Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jakub Młokosiewicz"'
Autor:
Jarosław Kończak, Bartosz Janusz, Jakub Młokosiewicz, Tadeusz Satława, Sonia Wróbel, Paweł Dudzic, Konrad Krawczyk
Protein folding problem obtained a practical solution recently, owing to advances in deep learning. There are classes of proteins though, such as antibodies, that are structurally unique, where the general solution still lacks. In particular, the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2f28d84ff59c0c40f7e7e1c37ecf4e
https://doi.org/10.1101/2022.12.06.519288
https://doi.org/10.1101/2022.12.06.519288
Autor:
Wiktoria Wilman, Sonia Wróbel, Weronika Bielska, Piotr Deszynski, Paweł Dudzic, Igor Jaszczyszyn, Jędrzej Kaniewski, Jakub Młokosiewicz, Anahita Rouyan, Tadeusz Satława, Sandeep Kumar, Victor Greiff, Konrad Krawczyk
Publikováno v:
Briefings in Bioinformatics. 23
Antibodies are versatile molecular binders with an established and growing role as therapeutics. Computational approaches to developing and designing these molecules are being increasingly used to complement traditional lab-based processes. Nowadays,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c4a7c73c8212cbd0aa02cce955994d
https://doi.org/10.1093/bib/bbac267
https://doi.org/10.1093/bib/bbac267
Autor:
Jakub Młokosiewicz, Piotr Deszyński, Wiktoria Wilman, Konrad Krawczyk, Igor Jaszczyszyn, Aleksandr Kovaltsuk, Jacob D. Galson, Jinwoo Leem, Rajkumar Ganesan
Publikováno v:
Bioinformatics (Oxford, England). 38(9)
Motivation Rational design of therapeutic antibodies can be improved by harnessing the natural sequence diversity of these molecules. Our understanding of the diversity of antibodies has recently been greatly facilitated through the deposition of hun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5edcdf0a3b8e7b383994f51cf92121ba
https://pubmed.ncbi.nlm.nih.gov/35274671
https://pubmed.ncbi.nlm.nih.gov/35274671
Autor:
Piotr Deszyński, Konrad Krawczyk, Stefano Bonissone, Igor Jaszczyszyn, Adam Volanakis, Jakub Młokosiewicz, Natalie Castellana, Rajkumar Ganesan
Publikováno v:
Nucleic Acids Research
Nanobodies, a subclass of antibodies found in camelids, are versatile molecular binding scaffolds composed of a single polypeptide chain. The small size of nanobodies bestows multiple therapeutic advantages (stability, tumor penetration) with the fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49443003512c84806959babf7d6c4507
https://pubmed.ncbi.nlm.nih.gov/34747487
https://pubmed.ncbi.nlm.nih.gov/34747487
Autor:
Jakub Młokosiewicz, Rajkumar Ganesan, Piotr Deszyński, Stefano Bonissone, Igor Jaszczyszyn, Adam Volanakis, Konrad Krawczyk, Natalie Castellana
Nanobodies, a subclass of antibodies found in camelids, are a versatile molecular binding scaffold composed of a single polypeptide chain. The small size of nanobodies bestows multiple therapeutic advantages (stability, tumor penetration) with the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::305a6b1f156017b212aca081d4af770b
https://doi.org/10.1101/2021.08.04.21261581
https://doi.org/10.1101/2021.08.04.21261581