Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jakub Zahumenský"'
Autor:
Shamoon Naseem, Jakub Zahumenský, Carla E. Lanze, Lois M. Douglas, Jan Malínský, James B. Konopka
Publikováno v:
mSphere, Vol 9, Iss 12 (2024)
ABSTRACT The plasma membrane is critical for the virulence of the human fungal pathogen Candida albicans. In addition to functioning as a protective barrier, the plasma membrane plays dynamic roles in a wide range of functions needed for virulence in
Externí odkaz:
https://doaj.org/article/c34ccab149d844f982cdac1a2acaf5c8
Autor:
Jakub Zahumenský, Caroline Mota Fernandes, Petra Veselá, Maurizio Del Poeta, James B. Konopka, Jan Malínský
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Sphingolipids are essential building blocks of eukaryotic membranes and important signaling molecules that are regulated tightly in response to environmental and physiological inputs. While their biosynthetic pathway has been well-described,
Externí odkaz:
https://doaj.org/article/aeacbcde1ecf440c98ec1449610fafdd
Autor:
Paulína Káňovičová, Petra Čermáková, Dominika Kubalová, Lenka Bábelová, Petra Veselá, Martin Valachovič, Jakub Zahumenský, Anton Horváth, Jan Malínský, Mária Balážová
Publikováno v:
The Journal of Biological Chemistry
Barth syndrome (BTHS) is an inherited mitochondrial disorder characterized by a decrease in total cardiolipin and the accumulation of its precursor monolysocardiolipin due to the loss of the transacylase enzyme tafazzin. However, the molecular basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde4a52087aa3b610bb0be1c6a81a9d6
https://doi.org/10.1016/j.jbc.2021.101462
https://doi.org/10.1016/j.jbc.2021.101462
Publikováno v:
FEMS Yeast Research. 17
Multidrug transporters are often responsible for failure of medical treatment, since they expel a variety of structurally and functionally unrelated drugs out of the cell. We found that the fluorescent probe diS-C3(3) is a substrate of not only Pdr5p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8dcd33fcad683097fe643f980880ac
https://doi.org/10.1093/femsyr/fox073
https://doi.org/10.1093/femsyr/fox073
Autor:
Karel Sigler, Andrea Svenkrtova, Otakar Hlaváček, Dana Gášková, Tomáš Hendrych, Iva Jančíková, Jakub Zahumenský, Jaromír Plášek, Andrea Drietomská
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1859(10)
Tok1p is a highly specific yeast plasma membrane potassium channel with strong outward directionality. Its opening is induced by membrane depolarization. Although the biophysical properties of Tok1p are well-described, its potentially important physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba1af3649fff15eb017e3a209d5ff79
https://pubmed.ncbi.nlm.nih.gov/28669766
https://pubmed.ncbi.nlm.nih.gov/28669766
Publikováno v:
Journal of bioenergetics and biomembranes. 49(3)
Yeast cells exhibit a negative surface potential due to negative charges at the cell membrane surface. Consequently, local concentrations of cations at the periplasmic membrane surface may be significantly increased compared to their bulk environment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e21cd77f804cec59b242c2e8dca46ba
https://pubmed.ncbi.nlm.nih.gov/28405872
https://pubmed.ncbi.nlm.nih.gov/28405872
Autor:
Dana Gášková, Jakub Zahumenský, Ivana Benešová, Jaromír Plášek, Ľuboslava Buriánková, Karel Sigler
Publikováno v:
FEMS Yeast Research. 13:782-795
The effect of alcohols on cell membrane proteins has originally been assumed to be mediated by their primary action on membrane lipid matrix. Many studies carried out later on both animal and yeast cells have revealed that ethanol and other alcohols
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84290798953ede09c5685ef44d1ffe36
https://doi.org/10.1111/1567-1364.12088
https://doi.org/10.1111/1567-1364.12088
Autor:
Jaroslav Zamastil, Jakub Benda
This book highlights the power and elegance of algebraic methods of solving problems in quantum mechanics. It shows that symmetries not only provide elegant solutions to problems that can be solved exactly, but also substantially simplify problems th
