Zobrazeno 1 - 10
of 508
pro vyhledávání: '"James, B Rowe"'
Autor:
Evgeniia Lobanova, Yu P. Zhang, Derya Emin, Jack Brelstaff, Lakmini Kahanawita, Maura Malpetti, Annelies Quaegebeur, Kathy Triantafilou, Martha Triantafilou, Henrik Zetterberg, James B. Rowe, Caroline H. Williams-Gray, Clare Elizabeth Bryant, David Klenerman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Immunotherapeutic strategies for Alzheimer’s and Parkinson’s disease would be facilitated by better measures of inflammation. Here we established an ultra-sensitive single-molecule pull-down immunoassay combined with direct stochastic op
Externí odkaz:
https://doaj.org/article/3b89562d5e954dab9038f1d373df047b
Autor:
Alberto Benussi, Enrico Premi, Mario Grassi, Antonella Alberici, Valentina Cantoni, Stefano Gazzina, Silvana Archetti, Roberto Gasparotti, Giorgio G. Fumagalli, Arabella Bouzigues, Lucy L. Russell, Kiran Samra, David M. Cash, Martina Bocchetta, Emily G. Todd, Rhian S. Convery, Imogen Swift, Aitana Sogorb-Esteve, Carolin Heller, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Raquel Sanchez-Valle, Fermin Moreno, Robert Jr. Laforce, Caroline Graff, Matthis Synofzik, Daniela Galimberti, James B. Rowe, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, Rik Vandenberghe, Alexandre Mendonça, Pietro Tiraboschi, Chris R. Butler, Isabel Santana, Alexander Gerhard, Isabelle Le Ber, Florence Pasquier, Simon Ducharme, Johannes Levin, Sandro Sorbi, Markus Otto, Alessandro Padovani, Jonathan D. Rohrer, Barbara Borroni, Genetic Frontotemporal dementia Initiative (GENFI)
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background The Genetic Frontotemporal Initiative Staging Group has proposed clinical criteria for the diagnosis of prodromal frontotemporal dementia (FTD), termed mild cognitive and/or behavioral and/or motor impairment (MCBMI). The objectiv
Externí odkaz:
https://doaj.org/article/13a74e32930c440d9a0c8f0b5b590de2
Autor:
David J. Whiteside, Negin Holland, Kamen A. Tsvetanov, Elijah Mak, Maura Malpetti, George Savulich, P. Simon Jones, Michelle Naessens, Matthew A. Rouse, Tim D. Fryer, Young T. Hong, Franklin I. Aigbirhio, Eoin Mulroy, Kailash P. Bhatia, Timothy Rittman, John T. O’Brien, James B. Rowe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract There is extensive synaptic loss from frontotemporal lobar degeneration, in preclinical models and human in vivo and post mortem studies. Understanding the consequences of synaptic loss for network function is important to support translatio
Externí odkaz:
https://doaj.org/article/ab6733cf5df64638bd28121108e81c94
Autor:
Siddharth Ramanan, Ajay D. Halai, Lorna Garcia-Penton, Alistair G. Perry, Nikil Patel, Katie A. Peterson, Ruth U. Ingram, Ian Storey, Stefano F. Cappa, Eleonora Catricala, Karalyn Patterson, James B. Rowe, Peter Garrard, Matthew A. Lambon Ralph
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2023)
Abstract Background Clinical variants of primary progressive aphasia (PPA) are diagnosed based on characteristic patterns of language deficits, supported by corresponding neural changes on brain imaging. However, there is (i) considerable phenotypic
Externí odkaz:
https://doaj.org/article/ba662adda8e8404cb774cc5b9b49df3e
Autor:
Kiran Samra, Georgia Peakman, Amy M. MacDougall, Arabella Bouzigues, Caroline V. Greaves, Rhian S. Convery, John C. vanSwieten, Lize Jiskoot, Harro Seelaar, Fermin Moreno, Raquel Sanchez‐Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre deMendonça, Chris R. Butler, Alexander Gerhard, Simon Ducharme, Isabelle Le Ber, Pietro Tiraboschi, Isabel Santana, Florence Pasquier, Johannes Levin, Markus Otto, Sandro Sorbi, Jonathan D. Rohrer, Lucy L. Russell, Genetic FTD Initiative (GENFI)
