimo, Murray Grossman, David J. Irwin, Corey T. McMillan
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-20 (2023)
Abstract Background TDP-43 proteinopathies represent a spectrum of neurological disorders, anchored clinically on either end by amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). The ALS–FTD spectrum exhibits a diverse range
Externí odkaz:
https://doaj.org/article/2b11c89bb7724f18adf67758d44d34c1
Autor:
Elizabeth Thompson, BSc, Jin-seo Kim, Abhijit Bhattaru, Phuong Vu, BSc, Sophia Swago, Elizabeth Donnelly, BSc, Xuemei zhang, BSc, Lipika Vuthuri, Kristen Lanzilotta, Annefleur Loth, Kevin Whitehead, MD, PhD, Jeffrey Duda, PhD, James Gee, Laura Almasy, Elizabeth Goldmuntz, Mark Fogel, Walter Witschey, PhD
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100136- (2024)
Externí odkaz:
https://doaj.org/article/5d8488f509a347fba427b09c3e833e85
Autor:
Daniel T. Ohm, Emma Rhodes, Alejandra Bahena, Noah Capp, MaKayla Lowe, Philip Sabatini, Winifred Trotman, Christopher A. Olm, Jeffrey Phillips, Karthik Prabhakaran, Katya Rascovsky, Lauren Massimo, Corey McMillan, James Gee, M. Dylan Tisdall, Paul A. Yushkevich, Edward B. Lee, Murray Grossman, David J. Irwin
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Frontotemporal dementia (FTD) is a spectrum of clinically and pathologically heterogenous neurodegenerative dementias. Clinical and anatomical variants of FTD have been described and associated with underlying frontotemporal lobar degeneration (FTLD)
Externí odkaz:
https://doaj.org/article/ccc895884b2a46adb76bedc4bbeb33e7
Autor:
Michael Hawrylycz, Maryann E Martone, Giorgio A Ascoli, Jan G Bjaalie, Hong-Wei Dong, Satrajit S Ghosh, Jesse Gillis, Ronna Hertzano, David R Haynor, Patrick R Hof, Yongsoo Kim, Ed Lein, Yufeng Liu, Jeremy A Miller, Partha P Mitra, Eran Mukamel, Lydia Ng, David Osumi-Sutherland, Hanchuan Peng, Patrick L Ray, Raymond Sanchez, Aviv Regev, Alex Ropelewski, Richard H Scheuermann, Shawn Zheng Kai Tan, Carol L Thompson, Timothy Tickle, Hagen Tilgner, Merina Varghese, Brock Wester, Owen White, Hongkui Zeng, Brian Aevermann, David Allemang, Seth Ament, Thomas L Athey, Cody Baker, Katherine S Baker, Pamela M Baker, Anita Bandrowski, Samik Banerjee, Prajal Bishwakarma, Ambrose Carr, Min Chen, Roni Choudhury, Jonah Cool, Heather Creasy, Florence D'Orazi, Kylee Degatano, Benjamin Dichter, Song-Lin Ding, Tim Dolbeare, Joseph R Ecker, Rongxin Fang, Jean-Christophe Fillion-Robin, Timothy P Fliss, James Gee, Tom Gillespie, Nathan Gouwens, Guo-Qiang Zhang, Yaroslav O Halchenko, Nomi L Harris, Brian R Herb, Houri Hintiryan, Gregory Hood, Sam Horvath, Bingxing Huo, Dorota Jarecka, Shengdian Jiang, Farzaneh Khajouei, Elizabeth A Kiernan, Huseyin Kir, Lauren Kruse, Changkyu Lee, Boudewijn Lelieveldt, Yang Li, Hanqing Liu, Lijuan Liu, Anup Markuhar, James Mathews, Kaylee L Mathews, Chris Mezias, Michael I Miller, Tyler Mollenkopf, Shoaib Mufti, Christopher J Mungall, Joshua Orvis, Maja A Puchades, Lei Qu, Joseph P Receveur, Bing Ren, Nathan Sjoquist, Brian Staats, Daniel Tward, Cindy T J van Velthoven, Quanxin Wang, Fangming Xie, Hua Xu, Zizhen Yao, Zhixi Yun, Yun Renee Zhang, W Jim Zheng, Brian Zingg
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002133 (2023)
Characterizing cellular diversity at different levels of biological organization and across data modalities is a prerequisite to understanding the function of cell types in the brain. Classification of neurons is also essential to manipulate cell typ
Externí odkaz:
https://doaj.org/article/5683e726eb424a3187544a44691a1d0f
Autor:
Manzar Ashtari, Philip Cook, Mikhail Lipin, Yinxi Yu, Gui-Shuang Ying, Albert Maguire, Jean Bennett, James Gee, Hui Zhang
Publikováno v:
Current Research in Neurobiology, Vol 4, Iss , Pp 100089- (2023)
The impact of changes in visual input on neuronal circuitry is complex and much of our knowledge on human brain plasticity of the visual systems comes from animal studies. Reinstating vision in a group of patients with low vision through retinal gene
Externí odkaz:
https://doaj.org/article/53fc31047aaf4981ab917f35a29449d2
Autor:
Katerina Placek, Michael Benatar, Joanne Wuu, Evadnie Rampersaud, Laura Hennessy, Vivianna M Van Deerlin, Murray Grossman, David J Irwin, Lauren Elman, Leo McCluskey, Colin Quinn, Volkan Granit, Jeffrey M Statland, Ted M Burns, John Ravits, Andrea Swenson, Jon Katz, Erik P Pioro, Carlayne Jackson, James Caress, Yuen So, Samuel Maiser, David Walk, Edward B Lee, John Q Trojanowski, Philip Cook, James Gee, Jin Sha, Adam C Naj, Rosa Rademakers, The CReATe Consortium, Wenan Chen, Gang Wu, J Paul Taylor, Corey T McMillan
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 1, Pp 1-18 (2020)
Abstract Amyotrophic lateral sclerosis (ALS) is a multi‐system disease characterized primarily by progressive muscle weakness. Cognitive dysfunction is commonly observed in patients; however, factors influencing risk for cognitive dysfunction remai
Externí odkaz:
https://doaj.org/article/c97ccf4df05c438e987a0ef12c4302e4
Autor:
M. Dylan Tisdall, Daniel T. Ohm, Rebecca Lobrovich, Sandhitsu R. Das, Gabor Mizsei, Karthik Prabhakaran, Ranjit Ittyerah, Sydney Lim, Corey T. McMillan, David A. Wolk, James Gee, John Q. Trojanowski, Edward B. Lee, John A. Detre, Paul Yushkevich, Murray Grossman, David J. Irwin
Publikováno v:
NeuroImage: Clinical, Vol 33, Iss , Pp 102913- (2022)
Frontotemporal lobar degeneration (FTLD) is a heterogeneous spectrum of age-associated neurodegenerative diseases that include two main pathologic categories of tau (FTLD-Tau) and TDP-43 (FTLD-TDP) proteinopathies. These distinct proteinopathies are
Externí odkaz:
https://doaj.org/article/bdcc86440dd24ea7bdac41da36329d85