Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jakob Wirbel"'
Autor:
Gaia Sambruni, Angeli D. Macandog, Jakob Wirbel, Danilo Cagnina, Carlotta Catozzi, Tiziano Dallavilla, Francesca Borgo, Nicola Fazio, Uberto Fumagalli-Romario, Wanda L. Petz, Teresa Manzo, Simona P. Ravenda, Georg Zeller, Luigi Nezi, Martin H. Schaefer
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background The association between microbes and cancer has been reported repeatedly; however, it is not clear if molecular tumour properties are connected to specific microbial colonisation patterns. This is due mainly to the current technic
Externí odkaz:
https://doaj.org/article/213f6dde22fd4445b062116b7522266d
Autor:
Hans-Joachim Ruscheweyh, Alessio Milanese, Lucas Paoli, Nicolai Karcher, Quentin Clayssen, Marisa Isabell Keller, Jakob Wirbel, Peer Bork, Daniel R. Mende, Georg Zeller, Shinichi Sunagawa
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Background Taxonomic profiling is a fundamental task in microbiome research that aims to detect and quantify the relative abundance of microorganisms in biological samples. Available methods using shotgun metagenomic data generally depend on
Externí odkaz:
https://doaj.org/article/7dcca887fbe548e4aa354361f2fc4c09
Autor:
Anne Kerstin Thomann, Torsten Wüstenberg, Jakob Wirbel, Laura-Louise Knoedler, Philipp Arthur Thomann, Georg Zeller, Matthias Philip Ebert, Stefanie Lis, Wolfgang Reindl
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Extraintestinal symptoms are common in inflammatory bowel diseases (IBD) and include depression and fatigue. These are highly prevalent especially in active disease, potentially due to inflammation-mediated changes in the microbio
Externí odkaz:
https://doaj.org/article/e9aa2f81853c459da1350817e225802c
Autor:
Solomon A. Sowah, Alessio Milanese, Ruth Schübel, Jakob Wirbel, Ece Kartal, Theron S. Johnson, Frank Hirche, Mirja Grafetstätter, Tobias Nonnenmacher, Romy Kirsten, Marina López-Nogueroles, Agustín Lahoz, Kathrin V. Schwarz, Jürgen G. Okun, Cornelia M. Ulrich, Johanna Nattenmüller, Arnold von Eckardstein, Daniel Müller, Gabriele I. Stangl, Rudolf Kaaks, Tilman Kühn, Georg Zeller
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-21 (2022)
Abstract Background The gut microbiota has been suggested to play a significant role in the development of overweight and obesity. However, the effects of calorie restriction on gut microbiota of overweight and obese adults, especially over longer du
Externí odkaz:
https://doaj.org/article/b2a9d6f5ed5d4fb9a3a65f3eb76bef31
Autor:
Marti Bernardo-Faura, Melanie Rinas, Jakob Wirbel, Inna Pertsovskaya, Vicky Pliaka, Dimitris E. Messinis, Gemma Vila, Theodore Sakellaropoulos, Wolfgang Faigle, Pernilla Stridh, Janina R. Behrens, Tomas Olsson, Roland Martin, Friedemann Paul, Leonidas G. Alexopoulos, Pablo Villoslada, Julio Saez-Rodriguez
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-16 (2021)
Abstract Background Multiple sclerosis (MS) is a major health problem, leading to a significant disability and patient suffering. Although chronic activation of the immune system is a hallmark of the disease, its pathogenesis is poorly understood, wh
Externí odkaz:
https://doaj.org/article/d0283f3687a1440293ae0739ffafff56
Autor:
Jakob Wirbel, Konrad Zych, Morgan Essex, Nicolai Karcher, Ece Kartal, Guillem Salazar, Peer Bork, Shinichi Sunagawa, Georg Zeller
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract The human microbiome is increasingly mined for diagnostic and therapeutic biomarkers using machine learning (ML). However, metagenomics-specific software is scarce, and overoptimistic evaluation and limited cross-study generalization are pre
Externí odkaz:
https://doaj.org/article/95e2803d50604883abc56458a1115172
Autor:
Daniel R. Garza, Rahwa Taddese, Jakob Wirbel, Georg Zeller, Annemarie Boleij, Martijn A. Huynen, Bas E. Dutilh
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-13 (2020)
Abstract Background Colorectal cancer (CRC) is a complex multifactorial disease. Increasing evidence suggests that the microbiome is involved in different stages of CRC initiation and progression. Beyond specific pro-oncogenic mechanisms found in pat
Externí odkaz:
https://doaj.org/article/aa3e05f63aa2450ca7b2b371b6e0b5a5
Autor:
Thomas SB Schmidt, Matthew R Hayward, Luis P Coelho, Simone S Li, Paul I Costea, Anita Y Voigt, Jakob Wirbel, Oleksandr M Maistrenko, Renato JC Alves, Emma Bergsten, Carine de Beaufort, Iradj Sobhani, Anna Heintz-Buschart, Shinichi Sunagawa, Georg Zeller, Paul Wilmes, Peer Bork
Publikováno v:
eLife, Vol 8 (2019)
The gastrointestinal tract is abundantly colonized by microbes, yet the translocation of oral species to the intestine is considered a rare aberrant event, and a hallmark of disease. By studying salivary and fecal microbial strain populations of 310
Externí odkaz:
https://doaj.org/article/64220b4d29ab449c874dab6b5a908fc4
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140805 (2015)
Malaria is a parasitic disease that causes severe hemolytic anemia in Plasmodium-infected hosts, which results in the release and accumulation of oxidized heme (hemin). Although hemin impairs the establishment of Plasmodium immunity in vitro and in v
Externí odkaz:
https://doaj.org/article/945ac076330a440db7f50095d569139e
Autor:
Rachael B. Chanin, Patrick T. West, Ryan M. Park, Jakob Wirbel, Gabriella Z. M. Green, Arjun M. Miklos, Matthew O. Gill, Angela S. Hickey, Erin F. Brooks, Ami S. Bhatt
Publikováno v:
bioRxiv
Bacterial populations that originate from a single bacterium are not strictly clonal. Often they contain subgroups that have distinct phenotypes. One way that bacteria generate this heterogeneity is through phase variation: enzyme-mediated, reversibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6873963eeaabb6f6bcda83ea732f63e7
https://doi.org/10.1101/2023.03.11.532203
https://doi.org/10.1101/2023.03.11.532203