Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jakub Horňák"'
Autor:
Antonín Brisuda, James C. S. Ho, Pancham S. Kandiyal, Justin T-Y. Ng, Ines Ambite, Daniel S. C. Butler, Jaromir Háček, Murphy Lam Yim Wan, Thi Hien Tran, Aftab Nadeem, Tuan Hiep Tran, Anna Hastings, Petter Storm, Daniel L. Fortunati, Parisa Esmaeili, Hana Novotna, Jakub Horňák, Y. G. Mu, K. H. Mok, Marek Babjuk, Catharina Svanborg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Partially unfolded alpha-lactalbumin forms an oleic acid complex with antitumorigenic properties. Here, the authors define a structurally flexible, peptide-based oleate complex and report a phase I/II clinical trial where this complex is used to trea
Externí odkaz:
https://doaj.org/article/8bab807c461e46258408ec0d77b8d766
Publikováno v:
Current Opinion in Urology. 33:152-156
Autor:
Thi Hien Tran, Petter Storm, Kenneth Hun Mok, Antonin Brisuda, Catharina Svanborg, Anna Hastings, Justin Tze Yang Ng, Murphy Lam Yim Wan, Marek Babjuk, Pancham S. Kandiyal, Tuan Hiep Tran, James C. S. Ho, Hana Novotna, Daniel S.C. Butler, Yuguang Mu, Jaromir Hacek, Jakub Horňák, Aftab Nadeem, Ines Ambite, Daniel L. Fortunati, Parisa Esmaeili
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Partially unfolded alpha-lactalbumin forms the oleic acid complex HAMLET, with potent tumoricidal activity. Here we define a peptide-based molecular approach for targeting and killing tumor cells, and evidence of its clinical potential (ClinicalTrial