Zobrazeno 1 - 10
of 815
pro vyhledávání: '"James, C Moon"'
Autor:
Noor Sharrack, Kristopher D. Knott, Gaurav S. Gulsin, Tushar Kotecha, Louise A. E. Brown, Jian L. Yeo, Aldostefano Porcari, Robert D. Adam, Sharmaine Thirunavukarasu, Amrit Chowdhary, Eylem Levelt, James C. Moon, Gerry P. McCann, Marianna Fontana, Peter Kellman, Theresa Munyombwe, Chris P. Gale, David L. Buckley, John P. Greenwood, Peter P. Swoboda, Sven Plein
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metformin is an antihyperglycemic used to treat type 2 diabetes mellitus (T2DM). Patients with T2DM are at increased risk of cardiovascular disease. We explored the association between metformin use and cardiovascular magnetic resonance (CMR
Externí odkaz:
https://doaj.org/article/f658e09e703244519798bd09cc870527
Autor:
Constantin-Cristian Topriceanu, Mit Shah, Matthew Webber, Fiona Chan, Hunain Shiwani, Marcus Richards, Jonathan Schott, Nishi Chaturvedi, James C. Moon, Alun D. Hughes, Aroon D. Hingorani, Declan P. O’Regan, Gabriella Captur
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Although APOE ε4 allele carriage confers a risk for coronary artery disease, its persistence in humans might be explained by certain survival advantages (antagonistic pleiotropy). Methods Combining data from ~ 37,000 persons from
Externí odkaz:
https://doaj.org/article/11cdd86813114bbcb62a5c1ef1c08698
Autor:
Magnus Lundin, Einar Heiberg, David Nordlund, Tom Gyllenhammar, Katarina Steding-Ehrenborg, Henrik Engblom, Marcus Carlsson, Dan Atar, Jesper van der Pals, David Erlinge, Rasmus Borgquist, Ardavan Khoshnood, Ulf Ekelund, Jannike Nickander, Raquel Themudo, Sabrina Nordin, Rebecca Kozor, Anish N. Bhuva, James C. Moon, Eva Maret, Kenneth Caidahl, Andreas Sigfridsson, Peder Sörensson, Erik B. Schelbert, Håkan Arheden, Martin Ugander
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Cardiovascular magnetic resonance (CMR) can accurately measure left ventricular (LV) mass, and several measures related to LV wall thickness exist. We hypothesized that prognosis can be used to select an optimal measure of wall thickness for
Externí odkaz:
https://doaj.org/article/731c84b925f342cbb059414a59be7d39
Autor:
Constantin-Cristian Topriceanu, Eesha Dev, Mahmood Ahmad, Rebecca Hughes, Hunain Shiwani, Matthew Webber, Kenan Direk, Andrew Wong, Martin Ugander, James C. Moon, Alun D. Hughes, Jane Maddock, Todd T. Schlegel, Gabriella Captur
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background DNA methylation (DNAm) age acceleration (AgeAccel) and cardiac age by 12-lead advanced electrocardiography (A-ECG) are promising biomarkers of biological and cardiac aging, respectively. We aimed to explore the relationships betwe
Externí odkaz:
https://doaj.org/article/e91430dc36f344b3b9b0d182e9b29e69
Autor:
Daniel M. Altmann, Catherine J. Reynolds, George Joy, Ashley D. Otter, Joseph M. Gibbons, Corinna Pade, Leo Swadling, Mala K. Maini, Tim Brooks, Amanda Semper, Áine McKnight, Mahdad Noursadeghi, Charlotte Manisty, Thomas A. Treibel, James C. Moon, COVIDsortium investigators, Rosemary J. Boyton
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Among the unknowns in decoding the pathogenesis of SARS-CoV-2 persistent symptoms in Long Covid is whether there is a contributory role of abnormal immunity during acute infection. It has been proposed that Long Covid is a consequence of eit
Externí odkaz:
https://doaj.org/article/a677c6017bb84e09bc50cdbc69054faa
Autor:
Sameer Zaman, Kavitha Vimalesvaran, Digby Chappell, Marta Varela, Nicholas S. Peters, Hunain Shiwani, Kristopher D. Knott, Rhodri H. Davies, James C. Moon, Anil A. Bharath, Nick WF Linton, Darrel P. Francis, Graham D. Cole, James P. Howard
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss 1, Pp 101040- (2024)
Background: Late gadolinium enhancement (LGE) of the myocardium has significant diagnostic and prognostic implications, with even small areas of enhancement being important. Distinguishing between definitely normal and definitely abnormal LGE images
Externí odkaz:
https://doaj.org/article/8ad249f6ef7f44a8b9f40612520a252f
Autor:
Ashwin Roy, Ravi Vijapurapu, Hibba Kurdi, Christopher Orsborne, Peter Woolfson, Manish Kalla, Ana Jovanovic, Christopher A. Miller, James C. Moon, Derralynn A. Hughes, Tarekegn Geberhiwot, Richard P. Steeds
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Fabry disease (FD) is an X-linked deficiency of alpha-galactosidase-A, leading to lysosomal storage of sphingolipids in multiple organs. Myocardial accumulation contributes to arrhythmia and sudden death, the most common cause of FD mortality. Theref
Externí odkaz:
https://doaj.org/article/13d803830aff4ff8874eea70c7935997
Autor:
Jannike Nickander, Ben Cole, Sabrina Nordin, Ravi Vijapurapu, Richard P. Steeds, James C. Moon, Peter Kellman, Martin Ugander, Rebecca Kozor
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Fabry disease (FD) is a rare lysosomal storage disorder resulting in myocardial sphingolipid accumulation which is detectable by cardiovascular magnetic resonance as low native T1. However, myocardial T1 contains signal from intramyocardial
Externí odkaz:
https://doaj.org/article/6923def0a5324d6abc8181245e6c9529
Autor:
Constantin-Cristian Topriceanu, Massimiliano Fornasiero, Han Seo, Matthew Webber, Kathryn E. Keenan, Karl F. Stupic, Rüdiger Bruehl, Bernd Ittermann, Kirsty Price, Louise McGrath, Wenjie Pang, Alun D. Hughes, Reza Nezafat, Peter Kellman, Iain Pierce, James C. Moon, Gabriella Captur
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Introduction A long T2 relaxation time can reflect oedema, and myocardial inflammation when combined with increased plasma troponin levels. Cardiovascular magnetic resonance (CMR) T2 mapping therefore has potential to provide a key diagnosti
Externí odkaz:
https://doaj.org/article/caef70cde30d4ae6831d1421826c142d
Autor:
Mashael Alfarih, João B. Augusto, Kristopher D. Knott, Nasri Fatih, M. Praveen Kumar, Redha Boubertakh, Alun D. Hughes, James C. Moon, Sebastian Weingärtner, Gabriella Captur
Publikováno v:
BMC Medical Imaging, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background To assess the feasibility of biventricular SAPPHIRE T1 mapping in vivo across field strengths using diastolic, systolic and dark-blood (DB) approaches. Methods 10 healthy volunteers underwent same-day non-contrast cardiovascular m
Externí odkaz:
https://doaj.org/article/c8d421e9a9e14b85ad3aa811c8002fa3