Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jakob-Wendelin Genger"'
Autor:
Jasmina Panovska-Griffiths, Chris Griffiths, Andrea Siebenhofer, Christoph Bock, Werner Leber, Karin Stiasny, Oliver Lammel, Monika Redlberger-Fritz, Maria Elisabeth Mustafa-Korninger, Reingard Christina Glehr, Jeremy Camp, Benedikt Agerer, Alexander Lercher, Alexandra Popa, Jakob-Wendelin Genger, Thomas Penz, Stephan Aberle, Andreas Bergthaler, Eva-Maria Hochstrasser, Christian Hoellinger
Publikováno v:
BMJ Open, Vol 11, Iss 8 (2021)
Objectives We explore the importance of SARS-CoV-2 sentinel surveillance testing in primary care during a regional COVID-19 outbreak in Austria.Design Prospective cohort study.Setting A single sentinel practice serving 22 829 people in the ski-resort
Externí odkaz:
https://doaj.org/article/e01625da1827485099aa773e68ed83e3
Autor:
Shamsi Emtenani, Elliot T Martin, Attila Gyoergy, Julia Bicher, Jakob‐Wendelin Genger, Thomas Köcher, Maria Akhmanova, Mariana Guarda, Marko Roblek, Andreas Bergthaler, Thomas R Hurd, Prashanth Rangan, Daria E Siekhaus
Publikováno v:
The EMBO journal. 41(12)
Cellular metabolism must adapt to changing demands to enable homeostasis. During immune responses or cancer metastasis, cells leading migration into challenging environments require an energy boost, but what controls this capacity is unclear. Here, w
Autor:
Christoph Bock, Jakob-Wendelin Genger, Alexandra Popa, Andreas Bergthaler, Franziska Michor, Michael D. Nicholson, Lukas Endler
Publikováno v:
Sci Transl Med
Further analysis of SARS-CoV-2 genome sequencing data identifies several highly recurrent genetic variants with low allele frequencies, which, if filtered out, provide estimates consistent with tighter transmission bottlenecks.
Autor:
Alexandra Popa, Thomas Penz, Christoph Bock, Monika Redlberger-Fritz, Oliver Lammel, Eva-Maria Hochstrasser, Werner Leber, Reingard Christina Glehr, Andreas Bergthaler, Jeremy V. Camp, Karin Stiasny, Alexander Lercher, Stephan W. Aberle, Andrea Siebenhofer, Chris Griffiths, Christian Hoellinger, Jasmina Panovska-Griffiths, Maria Elisabeth Mustafa-Korninger, Jakob-Wendelin Genger, Benedikt Agerer
Publikováno v:
BMJ Open, Vol 11, Iss 8 (2021)
BMJ Open
BMJ Open
ObjectivesWe explore the importance of SARS-CoV-2 sentinel surveillance testing in primary care during a regional COVID-19 outbreak in Austria.DesignProspective cohort study.SettingA single sentinel practice serving 22 829 people in the ski-resort of
Autor:
Benedikt Agerer, Venugopal Gudipati, Maximilian Koblischke, Doris Trapin, Elisabeth Puchhammer-Stöckl, Thomas Penz, Mark J. Smyth, S. Wenda, Wolfgang Weninger, Jakob-Wendelin Genger, Winfried F. Pickl, Vanessa Mühlgrabner, Luis F Montano-Gutierrez, Stephan W. Aberle, Johannes B. Huppa, Ingrid Fae, Marianne Graninger, Marianna Traugott, Franz Allerberger, Matthias Farlik, Gottfried Fischer, Erich Pawelka, René Geyeregger, Hannes Stockinger, Florian Halbritter, Rudolf Valenta, Pia Gattinger, Lukas Endler, Wolfgang Hoepler, Anna-Maria Husa, Christoph Bock, Wolfgang Paster, Lisa Ellen Shaw, Judith H. Aberle, Alexandra Popa, David M. Florian, Volker Thiel, Daniele Barreca, Alexander Zoufaly, Alexander Lercher, Gernot Walder, Andreas Bergthaler, Ricard Torralba-Gombau
Publikováno v:
Science Immunology
CD8+ T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus control. Here, we identified nonsynonymous mutations in MHC-I-restricted CD8+ T cell epitopes after deep sequencing of 747 SARS-CoV-2 virus isolates. Mutant peptide
Autor:
Gottfried Fischer, Vanessa Muehlgrabner, Pia Gattinger, Venugopal Gudipati, Lukas Endler, Benedikt Agerer, Maximilian Koblischke, Thomas Penz, Erich Pawelka, Andreas Bergthaler, Alexander Zoufaly, Johannes B. Huppa, David M. Florian, Wolfgang Hoepler, Ingrid Fae, Alexander Lercher, Christoph Bock, Gernot Walder, Ricard Torralba-Gombau, Mark J. Smyth, S. Wenda, Rudolf Valenta, Jakob-Wendelin Genger, Judith H. Aberle, Marianna Traungott, Alexandra Popa
