Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jakub Kaczor"'
Autor:
Joanna C. Dawes, Philip Webster, Barbara Iadarola, Claudia Garcia-Diaz, Marian Dore, Bruce J. Bolt, Hamlata Dewchand, Gopuraja Dharmalingam, Alex P. McLatchie, Jakub Kaczor, Juan J. Caceres, Alberto Paccanaro, Laurence Game, Simona Parrinello, Anthony G. Uren
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Ligation-mediated PCR protocols have diverse uses including the identification of integration sites of insertional mutagens, integrating vectors and naturally occurring mobile genetic elements. For approaches that employ NGS seque
Externí odkaz:
https://doaj.org/article/cdb46adc21fd43509b19e5cc6b2b40e7
Autor:
Philip Webster, Joanna C. Dawes, Hamlata Dewchand, Katalin Takacs, Barbara Iadarola, Bruce J. Bolt, Juan J. Caceres, Jakub Kaczor, Gopuraja Dharmalingam, Marian Dore, Laurence Game, Thomas Adejumo, James Elliott, Kikkeri Naresh, Mohammad Karimi, Katerina Rekopoulou, Ge Tan, Alberto Paccanaro, Anthony G. Uren
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Evidence implicating cancer drivers can be sparse when limited to clonal events. Here, the authors present a retrovirus driven in vivo lymphomagenesis time course including hundreds of thousands of subclonal mutations and demonstrate the utility of t
Externí odkaz:
https://doaj.org/article/3cbfb68852e24510a503042bbd7eab4d
Autor:
Philip Webster, Joanna C. Dawes, Hamlata Dewchand, Katalin Takacs, Barbara Iadarola, Bruce J. Bolt, Juan J. Caceres, Jakub Kaczor, Gopuraja Dharmalingam, Marian Dore, Laurence Game, Thomas Adejumo, James Elliott, Kikkeri Naresh, Mohammad Karimi, Katerina Rekopoulou, Ge Tan, Alberto Paccanaro, Anthony G. Uren
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in the hyperlink for the online repository http://mulvdb.org which was incorrectly given as http://mulv.lms.mrc.ac.uk. This has been corrected in both the PDF and HTML versions of the Article.
Externí odkaz:
https://doaj.org/article/13f0e2f1c53c4bfaa3ac86f199693739
Autor:
Juan J. Caceres, James I. Elliott, Anthony G. Uren, Jakub Kaczor, Bruce J. Bolt, Katerina Rekopoulou, Philip Webster, Mohammad M. Karimi, Kikkeri N. Naresh, Hamlata Dewchand, Marian Dore, Katalin Takacs, Ge Tan, Thomas Adejumo, Laurence Game, Barbara Iadarola, Gopuraja Dharmalingam, Joanna C. Dawes, Alberto Paccanaro
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Determining whether recurrent but rare cancer mutations are bona fide driver mutations remains a bottleneck in cancer research. Here we present the most comprehensive analysis of murine leukemia virus-driven lymphomagenesis produced to date, sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b5d1053372586c9c48ffcf78173d60
https://doaj.org/article/3cbfb68852e24510a503042bbd7eab4d
https://doaj.org/article/3cbfb68852e24510a503042bbd7eab4d
Autor:
Mohammad M. Karimi, James I. Elliott, Jakub Kaczor, Philip Webster, Hamlata Dewchand, Kikkeri N. Naresh, Juan J. Caceres, Gopuraja Dharmalingam, Anthony G. Uren, Thomas Adejumo, Ge Tan, Laurence Game, Bruce J. Bolt, Barbara Iadarola, Katerina Rekopoulou, Marian Dore, Katalin Takacs, Alberto Paccanaro, Joanna C. Dawes
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications
Nature Communications
Determining whether recurrent but rare cancer mutations are bona fide driver mutations remains a bottleneck in cancer research. Here we present the most comprehensive analysis of murine leukemia virus-driven lymphomagenesis produced to date, sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202e21fefb78d791d8af37371dfa5b73
https://doi.org/10.1038/s41467-019-09109-w
https://doi.org/10.1038/s41467-019-09109-w
Autor:
James I. Elliott, Laurence Game, Caceres Jj, Anthony G. Uren, Jakub Kaczor, Barbara Iadarola, Bruce J. Bolt, Kikkeri N. Naresh, Hamlata Dewchand, Philip Webster, Ge Tan, Joanna C. Dawes, Katalin Takacs, Alberto Paccanaro, Thomas Adejumo, Gopuraja Dharmalingam
Determining whether recurrent but rare cancer mutations are bona fide driver mutations remains a bottleneck in cancer research. Here we present the most comprehensive analysis of retrovirus driven lymphomagenesis produced to date, sequencing 700,000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8031ba903cf47c9625ed3b52f35bdd
https://doi.org/10.1101/157800
https://doi.org/10.1101/157800
Autor:
Nobuyuki Kato, Valérie Kappler, Daniela Flügel, Stefan Vollmer, Catherine Rolvering, Iris Behrmann, Jakub Kaczor, Claude Haan, Thomas Kietzmann
Publikováno v:
Hepatology. 50:253-260
The interleukin-6-type cytokine oncostatin M (OSM) acts via the Janus kinase/signal transducer and activator of transcription pathway as well as via activation of mitogen-activated protein kinases and is known to critically regulate processes such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec565452d3749db30f2b44eac26b0ff
https://doi.org/10.1002/hep.22928
https://doi.org/10.1002/hep.22928
Autor:
Claude Haan, Karoline Gäbler, Catherine Rolvering, Guy Berchem, Sergio Álvarez Méndez, Iris Behrmann, René Eulenfeld, Jakub Kaczor, Valérie Palissot
Publikováno v:
Journal of Cellular and Molecular Medicine
The Janus kinase 2 mutant V617F occurs with high frequency in myeloproliferative neoplasms. Further mutations affecting the Janus kinase family have been discovered mostly in leukaemias and in myeloproliferative neoplasms. Owing to their involvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a25eb3ba0dbb5231dcd3b0e63155d5
https://pubmed.ncbi.nlm.nih.gov/23301855
https://pubmed.ncbi.nlm.nih.gov/23301855
Autor:
Catherine Rolvering, Serge Haan, Iris Behrmann, Jakub Kaczor, T. Nocker, Stefan Wüller, Claude Haan
Publikováno v:
Oncogene. 28(34)
Recently, mutations in the gene of Janus kinase 2 (Jak2) were discovered in patients suffering from chronic myeloproliferative disorders (MPD) and leukemia. As suppressors of cytokine signaling (SOCS) proteins are potent feedback inhibitors of Jak-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324850bfa55b165c558953f85c1cbf91
https://pubmed.ncbi.nlm.nih.gov/19543316
https://pubmed.ncbi.nlm.nih.gov/19543316
Autor:
Catherine Rolvering, Iris Behrmann, Valérie Kappler, Stefan Vollmer, Claude Haan, Daniela Flügel, Nobuyuki Kato, Jakub Kaczor, Thomas Kietzmann
Publikováno v:
Cytokine. 52:32-33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9226cd76201459a84cebd88fa0d0aabc
https://doi.org/10.1016/j.cyto.2010.07.145
https://doi.org/10.1016/j.cyto.2010.07.145