Meta-epidemiologic study of risk of bias assessed by Cochrane tool 2.0 and intervention effect estimates in intensive care randomised clinical trials. A protocol for the MERIT project

Autor: Koster, TM, Gluud, C, Jakobsen, JC, Van Der Horst, ICC, Keus, F

Introduction Meta-epidemiological analyses have demonstrated that reported trial design characteristics (e.g. randomisation method) are associated with intervention effect estimates in randomised clinical trials, but none have systematically assessed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc99c4141bde799042062f8100f4821

Drug therapy versus placebo or usual care for comatose survivors of cardiac arrest; a systematic review with meta-analysis.

Autor: McGuigan PJ; Regional Intensive Care Unit, Royal Victoria Hospital, 274 Grosvenor Road, Belfast, UK; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, UK. Electronic address: Peter.mcguigan@belfasttrust.hscni.net., Pauley E; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, UK. Electronic address: ellen.pauley@live.co.uk., Eastwood G; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia; Department of Intensive Care, Austin Hospital, Heidelberg, Australia. Electronic address: glenn.eastwood@monash.edu., Hays LMC; University College Dublin Clinical Research Centre, St Vincent's University Hospital, Dublin, Ireland. Electronic address: leanne.hays@ucd.ie., Jakobsen JC; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Capital Region of Denmark, Denmark; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Denmark. Electronic address: janus.jakobsen@ctu.dk., Moseby-Knappe M; Clinical Sciences Lund, Lund University, Lund, Sweden; Neurology and Rehabilitation, Skåne University Hospital, Lund, Sweden. Electronic address: marion.moseby_knappe@med.lu.se., Nichol AD; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia; University College Dublin Clinical Research Centre, St Vincent's University Hospital, Dublin, Ireland; The Alfred Hospital, Melbourne, Australia. Electronic address: alistair.nichol@ucd.ie., Nielsen N; Clinical Sciences Lund, Lund University, Lund, Sweden; Department of Anesthesiology and Intensive Care Medicine, Helsingborg Hospital, Helsingborg, Sweden. Electronic address: niklas.nielsen@med.lu.se., Skrifvars MB; Department of Emergency Care and Services, University of Helsinki, Finland; Helsinki University Hospital, Helsinki, Finland. Electronic address: markus.skrifvars@hus.fi., Blackwood B; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, UK. Electronic address: b.blackwood@qub.ac.uk., McAuley DF; Regional Intensive Care Unit, Royal Victoria Hospital, 274 Grosvenor Road, Belfast, UK; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, UK. Electronic address: d.f.mcauley@qub.ac.uk.

Publikováno v: Resuscitation [Resuscitation] 2024 Nov 14; Vol. 205, pp. 110431. Date of Electronic Publication: 2024 Nov 14.

Detailed statistical analysis plan for a guided self-determination intervention versus an attention control for outpatients with type 2 diabetes in the randomised OVERCOME trial.

Autor: Mathiesen AS; Department of Nephrology and Endocrinology, Center for Cancer and Organ Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark. anne.sophie.mathiesen@regionh.dk.; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark. anne.sophie.mathiesen@regionh.dk.; The Interdisciplinary Research Unit of Women's, Children's and Families' Health, The Julie Marie Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark. anne.sophie.mathiesen@regionh.dk., Zoffmann V; The Interdisciplinary Research Unit of Women's, Children's and Families' Health, The Julie Marie Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.; Department of Public Health, Sector of Health Services Research, University of Copenhagen, Copenhagen, Denmark.; School of Nursing and Midwifery, Faculty of Health, Deakin University, Melbourne, Australia., Lindschou J; Centre for Clinical Intervention Research, Copenhagen Trial Unit, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark., Jakobsen JC; Centre for Clinical Intervention Research, Copenhagen Trial Unit, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, The Faculty of Heath Sciences, University of Southern Denmark, Odense, Denmark., Gluud C; Centre for Clinical Intervention Research, Copenhagen Trial Unit, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, The Faculty of Heath Sciences, University of Southern Denmark, Odense, Denmark., Olsen MH; Centre for Clinical Intervention Research, Copenhagen Trial Unit, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.; Department of Neuroanaesthesiology, The Neuroscience Centre, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark., Rasmussen B; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.; Department of Public Health, Sector of Health Services Research, University of Copenhagen, Copenhagen, Denmark.; School of Nursing and Midwifery, Faculty of Health, Deakin University, Melbourne, Australia., Marqvorsen EHS; The Interdisciplinary Research Unit of Women's, Children's and Families' Health, The Julie Marie Center, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark., Rothmann MJ; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.; School of Nursing and Midwifery, Faculty of Health, Deakin University, Melbourne, Australia.; Department of Clinical Research, Faculty of Health Science, University of Southern Denmark, Odense, Denmark.

