Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jakub Šimeček"'
Autor:
Jakub Šimeček, Petr Hermann, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Hans-Jürgen Wester, Johannes Notni
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-6 (2018)
Abstract Background The recently growing interest in targeted alpha-therapy (TAT) calls for improvement of the labelling chemistry of the corresponding radionuclides. 213BiIII is a short-lived alpha emitter which emits only one alpha particle in its
Externí odkaz:
https://doaj.org/article/495a2c35be444e1fa1e84e696a4d206b
Autor:
Gábor Máté, Jakub Šimeček, Miroslav Pniok, István Kertész, Johannes Notni, Hans-Jürgen Wester, László Galuska, Petr Hermann
Publikováno v:
Molecules, Vol 20, Iss 7, Pp 13112-13126 (2015)
In order to compare the coordination properties of 1,4,7-triazacyclononane (tacn) derivatives bearing varying numbers of phosphinic/carboxylic acid pendant groups towards 68Ga, 1,4,7-triazacyclononane-7-acetic-1,4-bis(methylenephosphinic) acid (NOPA)
Externí odkaz:
https://doaj.org/article/9b4d22bd044145f0bbc024366f270884
Autor:
Szandra Szilágyi, György Trencsényi, László Galuska, Gábor Máté, Jakub Šimeček, Dezso Szikra, István Kertész, Hans-Jürgen Wester
Publikováno v:
Journal of Flow Chemistry. 6:86-93
The synthesis and functional evaluation of a wide variety of radiolabeled chelator–biomolecule conjugates with high specific activity and radiochemical purity are crucial to development of personalized nuclear medicine. An excellent platform techno
Autor:
Sophie Poty, H. J. Wester, Franck Denat, Johannes Notni, Jakub Šimeček, Victor Goncalves, O. Raguin, Bertrand Collin, Christine Goze, Mathieu Moreau, Claire Bernhard, Pauline Désogère, François Brunotte, Frédéric Boschetti
Publikováno v:
Nuclear Medicine and Biology. :S11-S12
Autor:
Johannes Notni, István Kertész, László Galuska, Gábor Máté, Miroslav Pniok, Hans-Jürgen Wester, Petr Hermann, Jakub Šimeček
Publikováno v:
Molecules
Volume 20
Issue 7
Pages 13112-13126
Molecules, Vol 20, Iss 7, Pp 13112-13126 (2015)
Volume 20
Issue 7
Pages 13112-13126
Molecules, Vol 20, Iss 7, Pp 13112-13126 (2015)
In order to compare the coordination properties of 1,4,7-triazacyclononane (tacn) derivatives bearing varying numbers of phosphinic/carboxylic acid pendant groups towards 68Ga, 1,4,7-triazacyclononane-7-acetic-1,4-bis(methylenephosphinic) acid (NOPA)
Autor:
Martina Weineisen, Matthias Eiber, Akin Yildiz, Jakub Šimeček, Hans-Jürgen Wester, Michael Lassmann, Markus Schwaiger, Seval Beykan, Margret Schottelius, Ingo Klette, Richard P. Baum, Harshad R. Kulkarni
Publikováno v:
Journal of Nuclear Medicine. 56:1169-1176
On the basis of the high and consistent expression of prostate-specific membrane antigen (PSMA) in metastatic prostate cancer (PC), the goal of this study was the development, preclinical evaluation, and first proof-of-concept investigation of a PSMA
Autor:
Hans Wester, Jakub Šimeček, Christine Goze, Frédéric Boschetti, Franck Denat, Claire Bernhard, Sophie Poty, Pauline Désogère, Victor Goncalves, Johannes Notni
Publikováno v:
ChemMedChem. 10:1475-1479
In the past few years, gallium-68 has demonstrated significant potential as a radioisotope for positron emission tomography (PET), and the optimization of chelators for gallium coordination is a major goal in the development of radiopharmaceuticals.
Publikováno v:
Molecular Pharmaceutics. 11:3893-3903
The bifunctional chelator NOPO (1,4,7-triazacyclononane-1,4-bis[methylene(hydroxymethyl)phosphinic acid]-7-[methylene(2-carboxyethyl)phosphinic acid]) shows remarkably high Ga(III) complexation efficiency and comprises one carboxylic acid moiety whic
Publikováno v:
Radiochimica Acta. 99:293-300
The effect of solvent on nucleophilic substitution with cyclotron-produced [18F]fluoride was studied in polar aprotic (CH3CN and DMF) and protic solvent (t-BuOH andt-amyl alcohol) mixtures (CH3CN/co-solvent, 2:8) in a series of model compounds, 4-(R1
Autor:
Margret Schottelius, Michael Lassmann, Markus Schwaiger, Jakub Šimeček, Hans-Jürgen Wester, Ambros J. Beer, Ken Herrmann, Natalia S. Pellegata, Martina Rudelius, Kathrin Philipp-Abbrederis, Ulrich Keller, Frauke Hoffmann, Carlos Gerngross, Horst Kessler
Publikováno v:
Theranostics 5, 618-630 (2015)
Theranostics
Theranostics
Chemokine ligand-receptor interactions play a pivotal role in cell attraction and cellular trafficking, both in normal tissue homeostasis and in disease. In cancer, chemokine receptor-4 (CXCR4) expression is an adverse prognostic factor. Early clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44588de8f8503cdefc6c7f47a6e354d4
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=43851
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=43851