Establishing Patient-Derived Xenograft (PDX) Models of Lymphomas.

Autor: Steel C; Department of Pathology, University of Cambridge, Cambridge, UK., James ER; Department of Pathology, University of Cambridge, Cambridge, UK., Matthews JD; Department of Pathology, University of Cambridge, Cambridge, UK., Turner SD; Department of Pathology, University of Cambridge, Cambridge, UK. sdt36@cam.ac.uk.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2865, pp. 429-448.

Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma.

Autor: Pucci P; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Lee LC; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK.; Merck & Co, 2000 Galloping Hill Rd, Kenilworth, NJ, 07033, USA., Han M; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK.; OncoSec, San Diego, CA, 92121, USA., Matthews JD; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Jahangiri L; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK.; Department of Life Sciences, Birmingham City University, Birmingham, UK.; Nottingham Trent University, School of Science & Technology, Clifton Lane, Nottingham, NG11 8NS, UK., Schlederer M; Department of Pathology, Division of Experimental and Translational Pathology, Medical University of Vienna, 1090, Vienna, Austria., Manners E; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK.; Chelsea and Westminster Hospital, NHS Foundation Trust, London, SW10 9NH, UK., Sorby-Adams A; MRC Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Hills Road, Cambridge, CB2 0QQ, UK., Kaggie J; Department of Radiology, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK., Trigg RM; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK.; Functional Genomics, GlaxoSmithKline, Stevenage, SG1 2NY, UK., Steel C; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Hare L; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK.; Department of Paediatric Haematology, Oncology and Palliative Care, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK., James ER; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Prokoph N; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Ducray SP; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK., Merkel O; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; European Research Initiative for ALK related malignancies (ERIA), Cambridge, CB2 0QQ, UK., Rifatbegovic F; St. Anna Children's Cancer Research Institute, CCRI, Zimmermannplatz 10, 1090, Vienna, Austria., Luo J; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20814, USA., Taschner-Mandl S; St. Anna Children's Cancer Research Institute, CCRI, Zimmermannplatz 10, 1090, Vienna, Austria., Kenner L; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; European Research Initiative for ALK related malignancies (ERIA), Cambridge, CB2 0QQ, UK.; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, Austria.; Center for Biomarker Research in Medicine (CBmed), Graz, Austria.; Christian Doppler Laboratory for Applied Metabolomics (CDL-AM), Medical University of Vienna, Vienna, Austria., Burke GAA; Department of Paediatric Haematology, Oncology and Palliative Care, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK., Turner SD; Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, CB20QQ, UK. sdt36@cam.ac.uk.; European Research Initiative for ALK related malignancies (ERIA), Cambridge, CB2 0QQ, UK. sdt36@cam.ac.uk.; Faculty of Medicine, Masaryk University, Brno, Czech Republic. sdt36@cam.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Apr 23; Vol. 15 (1), pp. 3422. Date of Electronic Publication: 2024 Apr 23.

Piloting delivery of PfSPZ vaccines for malaria through a cryogenic vaccine cold chain to travel and military medicine clinics.

Autor: James ER; Sanaria Inc, Rockville, MD 20850, USA., Church LWP; Sanaria Inc, Rockville, MD 20850, USA., Hoffman SL; Sanaria Inc, Rockville, MD 20850, USA., Richie TL; Sanaria Inc, Rockville, MD 20850, USA., Robertson BD; Walter Reed National Military Medical Center, Bethesda, MD 20889, USA., Hickey PW; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA., Schwartz DJ; Walter Reed National Military Medical Center, Bethesda, MD 20889, USA., Logan PT; Walter Reed National Military Medical Center, Bethesda, MD 20889, USA., Asare TD; Walter Reed National Military Medical Center, Bethesda, MD 20889, USA., Jones ML; Walter Reed National Military Medical Center, Bethesda, MD 20889, USA., Bay JL; Joint Base Lewis-McChord/Madigan Army Medical Center, Lewis-McChord, WA 98431, USA., Roschel AK; Joint Base Lewis-McChord/Madigan Army Medical Center, Lewis-McChord, WA 98431, USA., Pfeiffer JL; Joint Base Lewis-McChord/Madigan Army Medical Center, Lewis-McChord, WA 98431, USA., Acosta RW; Traveler's Medical Service, New York, NY 10022, USA., Schiavi E; Traveler's Medical Service, New York, NY 10022, USA., Acosta AM; Traveler's Medical Service, New York, NY 10022, USA., Noble M; Passport Health Silver Spring Travel Clinic, Silver Spring, MD 20903, USA., Henkel T; Passport Health Silver Spring Travel Clinic, Silver Spring, MD 20903, USA., Young C; Passport Health Silver Spring Travel Clinic, Silver Spring, MD 20903, USA.

Publikováno v: Journal of travel medicine [J Travel Med] 2024 Apr 06; Vol. 31 (3).

Safety and protective efficacy of PfSPZ Vaccine administered to HIV-negative and -positive Tanzanian adults.

