Natural prevalence of hepatitis C virus (HCV) variants resistant to protease and polymerase inhibitors in patients infected with HCV genotype 1 in Tunisia

Autor: Jennnifer Papuchon, Jameleddine Aissa Larousse, Hervé Fleury, Mohamed Mssadak Azzouz, Pascale Trimoulet, Nabyl Ben Mami, Patricia Recordon-Pinson, Henda Triki, Imed Cheikh

Publikováno v: Journal of Medical Virology. 86:1350-1359

Hepatitis C virus (HCV) protease inhibitors (PIs) and polymerase inhibitors: nucleos(t)ide inhibitors (NS5B-NIs) and non-nucleos(t)ide inhibitors (NS5B-NNIs) have been recently developed to inhibit protease (NS3) or polymerase (NS5B) activities. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72b1370f84eeb416f49b1623ed3b18a3
https://doi.org/10.1002/jmv.23958

Prevalence of hepatitis C virus (HCV) variants resistant to NS5A inhibitors in naïve patients infected with HCV genotype 1 in Tunisia

Autor: Jameleddine Aissa Larousse, Pascale Trimoulet, Nabyl Ben Mami, Brigitte Tauzin, Patricia Pinson, Hervé Fleury, Imed Cheikh, Henda Triki, Mohamed Mssadak Azzouz

Publikováno v: Virology Journal
Virology Journal, BioMed Central, 2015, 12, ⟨10.1186/s12985-015-0318-0⟩
Virology Journal, 2015, 12, ⟨10.1186/s12985-015-0318-0⟩

International audience; Background: Hepatitis C virus (HCV) non-structural protein 5A (NS5A) inhibitors have been recently developed to inhibit NS5A activities and have been approved for the treatment of HCV infection. However the drawback of these d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2590fe39044baf41a8e2d9b167978522