Zobrazeno 1 - 10
of 424
pro vyhledávání: '"Jakub Fichna"'
Autor:
Marcin Sochal, Marta Ditmer, Aleksandra Tarasiuk-Zawadzka, Agata Binienda, Szymon Turkiewicz, Adam Wysokiński, Filip Franciszek Karuga, Piotr Białasiewicz, Jakub Fichna, Agata Gabryelska
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10445 (2024)
Deprivation of sleep (DS) and its effects on circadian rhythm gene expression are not well understood despite their influence on various physiological and psychological processes. This study aimed to elucidate the changes in the expression of circadi
Externí odkaz:
https://doaj.org/article/f5b1ac6c736f4a31b08e8d86e8af9f62
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 4, Pp 567-572 (2023)
The present work describes the protolytic properties of the sialorphin derivative (Pal-Lys- Lys-Gln-His-Asn-Pro-Arg) in an aqueous solution, at constant temperature 25.0 ± 0.1 °C and ionic strength 0.1 M (NaClO4), over the entire pH range. The over
Externí odkaz:
https://doaj.org/article/4a3f3f93b9f64f3eba61ccb613c974e6
Autor:
Marek Pająk, Magdalena Woźniczka, Mirosława Świątek, Bartłomiej Czerwiński, Jakub Włodarczyk, Jakub Fichna
Publikováno v:
Acta Poloniae Pharmaceutica, Vol 80, Iss 1, Pp 23-31 (2023)
The present work describes the complexation properties of two synthetic nucleosides (used as ligands), i.e. β-D-ribofuranoside-4-pyrimidinone (ribo) and β-D-deoxyribofuranoside-4-pyrimidinone (deoxy) with Ag(I) ions in aqueous solution. The stabili
Externí odkaz:
https://doaj.org/article/aba5f78586c9414296e930c113b4670d
Autor:
Marcin Włodarczyk, Jakub Włodarczyk, Kasper Maryńczak, Anna Waśniewska-Włodarczyk, Urszula Doboszewska, Piotr Wlaź, Łukasz Dziki, Jakub Fichna
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1501 (2024)
The cryptoglandular perianal fistula is a common benign anorectal disorder that is managed mainly with surgery and in some cases may be an extremely challenging condition. Perianal fistulas are often characterized by significantly decreased patient q
Externí odkaz:
https://doaj.org/article/2da9ce6514e749acbd4c5dc8838d888c
Publikováno v:
Molecules, Vol 29, Iss 1, p 90 (2023)
The present work describes the complexation of the anti-inflammatory sialorphin derivative Pal-Lys-Lys-Gln-His-Asn-Pro-Arg (palmitic acid-lysine-lysine-glutamine-histidine-asparagine-proline-arginine) with Cu(II) ions in an aqueous solution, at a tem
Externí odkaz:
https://doaj.org/article/136ac175c0864421b7ee7a458198a2b9
Autor:
Marcin Włodarczyk, Adam Makaro, Mateusz Prusisz, Jakub Włodarczyk, Marta Nowocień, Kasper Maryńczak, Jakub Fichna, Łukasz Dziki
Publikováno v:
Life, Vol 13, Iss 8, p 1692 (2023)
Crohn’s disease (CD) is a chronic, relapsing disorder belonging to inflammatory bowel diseases (IBD). It is manifested by relapsing transmural inflammation found in any segment of the gastrointestinal tract. Chronic fatigue is a common and underrec
Externí odkaz:
https://doaj.org/article/0fc439fdc94a4005ade1258e7ae7c334
Autor:
Jakub Włodarczyk, Julia Krajewska, Łukasz Szeleszczuk, Patrycja Szałwińska, Agata Gurba, Szymon Lipiec, Przemysław Taciak, Remigiusz Szczepaniak, Izabela Mlynarczuk-Bialy, Jakub Fichna
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7025 (2023)
Inflammatory bowel diseases (IBD) and their main representatives, Crohn’s disease and ulcerative colitis, are worldwide health-care problems with constantly increasing frequency and still not fully understood pathogenesis. IBD treatment involves dr
Externí odkaz:
https://doaj.org/article/893d25f8b9dc40d9b8a61776ba477273
Autor:
Marcin Sochal, Marta Ditmer, Agata Binienda, Agata Gabryelska, Piotr Białasiewicz, Renata Talar-Wojnarowska, Jakub Fichna, Ewa Małecka-Wojciesko
Publikováno v:
Metabolites, Vol 13, Iss 3, p 450 (2023)
Inflammatory bowel disease (IBD) patients often have sleep and mood disorders. Brain-derived neurotrophic factor (BDNF) and proBDNF were shown to modulate interactions between the central nervous system and the gastrointestinal tract, possibly contri
Externí odkaz:
https://doaj.org/article/fd2aa86830db412aa15f32bb2134e152
Autor:
Kai Xia, Renyuan Gao, Xiaocai Wu, Jing Sun, Jian Wan, Tianqi Wu, Jakub Fichna, Lu Yin, Chunqiu Chen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
BackgroundCrohn’s disease (CD) is a chronic nonspecific inflammatory bowel disease (IBD) with an increasing incidence worldwide. The etiology of CD is still obscure, but microbial dysbiosis has been recognized as an essential factor contributing to
Externí odkaz:
https://doaj.org/article/8801cbb4948c4d0cbf62b6454cefec5d
Publikováno v:
Cells, Vol 11, Iss 23, p 3876 (2022)
Adhesion G protein-coupled receptor F5 (ADGRF5) is involved inthe neoplastic transformation of some cancer types. However, the significance of ADGRF5 expression signature and the impact of signaling pathways mediated by ADGRF5 during neoplastic trans
Externí odkaz:
https://doaj.org/article/ac1a74069b9640a79ed50f5e852c5bcb