Autor: Jongo S; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Church LWP; Sanaria Inc., Rockville, Maryland, USA., Milando F; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Qassim M; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Schindler T; Swiss Tropical Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Rashid M; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Tumbo A; Ifakara Health Institute (IHI), Bagamoyo, Tanzania.; Swiss Tropical Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Nyaulingo G; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Bakari BM; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Athuman Mbaga T; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Mohamed L; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Kassimu K; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Simon BS; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Mpina M; Ifakara Health Institute (IHI), Bagamoyo, Tanzania.; Swiss Tropical Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Zaidi I; Laboratory of Malaria Immunology and Vaccinology and., Duffy PE; Laboratory of Malaria Immunology and Vaccinology and., Swanson PA 2nd; Vaccine Research Center, NIH, Bethesda, Maryland, USA., Seder R; Vaccine Research Center, NIH, Bethesda, Maryland, USA., Herman JD; Division of Infectious Disease, Brigham and Women's Hospital, Boston, Massachusetts, USA.; The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA., Mendu M; The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA., Zur Y; The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA., Alter G; The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA., Kc N; Sanaria Inc., Rockville, Maryland, USA.; Protein Potential LLC, Rockville, Maryland, USA., Riyahi P; Sanaria Inc., Rockville, Maryland, USA., Abebe Y; Sanaria Inc., Rockville, Maryland, USA., Murshedkar T; Sanaria Inc., Rockville, Maryland, USA., James ER; Sanaria Inc., Rockville, Maryland, USA., Billingsley PF; Sanaria Inc., Rockville, Maryland, USA., Sim BKL; Sanaria Inc., Rockville, Maryland, USA.; Protein Potential LLC, Rockville, Maryland, USA., Richie TL; Sanaria Inc., Rockville, Maryland, USA., Daubenberger C; Swiss Tropical Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Abdulla S; Ifakara Health Institute (IHI), Bagamoyo, Tanzania., Hoffman SL; Sanaria Inc., Rockville, Maryland, USA.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Jan 09; Vol. 134 (6). Date of Electronic Publication: 2024 Jan 09.

Safety and Immunogenicity of Radiation-Attenuated PfSPZ Vaccine in Equatoguinean Infants, Children, and Adults.

Autor: Jongo SA; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., Urbano Nsue Ndong Nchama V; Ministry of Health and Social Welfare, Government of Equatorial Guinea, Malabo, Equatorial Guinea., Church LWP; Sanaria Inc., Rockville, Maryland., Olotu A; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., Manock SR; Sanaria Inc., Rockville, Maryland., Schindler T; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Mtoro A; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., Kc N; Sanaria Inc., Rockville, Maryland.; Protein Potential LLC, Rockville, Maryland., Devinsky O; New York University Langone Medical Center, New York, New York., Zan E; New York University Langone Medical Center, New York, New York., Hamad A; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., Nyakarungu E; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., Mpina M; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania.; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Deal A; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Bijeri JR; Ministry of Health and Social Welfare, Government of Equatorial Guinea, Malabo, Equatorial Guinea., Ondo Mangue ME; Ministry of Health and Social Welfare, Government of Equatorial Guinea, Malabo, Equatorial Guinea., Ntutumu Pasialo BE; Ministry of Health and Social Welfare, Government of Equatorial Guinea, Malabo, Equatorial Guinea., Nguema GN; Ministry of Health and Social Welfare, Government of Equatorial Guinea, Malabo, Equatorial Guinea., Rivas MR; Ministry of Health and Social Welfare, Government of Equatorial Guinea, Malabo, Equatorial Guinea., Chemba M; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., Ramadhani KK; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., James ER; Sanaria Inc., Rockville, Maryland., Stabler TC; Sanaria Inc., Rockville, Maryland., Abebe Y; Sanaria Inc., Rockville, Maryland., Riyahi P; Sanaria Inc., Rockville, Maryland., Saverino ES; Sanaria Inc., Rockville, Maryland., Sax J; Swiss Tropical and Public Health Institute, Allschwil, Switzerland., Hosch S; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Tumbo A; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania.; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Gondwe L; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., Segura JL; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Falla CC; MCD Global Health, Silver Spring, Maryland., Phiri WP; MCD Global Health, Silver Spring, Maryland., Hergott DEB; MCD Global Health, Silver Spring, Maryland., García GA; MCD Global Health, Silver Spring, Maryland., Maas C; Marathon EG Production, Ltd., Malabo Dos, Equatorial Guinea., Murshedkar T; Sanaria Inc., Rockville, Maryland., Billingsley PF; Sanaria Inc., Rockville, Maryland., Tanner M; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Ayekaba MO; Ministry of Health and Social Welfare, Government of Equatorial Guinea, Malabo, Equatorial Guinea., Sim BKL; Sanaria Inc., Rockville, Maryland.; Protein Potential LLC, Rockville, Maryland., Daubenberger C; Swiss Tropical and Public Health Institute, Allschwil, Switzerland.; University of Basel, Basel, Switzerland., Richie TL; Sanaria Inc., Rockville, Maryland., Abdulla S; Ifakara Health Institute, Bagamoyo Research and Training Centre, Bagamoyo, Tanzania., Hoffman SL; Sanaria Inc., Rockville, Maryland.

Publikováno v: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2023 May 09; Vol. 109 (1), pp. 138-146. Date of Electronic Publication: 2023 May 09 (Print Publication: 2023).