Výsledky vyhledávání - "Jakobsen Martin R"

Akademický článek

HIV-1 predisposed to acquiring resistance to maraviroc (MVC) and other CCR5 antagonists in vitro has an inherent, low-level ability to utilize MVC-bound CCR5 for entry

Autor: Westby Mike, Jubb Becky, Salimiseyedabad Hamid, Ellett Anne, Jakobsen Martin R, Roche Michael, Lee Benhur, Lewin Sharon R, Churchill Melissa J, Gorry Paul R

Publikováno v: Retrovirology, Vol 8, Iss 1, p 89 (2011)

Abstract Background Maraviroc (MVC) and other CCR5 antagonists are HIV-1 entry inhibitors that bind to- and alter the conformation of CCR5, such that CCR5 is no longer recognized by the viral gp120 envelope (Env) glycoproteins. Resistance to CCR5 ant

Externí odkaz: https://doaj.org/article/6e99548c07164a1eac17830fbe4f1ed5

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Akademický článek

Single cell analysis reveals a subset of cytotoxic-like plasmacytoid dendritic cells in people with HIV-1

Autor: Cham, Lamin B., Gunst, Jesper D., Schleimann, Mariane H., Frattari, Giacomo S., Rosas-Umbert, Miriam, Vibholm, Line K., van der Sluis, Renée M., Jakobsen, Martin R., Olesen, Rikke, Lin, Lin, Tolstrup, Martin, Søgaard, Ole S.

Publikováno v: In iScience 15 September 2023 26(9)

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Akademický článek

Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites

Autor: Berkhout Ben, Wengel Jesper, Haasnoot Joost, Jakobsen Martin R, Kjems Jørgen

Publikováno v: Retrovirology, Vol 4, Iss 1, p 29 (2007)

Abstract Background A primary concern when targeting HIV-1 RNA by means of antisense related technologies is the accessibility of the targets. Using a library selection approach to define the most accessible sites for 20-mer oligonucleotides annealin

Externí odkaz: https://doaj.org/article/2183bdbec6f440c8a654b1960592c8b0

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