CD8+ T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus control, though direct evidence has been lacking so far. Here, we identified non-synonymous mutations in MHC-I restricted CD8+ T cell epitopes after deep sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19bf98b3e86de0d347370ff7748f7bfc
https://doi.org/10.1101/2020.12.18.423507
https://doi.org/10.1101/2020.12.18.423507
Autor:
Giulio Superti-Furga, Martin Senekowitsch, Mark J. Smyth, Michael Schuster, Thomas Penz, Franziska Michor, Franz Allerberger, Judith H. Aberle, Elisabeth Puchhammer-Stoeckl, Manfred Nairz, Wegene Borena, Mario Karolyi, Jakob-Wendelin Genger, Lukas Endler, Miguel L. Grau, Zsofia Keszei, Monika Redlberger-Fritz, Christoph Bock, Martin Borkovec, Dorothee von Laer, Henrique G. Colaço, Andreas Bergthaler, Michael T. Wolfinger, Michael D. Nicholson, Daniela Schmid, Erich Pawelka, Jan Laine, Benedikt Agerer, Alexander Zoufaly, Alexandra Popa, Stephan W. Aberle, Francisco Martinez Jimenez, Oriol Pich, Alexander Lercher, Guenter Weiss, Peter Hufnagl, Sabine Maritschnik, Nuria Lopez-Bigas
Superspreading events shape the COVID-19 pandemic. Here we provide a national-scale analysis of SARS-CoV-2 outbreaks in Austria, a country that played a major role for virus transmission across Europe and beyond. Capitalizing on a national epidemiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b17920f4c016bc09f8143916a24b1f4c
https://doi.org/10.1101/2020.07.15.204339
https://doi.org/10.1101/2020.07.15.204339
Autor:
Wegene Borena, Lukas Richter, Jakob-Wendelin Genger, Alexandra Popa, Franz Allerberger, Thomas Penz, Daniela Schmid, Andreas Bergthaler, Sabine Maritschnik, Christoph Bock, Peter Kreidl
Publikováno v:
Wiener Klinische Wochenschrift
Wiener klinische Wochenschrift
Wiener klinische Wochenschrift
SummaryThis is a report on the first identified cases of coronavirus disease 2019 (COVID-19) in Austria. The first documented case was a person who stayed in Kühtai, Tyrol, from 24 to 26 January 2020, and had been infected by a Chinese instructor in
Autor:
Jörg Menche, Hatoon Baazim, Bettina Gürtl, Andreas Bergthaler, Peter Májek, Burkhard Ludewig, Maria Ozsvar-Kozma, Gernot Schabbauer, Michael Caldera, Anannya Bhattacharya, Anna Orlova, Ulrich Kalinke, Lindsay Kosack, Daniela Reil, Julia S. Brunner, Natalia Pikor, Moritz F. Schlapansky, Paul N. Cheng, Jakob-Wendelin Genger, Dijana Vitko, Michael Trauner, Alexander Lercher, Keiryn L. Bennett, Richard Moriggl, Benedikt Agerer, Kristaps Klavins, Theresa Pinter, Alexandra Popa
Publikováno v:
Immunity
Summary Infections induce complex host responses linked to antiviral defense, inflammation, and tissue damage and repair. We hypothesized that the liver, as a central metabolic hub, may orchestrate systemic metabolic changes during infection. We infe
Autor:
Christoph Bock, Stephan W. Aberle, Michael Schuster, Thomas Penz, Monika Redlberger-Fritz, Lukas Endler, Sabine Maritschnik, Michael D. Nicholson, Francisco Martínez-Jiménez, Erich Pawelka, Giulio Superti-Furga, Jan Laine, Miguel L. Grau, Günter Weiss, Manfred Nairz, Judith H. Aberle, Andreas Bergthaler, Franziska Michor, Daniela Schmid, Dorothee von Laer, Martin Senekowitsch, Nuria Lopez-Bigas, Alexander Zoufaly, Mark J. Smyth, Peter Hufnagl, Mario Karolyi, Henrique G. Colaço, Wegene Borena, Jakob-Wendelin Genger, Alexander Lercher, Zsofia Keszei, Benedikt Agerer, Michael T. Wolfinger, Elisabeth Puchhammer-Stöckl, Martin Borkovec, Alexandra Popa, Oriol Pich, Franz Allerberger
Publikováno v:
Science Translational Medicine
Epidemiological and genomic analyses uncover viral mutational dynamics and transmission bottleneck size during the early COVID-19 pandemic in Austria.
Tracking and tracing SARS-CoV-2 mutations Austria was an early hotspot of SARS-CoV-2 transmiss
Tracking and tracing SARS-CoV-2 mutations Austria was an early hotspot of SARS-CoV-2 transmiss