Výsledky vyhledávání - "James, Colin R"

Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer

Autor: Parkes, Eileen E., Savage, Kienan I., Lioe, Tong, Boyd, Clinton, Halliday, Sophia, Walker, Steven M., Lowry, Keith, Knight, Laura, Buckley, Niamh E., Grogan, Andrena, Logan, Gemma E., Clayton, Alison, Hurwitz, Jane, Kirk, Stephen J., Xu, Jiamei, Sidi, Fatima Abdullahi, Humphries, Matthew P., Bingham, Victoria, Ang, Melvyn, Askin, Conal, Bamford, Louise, Boyd, Ruth, Buckley, Miriam, Clarke, Jacqueline, Darragh, Lynn, Davis, Elaine, Foreman, Jennifer, Gallagher, Rebecca, Gill, Janine, Hanna, Michael, Hill, Naomi, Irwin, Gareth, Mallon, Peter, McAleer, Seamus, McAllister, Joanne, Morris, Melanie, Pierce, Nicole, Refsum, Sigi, Sloan, Samantha, Treanor, Sinead, James, Jacqueline, James, Colin R., Paul Harkin, D., Kennedy, Richard D., McIntosh, Stuart A.

Publikováno v: Parkes, E E, Savage, K I, Lioe, T, Boyd, C, Halliday, S, Walker, S M, Lowry, K, Knight, L, Buckley, N E, Grogan, A, Logan, G E, Clayton, A, Hurwitz, J, Kirk, S J, Xu, J, Sidi, F A, Humphries, M P, Bingham, V, Ang, M, Askin, C, Bamford, L, Boyd, R, Buckley, M, Clarke, J, Darragh, L, Davis, E, Foreman, J, Gallagher, R, Gill, J, Hanna, M, Hill, N, Irwin, G, Mallon, P, McAleer, S, McAllister, J, Morris, M, Pierce, N, Refsum, S, Sloan, S, Treanor, S, James, J, James, C R, Paul Harkin, D, Kennedy, R D & McIntosh, S A 2022, ' Activation of a cGAS-STING-mediated immune response predicts response to neoadjuvant chemotherapy in early breast cancer ', British Journal of Cancer, vol. 126, no. 2, pp. 247-258 . https://doi.org/10.1038/s41416-021-01599-0
British Journal of Cancer

Background The DNA-damage immune-response (DDIR) signature is an immune-driven gene expression signature retrospectively validated as predicting response to anthracycline-based therapy. This feasibility study prospectively evaluates the use of this a

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