Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jaleal Sanjak"'
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Glioblastoma (GBM) is the most aggressive and common malignant primary brain tumor; however, treatment remains a significant challenge. This study aims to identify drug repurposing or repositioning candidates for GBM by developing
Externí odkaz:
https://doaj.org/article/65a6c029659843d1b671a712575126f8
Autor:
William Z. Kariampuzha, Gioconda Alyea, Sue Qu, Jaleal Sanjak, Ewy Mathé, Eric Sid, Haley Chatelaine, Arjun Yadaw, Yanji Xu, Qian Zhu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background The United Nations recently made a call to address the challenges of an estimated 300 million persons worldwide living with a rare disease through the collection, analysis, and dissemination of disaggregated data. Epidemiologic In
Externí odkaz:
https://doaj.org/article/97c68f5ddac148e2af07b15e158462a3
Autor:
Haley A. S. Chatelaine, Yulu Chen, John Braisted, Su H. Chu, Qingwen Chen, Meryl Stav, Sofina Begum, Joann Diray-Arce, Jaleal Sanjak, Mengna Huang, Jessica Lasky-Su, Ewy A. Mathé
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 346 (2023)
Understanding the molecular underpinnings of disease severity and progression in human studies is necessary to develop metabolism-related preventative strategies for severe COVID-19. Metabolites and metabolic pathways that predispose individuals to s
Externí odkaz:
https://doaj.org/article/3b7c75ccfea1445b85b4f34c3339cc12
Autor:
Molykutty J. Aryankalayil, Shannon Martello, Michelle A. Bylicky, Sunita Chopra, Jared M. May, Aman Shankardass, Laurel MacMillan, Landy Sun, Jaleal Sanjak, Claire Vanpouille-Box, Iris Eke, C. Norman Coleman
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background Radiation therapy is integral to effective thoracic cancer treatments, but its application is limited by sensitivity of critical organs such as the heart. The impacts of acute radiation-induced damage and its chronic effects on no
Externí odkaz:
https://doaj.org/article/63b6648b6e304baaad201a8aeb009217
Autor:
Sunita Chopra, Maria Moroni, Jaleal Sanjak, Laurel MacMillan, Bernadette Hritzo, Shannon Martello, Michelle Bylicky, Jared May, C. Norman Coleman, Molykutty J. Aryankalayil
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Gottingen minipigs mirror the physiological radiation response observed in humans and hence make an ideal candidate model for studying radiation biodosimetry for both limited-sized and mass casualty incidents. We examined the whole blood gen
Externí odkaz:
https://doaj.org/article/a2516ae3c6894857babcede544e3384f
Autor:
William Z. Kariampuzha, Gioconda Alyea, Sue Qu, Jaleal Sanjak, Ewy Mathé, Eric Sid, Haley Chatelaine, Arjun Yadaw, Yanji Xu, Qian Zhu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/d37d48a7b5a74170b5701070fb5040d3
Background Glioblastoma (GBM) is the most aggressive and common malignant primary brain tumor; however, treatment remains a significant challenge. This study aims to identify drug repurposing candidates for GBM by developing an integrative rare disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b69a36554fae804c2efb40517859428
https://doi.org/10.21203/rs.3.rs-2809689/v1
https://doi.org/10.21203/rs.3.rs-2809689/v1
Publikováno v:
bioRxiv
Structured AbstractObjectiveIdentifying sets of rare diseases with shared aspects of etiology and pathophysiology may enable drug repurposing and/or platform based therapeutic development. Toward that aim, we utilized an integrative knowledge graph-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446bd94efe63247a0745a26707f98ec0
https://doi.org/10.1101/2023.02.15.528673
https://doi.org/10.1101/2023.02.15.528673
Autor:
Michelle A. Bylicky, Molykutty J. Aryankalayil, Landy Sun, Claire Vanpouille-Box, Jared M. May, C. Norman Coleman, Iris Eke, Sunita Chopra, Jaleal Sanjak, Aman Shankardass, Laurel MacMillan, Shannon Martello
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-18 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background Radiation therapy is integral to effective thoracic cancer treatments, but its application is limited by sensitivity of critical organs such as the heart. The impacts of acute radiation-induced damage and its chronic effects on normal hear
Autor:
Bernadette Hritzo, Laurel MacMillan, Molykutty J. Aryankalayil, Jaleal Sanjak, Sunita Chopra, Shannon Martello, Maria Moroni, Jared M. May, C. Norman Coleman, Michelle A. Bylicky
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Gottingen minipigs mirror the physiological radiation response observed in humans and hence make an ideal candidate model for studying radiation biodosimetry for both limited-sized and mass casualty incidents. We examined the whole blood gene express