Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Jakub Rok"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 521 (2024)
Melanins are biopolymeric pigments formed by a multi-step oxidation process of tyrosine in highly specialized cells called melanocytes. Melanin pigments are mainly found in the skin, iris, hair follicles, and inner ear. The photoprotective properties
Externí odkaz:
https://doaj.org/article/e7b78ff275cc46389e91966eba7bb847
Autor:
Marta Karkoszka, Jakub Rok, Zuzanna Rzepka, Klaudia Banach, Justyna Kowalska, Dorota Wrześniok
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1432 (2024)
Hypertension is known to be a multifactorial disease associated with abnormalities in neuroendocrine, metabolic, and hemodynamic systems. Poorly controlled hypertension causes more than one in eight premature deaths worldwide. Hydrochlorothiazide (HC
Externí odkaz:
https://doaj.org/article/db615dacde114270985d079d647510b6
Autor:
Jakub Rok, Justyna Kowalska, Zuzanna Rzepka, Dominika Stencel, Anna Skorek, Klaudia Banach, Dorota Wrześniok
Publikováno v:
Cells, Vol 12, Iss 12, p 1564 (2023)
High mortality, aggressiveness, and the relatively low effectiveness of therapy make melanoma the most dangerous of skin cancers. Previously published studies presented the promising therapeutic potential of minocycline, doxycycline, and chlortetracy
Externí odkaz:
https://doaj.org/article/bbcfd8ce06d740c6a948c489ce35b3f2
Publikováno v:
Cells, Vol 12, Iss 4, p 593 (2023)
Flavonoids exert many beneficial properties, such as anticancer activity. They were found to have chemopreventive effects hindering carcinogenesis, and also being able to affect processes important for cancer cell pathophysiology inhibiting its growt
Externí odkaz:
https://doaj.org/article/930ad4eb54cc402cbc39c769e1db16aa
Autor:
Jakub Rok
Publikováno v:
Studia Regionalne i Lokalne, Vol 2, Iss 80, Pp 5-21 (2020)
The study aims to explore the interrelation of perceived air pollution and objective air pollution in the context of various subjective wellbeing (SWB) measures. An original survey data is used, and matched with exogenous levels of PM2.5 pollution in
Externí odkaz:
https://doaj.org/article/709ad6849e0a4db182ce961386c3dd20
Autor:
Mikołaj Herbst, Jakub Rok
Publikováno v:
Studia Regionalne i Lokalne, Vol 4, Iss 78, Pp 5-27 (2020)
Celem niniejszego artykułu jest eksploracyjna analiza przestrzennej alokacji środków na kapitał ludzki na poziomie lokalnym w Polsce. W szczególności analiza ta dotyczy przestrzennej dystrybucji środków Programu Operacyjnego Kapitał Ludzki (
Externí odkaz:
https://doaj.org/article/af8c7d168ae742ac9a1ca778d131038f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2353 (2023)
Melanoma is still one of the most dangerous cancers. New methods of treatment are sought due to its high aggressiveness and the relatively low effectiveness of therapies. Tetracyclines are drugs exhibiting anticancer activity. Previous studies have a
Externí odkaz:
https://doaj.org/article/ab4a114d8de94d589b2c5d569ad75ca1
Publikováno v:
Cells, Vol 11, Iss 21, p 3408 (2022)
Cobalamin (vitamin B12) deficiency is one of the major factors causing degenerative changes in the nervous system and, thus, various neurological and psychiatric symptoms. The underlying cellular mechanism of this phenomenon is not yet fully understo
Externí odkaz:
https://doaj.org/article/700163d65c1d45ce957f723522e839f7
Autor:
Justyna Kowalska, Klaudia Banach, Zuzanna Rzepka, Jakub Rok, Marta Karkoszka, Dorota Wrześniok
Publikováno v:
Cells, Vol 11, Iss 12, p 1971 (2022)
Phototoxicity induced by antibiotics is a real problem in health care. The discontinuation of antibiotic therapy due to a phototoxic reaction can lead to the development of resistant strains. Fluoroquinolones are widely used antibiotics that exhibit
Externí odkaz:
https://doaj.org/article/05adcbb2cc88425fa4e708090576495d
Autor:
Marta Karkoszka, Jakub Rok, Klaudia Banach, Justyna Kowalska, Zuzanna Rzepka, Dorota Wrześniok
Publikováno v:
Molecules, Vol 27, Iss 13, p 4215 (2022)
Meloxicam (MLX), which belongs to the oxicam nonsteroidal anti-inflammatory drug derivatives, is an inhibitor of the cyclooxygenase-2 (COX-2) enzyme. Cutaneous adverse effects caused by interaction between UVA radiation and exogenous factors can mani
Externí odkaz:
https://doaj.org/article/985d12b18eba4e6da3a5cf51ab0a9d98