Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jakub Tobiasz"'
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 234-245 (2020)
Elastin is a highly elastic protein present in connective tissue. As a result of protease activity, elastin hydrolysis occurs, and during this process, elastin-derived peptides (EDPs) are released. One of the constitutively repeating elastin and EDP
Externí odkaz:
https://doaj.org/article/06816bb92f4742088368391725974c7c
Autor:
Danylo Kaminskyy, Roman Lesyk, Marcin L. Leja, Jan Gmiński, Konrad A. Szychowski, Tadeusz Pomianek, Jakub Tobiasz, Maciej Wnuk, Anna Kryshchyshyn
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
4-thiazolidinones, which are privileged structures in medicinal chemistry, comprise the well-known class of heterocycles and are a source of new drug-like compounds. Undoubtedly, the 5-bulky-substituted-2,4-thiazolidinediones - a class of antihypergl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9f8be6e9f60f7d11e201b368525ada
https://doi.org/10.1038/s41598-019-47177-6
https://doi.org/10.1038/s41598-019-47177-6
Autor:
Jan Gmiński, Tadeusz Pomianek, Viktoriya Yelnytska-Stawasz, Kamila Rybczyńska-Tkaczyk, Konrad A. Szychowski, Jakub Tobiasz
Publikováno v:
Process Biochemistry. 73:180-187
Inonotus obliquus (IO) has traditionally been used in folk medicine in the treatment of gastrointestinal cancer, cardiovascular disease and diabetes. The aim of our study was to evaluate the biological and metabolic properties of IO extracts. Free ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93dd4c3ac621961f98f41c4eb99c8073
https://www.sciencedirect.com/journal/process-biochemistry/vol/73/suppl/C
https://www.sciencedirect.com/journal/process-biochemistry/vol/73/suppl/C
Autor:
Konrad A. Szychowski, Jan Gmiński, Jakub Tobiasz, Danylo Kaminskyy, Roman Lesyk, Bartosz Skóra, Anna Kryshchyshyn-Dylevych
Publikováno v:
Chemico-Biological Interactions. 345:109538
Nowadays, diabetes mellitus type 2 (T2DM) is a serious problem in western European societies and in the United States. Thiazolidinediones (TZDs) are a broad group of compounds used to decrease insulin resistance in TDM2. To date, it has been believed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a133da3cb1ed23a6c36f290cf65efdc9
https://doi.org/10.1016/j.cbi.2021.109538
https://doi.org/10.1016/j.cbi.2021.109538
Autor:
Konrad A. Szychowski, Anna Kryshchyshyn, Jakub Tobiasz, Urszula E. Binduga, O. R. Pinyazhko, Danylo Kaminskyy, Marcin L. Leja, Jan Gmiński, Roman Lesyk
Publikováno v:
European Journal of Medicinal Chemistry. 141:162-168
Peroxisome proliferator-activated receptors (PPARs) play an important role in numerous chronic diseases such as diabetes, obesity, atherosclerosis and cancer, and PPAR modulators are among the approved drugs and drug-candidates for their treatment. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f4ca77ce6abe3b880cd0f2846d6afe
https://www.sciencedirect.com/science/journal/02235234/141
https://www.sciencedirect.com/science/journal/02235234/141