Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jakub W, Wojciechowski"'
Autor:
Vincent Guerlais, Nina Allouch, E. Ashley Moseman, Alicja W. Wojciechowska, Jakub W. Wojciechowski, Isabel Marcelino
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The free-living amoeba Naegleria fowleri (NF) causes a rare but lethal parasitic meningoencephalitis (PAM) in humans. Currently, this disease lacks effective treatments and the specific molecular mechanisms that govern NF pathogenesis and host brain
Externí odkaz:
https://doaj.org/article/f37d226e6a254d8aaba65b5dd28ebc4f
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Amyloid proteins are often associated with the onset of diseases, including Alzheimer’s, Parkinson’s and many others. However, there is a wide class of functional amyloids that are involved in physiological functions, e.g., formation of
Externí odkaz:
https://doaj.org/article/433a3af5e4df498a96eb92524541fa2b
Autor:
Jakub W Wojciechowski, Emirhan Tekoglu, Marlena Gąsior-Głogowska, Virginie Coustou, Natalia Szulc, Monika Szefczyk, Marta Kopaczyńska, Sven J Saupe, Witold Dyrka
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 12, p e1010787 (2022)
NLR proteins are intracellular receptors constituting a conserved component of the innate immune system of cellular organisms. In fungi, NLRs are characterized by high diversity of architectures and presence of amyloid signaling. Here, we explore the
Externí odkaz:
https://doaj.org/article/20da7749729543e6904b2828fb499ec3
Autor:
Muntasir Kamal, Levon Tokmakjian, Jessica Knox, Peter Mastrangelo, Jingxiu Ji, Hao Cai, Jakub W Wojciechowski, Michael P Hughes, Kristóf Takács, Xiaoquan Chu, Jianfeng Pei, Vince Grolmusz, Malgorzata Kotulska, Julie Deborah Forman-Kay, Peter J Roy
Publikováno v:
eLife, Vol 11 (2022)
How the cuticles of the roughly 4.5 million species of ecdysozoan animals are constructed is not well understood. Here, we systematically mine gene expression datasets to uncover the spatiotemporal blueprint for how the chitin-based pharyngeal cuticl
Externí odkaz:
https://doaj.org/article/7f96998fa7ed4879838769df2846b158
Autor:
Natalia Szulc, Michał Burdukiewicz, Marlena Gąsior-Głogowska, Jakub W. Wojciechowski, Jarosław Chilimoniuk, Paweł Mackiewicz, Tomas Šneideris, Vytautas Smirnovas, Malgorzata Kotulska
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Several disorders are related to amyloid aggregation of proteins, for example Alzheimer’s or Parkinson’s diseases. Amyloid proteins form fibrils of aggregated beta structures. This is preceded by formation of oligomers—the most cytotox
Externí odkaz:
https://doaj.org/article/1b581be9c50f488f8323d496d600981b
Autor:
Michał Burdukiewicz, Dominik Rafacz, Agnieszka Barbach, Katarzyna Hubicka, Laura Bąkała, Anna Lassota, Jakub Stecko, Natalia Szymańska, Jakub W Wojciechowski, Dominika Kozakiewicz, Natalia Szulc, Jarosław Chilimoniuk, Izabela Jęśkowiak, Marlena Gąsior-Głogowska, Małgorzata Kotulska
Publikováno v:
Nucleic Acids Research. 51:D352-D357
Information about the impact of interactions between amyloid proteins on their fibrillization propensity is scattered among many experimental articles and presented in unstructured form. We manually curated information located in almost 200 publicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d77f51b38d98f298403972f61ccdec
https://doi.org/10.1093/nar/gkac882
https://doi.org/10.1093/nar/gkac882
Autor:
Jessica Knox, Levon Tokmakjian, Muntasir Kamal, Peter Mastrangelo, Jingxiu Ji, Hao Cai, Jakub W Wojciechowski, Michael P Hughes, Kristóf Takács, Xiaoquan Chu, Jianfeng Pei, Vince Grolmusz, Malgorzata Kotulska, Julie Deborah Forman-Kay, Peter J Roy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::358d54dcd07886c7d50af8d760495db3
https://doi.org/10.7554/elife.79396.sa2
https://doi.org/10.7554/elife.79396.sa2
Publikováno v:
Molecules, Vol 24, Iss 18, p 3365 (2019)
To successfully design and optimize the application of hydrogel matrices one has to effectively combine computational design tools with experimental methods. In this context, one of the most promising techniques is molecular modeling, which requires
Externí odkaz:
https://doaj.org/article/fdbc4dd11c8b402882448f39c53a02b3
Amyloids are protein aggregates usually associated with their contribution to several diseases e.g., Alzheimer's and Parkinson's. However, they are also beneficially utilized by many organisms in physiological roles, such as microbial biofilm formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fda43a1c2e371c7ddbef488e993ac578
https://doi.org/10.1101/2022.07.07.499150
https://doi.org/10.1101/2022.07.07.499150
Autor:
Jakub W. Wojciechowski, Emirhan Tekoglu, Marlena Gąsior-Głogowska, Virginie Coustou, Natalia Szulc, Monika Szefczyk, Marta Kopaczyńska, Sven J. Saupe, Witold Dyrka
NLR proteins are intracellular receptors constituting a conserved component of the innate immune system of multicellular organisms. In fungi, NLRs are characterized by high diversity of architectures and presence of amyloid signaling. Here, we explor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4bb01dbfd4bde1c7013f7735e7ee78
https://doi.org/10.1101/2022.03.16.484565
https://doi.org/10.1101/2022.03.16.484565