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION We aimed to expand the range of the frontotemporal dementia (FTD) phenotypes assessed by the Clinical Dementia Rating Dementia Staging Instrument plus National Alzheimer's Coordinating Center Behavior and Language Domains (CDR p
Externí odkaz:
https://doaj.org/article/8ed7a9e8c76e4d6ca6c25a487b06eec3
Autor:
Tanrada Pansuwan, Annelies Quaegebeur, Sanne S. Kaalund, Eric Hidari, Mayen Briggs, James B. Rowe, Timothy Rittman
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract The development of novel treatments for Progressive Supranuclear Palsy (PSP) is hindered by a knowledge gap of the impact of neurodegenerative neuropathology on brain structure and function. The current standard practice for measuring postmo
Externí odkaz:
https://doaj.org/article/874c239c0f8d4bf0ab70c2dbddfe21fa
Autor:
Abbe Ullgren, Linn Öijerstedt, Jennie Olofsson, Sofia Bergström, Julia Remnestål, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Barbara Borroni, Raquel Sanchez-Valle, Fermin Moreno, Robert Laforce, Matthis Synofzik, Daniela Galimberti, James B. Rowe, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, Rik Vandenberghe, Alexandre de Mendonça, Pietro Tirabosch, Isabel Santana, Simon Ducharme, Chris R. Butler, Alexander Gerhard, Markus Otto, Arabella Bouzigues, Lucy Russell, Imogen J. Swift, Aitana Sogorb-Esteve, Carolin Heller, Jonathan D. Rohrer, Anna Månberg, Peter Nilsson, Caroline Graff, on behalf of the Genetic Frontotemporal Dementia Initiative (GENFI)
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background Plasma biomarkers reflecting the pathology of frontotemporal dementia would add significant value to clinical practice, to the design and implementation of treatment trials as well as our understanding of disease mechanisms. The a
Externí odkaz:
https://doaj.org/article/07eda451536c4719977177dd2e2955fe
Autor:
Tiago Azevedo, Richard A. I. Bethlehem, David J. Whiteside, Nol Swaddiwudhipong, James B. Rowe, Pietro Lió, Timothy Rittman, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-15 (2023)
Abstract Background Identifying prediagnostic neurodegenerative disease is a critical issue in neurodegenerative disease research, and Alzheimer’s disease (AD) in particular, to identify populations suitable for preventive and early disease-modifyi
Externí odkaz:
https://doaj.org/article/ea7d269a1d1c438e81eea5acb5fed365
Autor:
Rebecca S. Williams, Natalie E. Adams, Laura E. Hughes, Matthew A. Rouse, Alexander G. Murley, Michelle Naessens, Duncan Street, Negin Holland, James B. Rowe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Self-report scales are widely used in cognitive neuroscience and psychology. However, they rest on the central assumption that respondents engage meaningfully. We hypothesise that this assumption does not hold for many patients, especially t
Externí odkaz:
https://doaj.org/article/cb2dd1242c3f43fcb9bed820594f2ca8
Autor:
Alistair Perry, Laura E. Hughes, Natalie E. Adams, Michelle Naessens, Niels A. Kloosterman, Matthew A. Rouse, Alexander G. Murley, Duncan Street, P. Simon Jones, James B. Rowe
Publikováno v:
NeuroImage: Clinical, Vol 44, Iss , Pp 103671- (2024)
The consequences of frontotemporal lobar degeneration include changes in prefrontal cortical neurophysiology, with abnormalities of neural dynamics reported in the beta frequency range (14–30 Hz) that correlate with functional severity. We examined
Externí odkaz:
https://doaj.org/article/fb0bc11b9ec4436c85e0049fd7bb33ad