Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jakub Baudys"'
Autor:
Dongxia Wang, Bin Zhou, Theodore R. Keppel, Maria Solano, Jakub Baudys, Jason Goldstein, M. G. Finn, Xiaoyu Fan, Asheley P. Chapman, Jonathan L. Bundy, Adrian R. Woolfitt, Sarah H. Osman, James L. Pirkle, David E. Wentworth, John R. Barr
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract N-glycosylation plays an important role in the structure and function of membrane and secreted proteins. The spike protein on the surface of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, is
Externí odkaz:
https://doaj.org/article/94a2b1bf24dc4c3b9e141f9e202394e4
Publikováno v:
Toxins, Vol 7, Iss 5, Pp 1765-1778 (2015)
Botulinum neurotoxins (BoNTs) cause the disease called botulism, which can be lethal. BoNTs are proteins secreted by some species of clostridia and are known to cause paralysis by interfering with nerve impulse transmission. Although the human lethal
Externí odkaz:
https://doaj.org/article/120725c17dd747788dc4045bbdeb0a86
Publikováno v:
Toxins, Vol 9, Iss 6, p 193 (2017)
Botulism is a disease involving intoxication with botulinum neurotoxins (BoNTs), toxic proteins produced by Clostridium botulinum and other clostridia. The 150 kDa neurotoxin is produced in conjunction with other proteins to form the botulinum progen
Externí odkaz:
https://doaj.org/article/15eb3dee1869411db240e3c64b816e40
Autor:
Suzanne R Kalb, Consuelo Garcia-Rodriguez, Jianlong Lou, Jakub Baudys, Theresa J Smith, James D Marks, Leonard A Smith, James L Pirkle, John R Barr
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12237 (2010)
Botulinum neurotoxins (BoNTs) are extremely potent toxins that are capable of causing respiratory failure leading to long-term intensive care or death. The best treatment for botulism includes serotype-specific antitoxins, which are most effective wh
Externí odkaz:
https://doaj.org/article/9caf32e0dd4847e3b0283cc991a9e87a
Autor:
Jonathan L. Bundy, John R. Barr, Jakub Baudys, Dongxia Wang, Theodore Keppel, Maria I. Solano
Publikováno v:
Analytical Chemistry
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a global pandemic of coronavirus disease 2019 (COVID-19). The spike protein expressed on the surface of this virus is highly glycosylated and plays an essential role during the p
Autor:
Asheley P. Chapman, Dongxia Wang, John R. Barr, Jakub Baudys, Maria I. Solano, Sarah H Osman, David E. Wentworth, Jason M. Goldstein, Bin Zhou, Adrian R. Woolfitt, M. G. Finn, Xiaoyu Fan, Jonathan L. Bundy, James L. Pirkle, Theodore Keppel
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
N-glycosylation plays an important role in the structure and function of membrane and secreted proteins. The spike protein on the surface of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, is heavily
Publikováno v:
Journal of Analytical Toxicology
Journal of Analytical Toxicology, 2020, 44 (2), pp.173-179. ⟨10.1093/jat/bkz044⟩
J Anal Toxicol
Journal of Analytical Toxicology, Oxford University Press (OUP): Policy F, 2020, 44 (2), pp.173-179. ⟨10.1093/jat/bkz044⟩
Journal of Analytical Toxicology, 2020, 44 (2), pp.173-179. ⟨10.1093/jat/bkz044⟩
J Anal Toxicol
Journal of Analytical Toxicology, Oxford University Press (OUP): Policy F, 2020, 44 (2), pp.173-179. ⟨10.1093/jat/bkz044⟩
Botulinum neurotoxins (BoNTs) are a family of protein toxins consisting of seven known serotypes (BoNT/A—BoNT/G) and multiple subtypes within the serotypes, and all of which cause the disease botulism—a disease of great public health concern. Acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d108fcdeaa92d05dc61db029e34b4f96
https://hal.inrae.fr/hal-03350416
https://hal.inrae.fr/hal-03350416
Publikováno v:
Analytical and Bioanalytical Chemistry
Rapid and sensitive detection of botulinum neurotoxins (BoNTs), which cause botulism, is essential in a public health emergency or bioterrorism event. We have previously developed a mass spectrometry (MS)-based functional method, Endopep-MS assay, fo
Sensitive detection of type G botulinum neurotoxin through Endopep-MS peptide substrate optimization
Publikováno v:
Analytical and Bioanalytical Chemistry
Clostridium botulinum produces botulinum neurotoxins (BoNTs) that are one of the most poisonous substances. In order to respond to public health emergencies, there is a need to develop sensitive and specific methods for detecting botulinum toxin in v
Publikováno v:
Analytical Chemistry. 88:6867-6872
Ricin is a highly toxic protein which causes cell death by blocking protein synthesis and is considered a potential bioterrorism agent. Rapid and sensitive detection of ricin toxin in various types of sample matrices is needed as an emergency require