Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Jakub Toczek"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 827 (2024)
Endometriosis is an enigmatic disease, with no specific cause or trigger yet discovered. Major factors that may contribute to endometriosis in the pelvic region include environmental, epigenetic, and inflammatory factors. Most experts believe that th
Externí odkaz:
https://doaj.org/article/78b042890cf3479f96f9dfce1c08c39f
Autor:
Patrycja Wieczorek, Piotr Czekaj, Mateusz Król, Edyta Bogunia, Mateusz Hermyt, Emanuel Kolanko, Jakub Toczek, Aleksandra Skubis-Sikora, Aniela Grajoszek, Rafał Stojko
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 476 (2024)
The route of administration of implanted cells may affect the outcome of cell therapy by directing cell migration to the damaged site. However, the question of the relationship between the route of administration, the efficacy of colonisation of a gi
Externí odkaz:
https://doaj.org/article/82e110040fcd4412919daa516fd72650
Publikováno v:
Clinical and Experimental Obstetrics & Gynecology, Vol 49, Iss 7, p 153 (2022)
Objective: The aim of this study was to understand the pathophysiologic mechanisms of macrophage inflammatory protein 1 alpha (MIP1a) and beta (MIP1b) chemokines in endometriosis, and to understand the immuno-pathophysiology underlying the progressio
Externí odkaz:
https://doaj.org/article/a89688dde1554fe6b8771fc172cd4d48
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 679 (2022)
It is intractable to manage the vast majority of wounds in a classical surgical manner, however if silver, likewise gold and its representative nanoparticles, can lead to the amelioration of the wound healing process after extensive procedures, they
Externí odkaz:
https://doaj.org/article/f8587dfa0669459fa05cc242079ba757
Autor:
Yunpeng Ye, Jakub Toczek, Kiran Gona, Hye-Yeong Kim, Jinah Han, Mahmoud Razavian, Reza Golestani, Jiasheng Zhang, Terence L. Wu, Mousumi Ghosh, Jae-Joon Jung, Mehran M. Sadeghi
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Matrix metalloproteinases (MMPs) are involved in tissue remodeling. Accordingly, MMP inhibitors and related radiolabeled analogs are important tools for MMP-targeted imaging and therapy in a number of diseases. Herein, we report design, synt
Externí odkaz:
https://doaj.org/article/1e49a26ed93a4eedbdffd93fc7f56c2c
Publikováno v:
Artery Research, Vol 24 (2018)
Background: Matrix metalloproteinase-12 (MMP12) may modulate arterial stiffening with age [1]. We aimed to study the effect of aging on biaxial arterial stiffness in wild-type (WT) and MMP12 knock-out (MMP12-/-) mice. Methods and Results: After euth
Externí odkaz:
https://doaj.org/article/40aa15f67ff049cfa694ce50b7104b9e
Autor:
Jakub Toczek, Alexis Broisat, Pascale Perret, Marie-Dominique Desruet, Daniel Fagret, Laurent M Riou, Catherine Ghezzi
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e99441 (2014)
BACKGROUND:[18F]-fluorodeoxyglucose (FDG) has been suggested for the clinical and experimental imaging of inflammatory atherosclerotic lesions. Significant FDG uptake in brown adipose tissue (BAT) has been observed both in humans and mice. The object
Externí odkaz:
https://doaj.org/article/3cbd4c97c0f945e3a8992f61f5177180
Autor:
Mani Salarian, Mean Ghim, Jakub Toczek, Jinah Han, Dar Weiss, Bart Spronck, Abhay B. Ramachandra, Jae-Joon Jung, Gunjan Kukreja, Jiasheng Zhang, Deaneira Lakheram, Sung-Kwon Kim, Jay D. Humphrey, Mehran M. Sadeghi
Publikováno v:
Circulation Research. 132:432-448
Background: Matrix metalloproteinase (MMP)-12 is highly expressed in abdominal aortic aneurysms and its elastolytic function has been implicated in the pathogenesis. This concept is challenged, however, by conflicting data. Here, we sought to revisit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49efdcfa62e9cd72700c39e4042077b5
https://doi.org/10.1161/circresaha.122.322096
https://doi.org/10.1161/circresaha.122.322096
Autor:
Xinbo Zhang, Noemi Rotllan, Alberto Canfrán-Duque, Jonathan Sun, Jakub Toczek, Anna Moshnikova, Shipra Malik, Nathan L. Price, Elisa Araldi, Wen Zhong, Mehran M. Sadeghi, Oleg A. Andreev, Raman Bahal, Yana K. Reshetnyak, Yajaira Suárez, Carlos Fernández-Hernando
Publikováno v:
Circ Res
Background: miRNA therapeutics have gained attention during the past decade. These oligonucleotide treatments can modulate the expression of miRNAs in vivo and could be used to correct the imbalance of gene expression found in human diseases such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb733aafeaf7658bb00b0a0d274341d
https://doi.org/10.1161/circresaha.121.320296
https://doi.org/10.1161/circresaha.121.320296
Autor:
Jae-Joon Jung, Azmi A. Ahmad, Saranya Rajendran, Linyan Wei, Jiasheng Zhang, Jakub Toczek, Lei Nie, Gunjan Kukreja, Mani Salarian, Kiran Gona, Mean Ghim, Raja Chakraborty, Kathleen A. Martin, George Tellides, Donald Heistad, Mehran M. Sadeghi
Publikováno v:
JACC: Basic to Translational Science. 7:333-345
Expression of a neuropilin-like protein, DCBLD2, is reduced in human calcific aortic valve disease (CAVD). DCBLD2-deficient mice develop bicuspid aortic valve (BAV) and CAVD, which is more severe in BAV mice compared with tricuspid littermates. In vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab8d45661772b19d1803d0bc5338a40
https://doi.org/10.1016/j.jacbts.2021.12.006
https://doi.org/10.1016/j.jacbts.2021.12.006