Publikováno v: Trials [Trials] 2024 Nov 11; Vol. 25 (1), pp. 751. Date of Electronic Publication: 2024 Nov 11.

The risks of adverse events with venlafaxine for adults with major depressive disorder: a systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis.

Autor: Kamp CB; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen Ø, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Petersen JJ; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen Ø, Denmark., Faltermeier P; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen Ø, Denmark.; MSH Medical School Hamburg, University of Applied Sciences and Medical University, Hamburg, Germany., Juul S; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen Ø, Denmark.; Stolpegaard Psychotherapy Centre, Mental Health Services in the Capital Region of Denmark, Gentofte, Denmark.; Department of Psychology, University of Copenhagen, Copenhagen, Denmark., Siddiqui F; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen Ø, Denmark., Moncrieff J; Division of Psychiatry, University College London, London, UK.; Research and Development Department, North East London NHS Foundation Trust (NELFT), London, UK., Horowitz MA; Division of Psychiatry, University College London, London, UK.; Research and Development Department, North East London NHS Foundation Trust (NELFT), London, UK., Hengartner MP; Department of Applied Psychology, Zurich University of Applied SciencesZurich, Switzerland., Kirsch I; Program in Placebo Studies, Harvard Medical School, Boston, MA, USA., Gluud C; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen Ø, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Jakobsen JC; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital - Rigshospitalet, Copenhagen Ø, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.

Publikováno v: Epidemiology and psychiatric sciences [Epidemiol Psychiatr Sci] 2024 Oct 23; Vol. 33, pp. e51. Date of Electronic Publication: 2024 Oct 23.

Hypothermia versus normothermia in patients with cardiac arrest and shockable rhythm: a secondary analysis of the TTM-2 study.

Autor: Taccone FS; Department of Intensive Care, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles (ULB), Brussels, Belgium. fabio.taccone@ulb.be.; After ROSC Network, Paris, France. fabio.taccone@ulb.be.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy. fabio.taccone@ulb.be., Cariou A; After ROSC Network, Paris, France.; Medical Intensive Care Unit, AP-HP Centre, Cochin Hospital, Université Paris Cité, Paris, France.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy., Zorzi S; Department of Intensive Care, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles (ULB), Brussels, Belgium.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy., Friberg H; Department of Clinical Sciences, Anesthesiology and Intensive Care, Lund University, Lund, Sweden.; Intensive and Perioperative Care, Skåne University Hospital, Malmö, Sweden.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy., Jakobsen JC; Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy., Nordberg P; Department of Clinical Science and Education, Center for Resuscitation Science, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy., Robba C; Department of Anesthesiology and Critical Care, IRCCS Policlinico San Martino, Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy., Belohlavek J; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; 2nd Department of Medicine, Cardiovascular Medicine, 1st Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic.; Institute for Heart Diseases, Wroclaw Medical University, Wrocław, Poland., Hovdenes J; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Oslo University Hospital, Rikshospitalet, Oslo, Norway., Haenggi M; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland., Åneman A; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Department of Intensive Care, Liverpool Hospital, Sydney, Australia., Grejs A; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Department of Intensive Care Medicine and Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Keeble TR; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Department of Cardiology, Essex Cardiothoracic Centre, MSE, Essex, UK.; Anglia Ruskin School of Medicine, MTRC, Chelmsford, UK., Annoni F; Department of Intensive Care, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles (ULB), Brussels, Belgium.; After ROSC Network, Paris, France.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy., Young PJ; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Department of Intensive Care, Wellington Regional Hospital, Te Whatu Ora, Capital, Coast and Hutt Valley, Wellington, New Zealand.; Medical Research Institute of New Zealand, Wellington, New Zealand.; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, VIC, Australia.; Department of Critical Care, University of Melbourne, Melbourne, VIC, Australia., Wise MP; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Adult Critical Care, University Hospital of Wales, Cardiff, UK., Cronberg T; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Department of Clinical Sciences, Department of Neurology, Skåne University Hospital Lund, Lund University, Lund, Sweden., Lilja G; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Department of Clinical Sciences, Anesthesiology and Intensive Care, Skåne University Hospital Lund, Lund University, Lund, Sweden., Nielsen N; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Department of Clinical Sciences, Anesthesiology and Intensive Care, Skåne University Hospital Lund, Lund University, Lund, Sweden., Dankiewicz J; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Cardiology Department, Lund University, Skåne University Hospital Lund, Lund, Sweden.

Publikováno v: Critical care (London, England) [Crit Care] 2024 Oct 15; Vol. 28 (1), pp. 335. Date of Electronic Publication: 2024 Oct 15.