Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jakub Flasz"'
Autor:
Timothy W. Gorman, Benedicte Lallemand, Malcolm MacCoss, Michael C. Willis, Christopher J. Schofield, José L. Castro, Alistair J. M. Farley, Darren J. Dixon, Martin D. Smith, Bryony L. Elbert, Tarn C. Johnson, Jakub Flasz, Christophe Genicot, Robert S. Paton, Patrick Pasau
Publikováno v:
Chemical Science. 9(3)
Sulfones feature prominently in biologically active molecules and are key functional groups for organic synthesis. We report a mild, photoredox-catalyzed reaction for sulfonylation of aniline derivatives with sulfinate salts, and demonstrate the util
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27ec42762c5cef363b2b4cc0470f697
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Publikováno v:
Bioorganic Chemistry. 37:77-83
We present the synthesis of 1-thioglycosyl derivatives of uridine, which were designed to act as potential donor substrates for glycosyltransferases. We constructed such analogs using 5-amino-2-pyridyl 1-thioglycosides as glycosyl units which were co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560d86a04dcb0ce1faf6d0de3661fbb4
https://doi.org/10.1016/j.bioorg.2009.04.002
https://doi.org/10.1016/j.bioorg.2009.04.002
Autor:
Elbert, Bryony L.1, Farley, Alistair J. M.1, Gorman, Timothy W.1, Johnson, Tarn C.1, Genicot, Christophe2, Lallemand, Bénédicte2, Pasau, Patrick2, Flasz, Jakub3, Castro, José L.3, MacCoss, Malcolm4, Paton, Robert S.1 robert.paton@chem.ox.ac.uk, Schofield, Christopher J.1 christopher.schofield@chem.ox.ac.uk, Smith, Martin D.1 martin.smith@chem.ox.ac.uk, Willis, Michael C.1 michael.willis@chem.ox.ac.uk, Dixon, Darren J.1 darren.dixon@chem.ox.ac.uk
Publikováno v:
Chemistry - A European Journal. 10/20/2017, Vol. 23 Issue 59, p14733-14737. 5p.
Autor:
Johnson, Tarn C., Elbert, Bryony L., Farley, Alistair J. M., Gorman, Timothy W., Genicot, Christophe, Lallemand, Bénédicte, Pasau, Patrick, Flasz, Jakub, Castro, José L., MacCoss, Malcolm, Dixon, Darren J., Paton, Robert S., Schofield, Christopher J., Smith, Martin D., Willis, Michael C.
Publikováno v:
Chemical Science; 1/21/2018, Vol. 9 Issue 3, p629-633, 5p
Autor:
Matt Helm, Elias Arkoudis, Caroline Hughes, Jakub T. Flasz, Ewa Odrzywol, Colin O'Dowd, Gerald Gavory, Natalie Page, Eamon Cassidy, Keeva McClelland, Hugues Miel, Oliver Barker, Tim Harrison, Anthony Dossang
Publikováno v:
Cancer Research. 78:4869-4869
Given the importance of USP7 in known oncogenic pathways and its emerging role in immuno-oncology, the identification of USP7 inhibitors has attracted considerable interest in the scientific community. However, despite substantial efforts over the pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::369e45d6c4c01955b51cd4bbf0a0f259
https://doi.org/10.1158/1538-7445.am2018-4869
https://doi.org/10.1158/1538-7445.am2018-4869
Autor:
Jakub T. Flasz, Stephanie Burton, Frank Burkamp, Iain James, Matt Helm, Colin O'Dowd, Oliver Barker, Ewa Odrzywol, Keeva McClelland, Gerald Gavory, Alan P. Brown, Elias Arkoudis, Tim Harrison
Publikováno v:
Cancer Research. 75:LB-257
Over the past decade, protein ubiquitination has emerged as an important post-translational modification with roles in a plethora of cellular processes, and dysregulation in the ubiquitin proteasome system pathway (UPS) has been implicated in multipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05d46589a6429d5b0307c038a417da84
https://doi.org/10.1158/1538-7445.am2015-lb-257
https://doi.org/10.1158/1538-7445.am2015-lb-257