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Integrated in vivo functional screens and multi-omics analyses identify α-2,3-sialylation as essential for melanoma maintenance.

Autor: Agrawal P; Department of Pathology, NYU Grossman School of Medicine, New York.; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, NYU Langone Health.; Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York., Chen S; Department of Chemistry, New York University., de Pablos A; Department of Pathology, NYU Grossman School of Medicine, New York.; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, NYU Langone Health.; Centro Nacional de Investigaciones Oncologicas (CNIO), Madrid, Spain., Jame-Chenarboo F; Department of Chemistry, University of Alberta, Edmonton, Canada., Miera Saenz de Vega E; Department of Dermatology, NYU Grossman School of Medicine, New York., Darvishian F; Department of Pathology, NYU Grossman School of Medicine, New York., Osman I; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, NYU Langone Health.; Department of Dermatology, NYU Grossman School of Medicine, New York., Lujambio A; Icahn School of Medicine at Mount Sinai, New York., Mahal LK; Department of Chemistry, New York University.; Department of Chemistry, University of Alberta, Edmonton, Canada., Hernando E; Department of Pathology, NYU Grossman School of Medicine, New York.; Interdisciplinary Melanoma Cooperative Group, Perlmutter Cancer Center, NYU Langone Health.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 12. Date of Electronic Publication: 2024 Mar 12.