Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jakub, Otahal"'
Autor:
Petra Janovska, Petr Zouhar, Kristina Bardova, Jakub Otahal, Marek Vrbacky, Tomas Mracek, Katerina Adamcova, Lucie Lenkova, Jiri Funda, Tomas Cajka, Zdenek Drahota, Sara Stanic, Arild C. Rustan, Olga Horakova, Josef Houstek, Martin Rossmeisl, Jan Kopecky
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101683- (2023)
Objective: Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and energy homeostasis. Other mech
Externí odkaz:
https://doaj.org/article/31f0b59f9117425794b61598c518ae9c
Autor:
Tomas Petrasek, Iveta Vojtechova, Ondrej Klovrza, Klara Tuckova, Cestmir Vejmola, Jakub Rak, Anna Sulakova, Daniel Kaping, Nadine Bernhardt, Petrus J. de Vries, Jakub Otahal, Robert Waltereit
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background Tuberous sclerosis complex (TSC), a multi-system genetic disorder often associated with autism spectrum disorder (ASD), is caused by mutations of TSC1 or TSC2, which lead to constitutive overactivation of mammalian target of rapam
Externí odkaz:
https://doaj.org/article/104950206a9247428bf829602f54418e
Autor:
Jan Kudlacek, Jan Chvojka, Vojtech Kumpost, Barbora Hermanovska, Antonin Posusta, John G.R. Jefferys, Matias I. Maturana, Ondrej Novak, Mark J. Cook, Jakub Otahal, Jaroslav Hlinka, Premysl Jiruska
Publikováno v:
Neurobiology of Disease, Vol 159, Iss , Pp 105484- (2021)
Externí odkaz:
https://doaj.org/article/bd9f3851979241f4968393016754b423
Autor:
Jan Kudlacek, Jan Chvojka, Vojtech Kumpost, Barbora Hermanovska, Antonin Posusta, John G.R. Jefferys, Matias I. Maturana, Ondrej Novak, Mark J. Cook, Jakub Otahal, Jaroslav Hlinka, Premysl Jiruska
Publikováno v:
Neurobiology of Disease, Vol 154, Iss , Pp 105347- (2021)
The seemingly random and unpredictable nature of seizures is a major debilitating factor for people with epilepsy. An increasing body of evidence demonstrates that the epileptic brain exhibits long-term fluctuations in seizure susceptibility, and sei
Externí odkaz:
https://doaj.org/article/3dd96ecf581d4a17b9d132a4cb57295b
Autor:
Jan Kudlacek, Jan Chvojka, Antonin Posusta, Lubica Kovacova, Seung Bong Hong, Shennan Weiss, Kamila Volna, Petr Marusic, Jakub Otahal, Premysl Jiruska
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
Pathological high-frequency oscillations are a novel marker used to improve the delineation of epileptogenic tissue and, hence, the outcome of epilepsy surgery. Their practical clinical utilization is curtailed by the inability to discriminate them f
Externí odkaz:
https://doaj.org/article/964811433737441b8be85c004845472e
Autor:
Klara Tuckova, Cestmir Vejmola, Jakub Rak, Nadine Bernhardt, Tomas Petrasek, Iveta Vojtechova, Daniel Kaping, Jakub Otahal, Robert Waltereit, Petrus J. de Vries, Anna Sulakova, Ondrej Klovrza
Background: Tuberous Sclerosis Complex (TSC), a multi-system genetic disorder often associated with Autism Spectrum Disorder (ASD), is caused by mutations of TSC1 or TSC2, which lead to constitutive overactivation of mammalian Target of Rapamycin (mT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5489d24f1628a195f367df7067ba5362
https://doi.org/10.21203/rs.3.rs-122455/v1
https://doi.org/10.21203/rs.3.rs-122455/v1
Autor:
Jan Kudlacek, Jan Chvojka, Vojtech Kumpost, Barbora Hermanovska, Antonin Posusta, John G.R. Jefferys, Matias I. Maturana, Ondrej Novak, Mark J. Cook, Jakub Otahal, Jaroslav Hlinka, Premysl Jiruska
Publikováno v:
Neurobiology of Disease, Vol 154, Iss, Pp 105347-(2021)
The seemingly random and unpredictable nature of seizures is a major debilitating factor for people with epilepsy. An increasing body of evidence demonstrates that the epileptic brain exhibits long-term fluctuations in seizure susceptibility, and sei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f9a8453a89672f549f0ed81141e67ed0
https://pubmed.ncbi.nlm.nih.gov/34418569
https://pubmed.ncbi.nlm.nih.gov/34418569
Autor:
Wei-Chih, Chang, Jan, Kudlacek, Jaroslav, Hlinka, Jan, Chvojka, Michal, Hadrava, Vojtech, Kumpost, Andrew D, Powell, Radek, Janca, Matias I, Maturana, Philippa J, Karoly, Dean R, Freestone, Mark J, Cook, Milan, Palus, Jakub, Otahal, John G R, Jefferys, Premysl, Jiruska
Publikováno v:
Epilepsy Currents
Loss of Neuronal Network Resilience Precedes Seizures and Determines the Ictogenic Nature of Interictal Synaptic Perturbations Chang WC, Kudlacek J, Hlinka J, et al. Nat Neurosci. 2018; 21(12):1742-1752. doi:10.1038/s41593-018-0278-y. PMID: 30482946.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f06a644ed7de7af71f48abc8852de4cc
https://pubmed.ncbi.nlm.nih.gov/30955435
https://pubmed.ncbi.nlm.nih.gov/30955435
Publikováno v:
The European journal of neuroscience. 36(9)
We investigated the anticonvulsant and neurobiological effects of a highly selective neuronal nitric oxide synthase (nNOS) inhibitor, N (w) -propyl-l-arginine (L-NPA), on kainic acid (KA)-induced status epilepticus (SE) and early epileptogenesis in C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79665a54d454481b9da93b85deb9dc31
https://pubmed.ncbi.nlm.nih.gov/22943535
https://pubmed.ncbi.nlm.nih.gov/22943535
Autor:
Premysl, Jiruska, Martin, Tomasek, David, Netuka, Jakub, Otahal, John G R, Jefferys, Xiaoli, Li, Petr, Marusic
Publikováno v:
Epileptic disorders : international epilepsy journal with videotape. 10(3)
High-frequency activity has been described as having a role in the initiation of epileptic seizures. The case of a patient with refractory bitemporal epilepsy is presented. Extraoperative monitoring with depth and subdural electrodes revealed an icta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13d9f0bbe760f1ae8f1207bf4fe8aab0
https://pubmed.ncbi.nlm.nih.gov/18782695
https://pubmed.ncbi.nlm.nih.gov/18782695