Intracellular delivery of peptides via association with ubiquitin or SUMO-1 coupled to protein transduction domains

Autor: Jalinot Pierre, Vitte Anne-Laure

Publikováno v: BMC Biotechnology, Vol 8, Iss 1, p 24 (2008)

Abstract Background We previously developed small hybrid proteins consisting of SUMO-1 linked to an heptapeptide fused to the Tat protein transduction domain (PTD). The heptapeptide motif was selected from a library of random sequences to specificall

Externí odkaz: https://doaj.org/article/e5fa6fbb7e7f4bdcad34dc453741eed6

Human TAF II 28 Interacts with the Human T Cell Leukemia Virus Type I Tax Transactivator and Promotes its Transcriptional Activity

Autor: Caron, Cecile, Mengus, Gabrielle, Dubrowskaya, Veronica, Roisin, Armelle, Davidson, Irwin, Jalinot, Pierre

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1997 Apr . 94(8), 3662-3667.

Externí odkaz: https://www.jstor.org/stable/41886

A Novel Screen for Expression Regulators of the Telomeric Protein TRF2 Identified Small Molecules That Impair TRF2 Dependent Immunosuppression and Tumor Growth

Autor: El Maï, Mounir, Janho Dit Hreich, Serena, Gaggioli, Cedric, Roisin, Armelle, Wagner, Nicole, Ye, Jing, Jalinot, Pierre, Cherfils-Vicini, Julien, Gilson, Eric

Publikováno v: Cancers
Cancers, MDPI, 2021, 13 (12), pp.2998. ⟨10.3390/cancers13122998⟩
Cancers, 2021, 13 (12), pp.2998. ⟨10.3390/cancers13122998⟩
Cancers, Vol 13, Iss 2998, p 2998 (2021)
Volume 13
Issue 12

Simple Summary The telomeric protein TRF2 (Telomeric repeat-binding factor 2) is upregulated in human cancers and associated with poor prognosis. TRF2 oncogenic properties rely on its intrinsic telomere protective role, but also on cell extrinsic eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::aa12607eb7e9f5e8c9e26cc7ba00a25c
https://hal.archives-ouvertes.fr/hal-03452217

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1

Autor: Jalinot, Pierre

Publikováno v: Oncotarget
Oncotarget, 2021

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::01ff42b73048a9148c4649384a33c9c1
https://hal.archives-ouvertes.fr/hal-03452187

HTLV-1 Tax plugs and freezes UPF1 helicase leading to nonsense-mediated mRNA decay inhibition

Autor: Fiorini, Francesca, Robin, Jean-Philippe, Kanaan, Joanne, Borowiak, Malgorzata, Croquette, Vincent, Le Hir, Hervé, Jalinot, Pierre, Mocquet, Vincent

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-017-02793-6⟩
Nature Communications, Nature Publishing Group, 2018, 9 (1), ⟨10.1038/s41467-017-02793-6⟩

Up-Frameshift Suppressor 1 Homolog (UPF1) is a key factor for nonsense-mediated mRNA decay (NMD), a cellular process that can actively degrade mRNAs. Here, we study NMD inhibition during infection by human T-cell lymphotropic virus type I (HTLV-1) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9cd1ff672f55ddf51c8c53edc762c2ec
http://link.springer.com/article/10.1038/s41467-017-02793-6