Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jakub Styk"'
Autor:
Daniela Klimova, Jana Jakubechova, Ursula Altanerova, Andreas Nicodemou, Jakub Styk, Tomas Szemes, Vanda Repiska, Cestmir Altaner
Publikováno v:
Molecular and Cellular Probes, Vol 67, Iss , Pp 101894- (2023)
Extracellular vesicles (EVs) are nowadays a target of interest in cancer therapy as a successful drug delivering tool. Based on their many beneficial biocompatible properties are designed to transport nucleic acids, proteins, various nanomaterials or
Externí odkaz:
https://doaj.org/article/e691d83d1aaa4157a9e17588e7352ed5
Autor:
Gréta Gombos, Nikolett Németh, Ondrej Pös, Jakub Styk, Gergely Buglyó, Tomas Szemes, Ludovit Danihel, Bálint Nagy, István Balogh, Beáta Soltész
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1904 (2023)
Exosomes have the potential to be the future of personalized diagnostics and therapy. They are nano-sized particles between 30 and 100 nm flowing in the extracellular milieu, where they mediate cell–cell communication and participate in immune syst
Externí odkaz:
https://doaj.org/article/fd226508b2e740a190aff05fb58d4739
Autor:
Ondrej Pös, Jakub Styk, Gergely Buglyó, Michal Zeman, Lydia Lukyova, Kamila Bernatova, Evelina Hrckova Turnova, Tomas Rendek, Ádám Csók, Vanda Repiska, Bálint Nagy, Tomas Szemes
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10520 (2023)
Colorectal cancer (CRC) has one of the highest incidences among all types of malignant diseases, affecting millions of people worldwide. It shows slow progression, making it preventable. However, this is not the case due to shortcomings in its diagno
Externí odkaz:
https://doaj.org/article/443ae22305524db1a9f1ed30d0af7253
Autor:
Gergely Buglyó, Jakub Styk, Ondrej Pös, Ádám Csók, Vanda Repiska, Beáta Soltész, Tomas Szemes, Bálint Nagy
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4284 (2022)
Lynch syndrome (LS) is an autosomal dominant inherited cancer predisposition disorder, which may manifest as colorectal cancer (CRC), endometrial cancer (EC) or other malignancies of the gastrointestinal and genitourinary tract as well as the skin an
Externí odkaz:
https://doaj.org/article/6cbe8811f5284e3c8f750ca1695b75a2
Autor:
Ondrej Pös, Jan Radvanszky, Jakub Styk, Zuzana Pös, Gergely Buglyó, Michal Kajsik, Jaroslav Budis, Bálint Nagy, Tomas Szemes
Publikováno v:
Applied Sciences, Vol 11, Iss 2, p 819 (2021)
Gains and losses of large segments of genomic DNA, known as copy number variants (CNVs) gained considerable interest in clinical diagnostics lately, as particular forms may lead to inherited genetic diseases. In recent decades, researchers developed
Externí odkaz:
https://doaj.org/article/388700c856d4454a9222658b30135c53
Autor:
Zuzana Pös, Ondrej Pös, Jakub Styk, Angelika Mocova, Lucia Strieskova, Jaroslav Budis, Ludevit Kadasi, Jan Radvanszky, Tomas Szemes
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8634 (2020)
Analyzes of cell-free nucleic acids (cfNAs) have shown huge potential in many biomedical applications, gradually entering several fields of research and everyday clinical care. Many biological properties of cfNAs can be informative to gain deeper ins
Externí odkaz:
https://doaj.org/article/a947574e6c3e48cabd2b66390b40d976
Autor:
Jakub Styk, Zuzana Pös, Ondrej Pös, Jan Radvanszky, Evelina Hrckova Turnova, Gergely Buglyó, Daniela Klimova, Jaroslav Budis, Vanda Repiska, Bálint Nagy, Tomas Szemes
Publikováno v:
EPMA Journal. 14:143-165
A form of genomic alteration called microsatellite instability (MSI) occurs in a class of tandem repeats (TRs) called microsatellites (MSs) or short tandem repeats (STRs) due to the failure of a post-replicative DNA mismatch repair (MMR) system. Trad
Autor:
Beáta Soltész, Ondrej Pös, Zuzana Wlachovska, Jaroslav Budis, Rastislav Hekel, Lucia Strieskova, Jana Bozenka Liptak, Werner Krampl, Jakub Styk, Nikolett Németh, Judit Sz Keserű, Adrienn Jenei, Gergely Buglyó, Álmos Klekner, Bálint Nagy, Tomas Szemes
Publikováno v:
Molecular and cellular probes. 66
Glioblastoma is the most common malignant tumor of the central nervous system (CNS) in adults. Glioblastoma cells show increased glucose consumption associated with poor prognosis. Since mitochondria play a crucial role in energy metabolism, mutation
Publikováno v:
Vnitrni lekarstvi. 67(E-5)
Acute myeloid leukemia (AML) is a highly heterogeneous subtype of leukemia, accounting for 25 % of childhood leukemias. By the presence of genetic mutations in hematopoietic/ progenitor stem cells, the bone marrow produces a large number of abnormal
Autor:
Jakub Styk, Gergely Buglyó, Ondrej Pös, Ádám Csók, Beáta Soltész, Peter Lukasz, Vanda Repiská, Bálint Nagy, Tomáš Szemes
Publikováno v:
Cancers. 14:3712
Colorectal cancer (CRC) is the 3rd most common malignant neoplasm worldwide, with more than two million new cases diagnosed yearly. Despite increasing efforts in screening, many cases are still diagnosed at a late stage, when mortality is high. This