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of 8
pro vyhledávání: '"Jakob Wallner"'
Autor:
Jakob Wallner, Krisztina Koczka, Karola Vorauer-Uhl, Lisa Nika, Reingard Grabherr, Dieter Palmberger
Publikováno v:
Protein Expression and Purification. 136:27-38
Biomarkers of cancer are often glycosylated membrane receptor proteins present on the cellular surface. In order to develop new antibodies for cancer diagnostics or treatment, it is a main pre-requisite that these target proteins are available in a n
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 154:186-194
Non-fluidic bio-layer interferometry (BLI) has rapidly become a standard tool for monitoring almost all biomolecular interactions in a label-free, real-time and high-throughput manner. High-efficiency screening methods which measure the kinetics of l
Autor:
Jakob Wallner, Bernhard Sissolak, Nico Lingg, Gerald Striedner, Wolfgang Sommeregger, Karola Vorauer-Uhl
Publikováno v:
Biotechnology Progress
Glycosylation, as the most prominent posttranslational modification, is recognized as an important quality attribute of monoclonal antibodies affected by various bioprocess parameters and cellular physiology. A method of lectin‐based bio‐layer in
Publikováno v:
Journal of Mathematical Chemistry. 52:575-587
For more than 50 years, optical biosensors have been used to measure bio-molecular interactions. The most frequently applied binding model to fit biosensor data is the simple 1:1 binding model which requires the stabilization of the association phase
Publikováno v:
Journal of Immunological Methods. 359:21-27
A new electrophoretic technique for the qualitative and quantitative analyses of IgM isoforms and fragments has been developed. IgMs which are more complex than many other recombinantly expressed immunoglobulins are characterized by their high molecu
Autor:
Jakob Wallner, Friedrich Altmann, Renate Kunert, Hermann Katinger, Willibald Steinfellner, Karola Vorauer-Uhl
Publikováno v:
Applied Microbiology and Biotechnology. 84:693-699
Protein-free media are gaining more and more interest in mammalian cell culture technology. However, the range of commercially available protein-free media is wide, but lack of serum causes the lack of various substances (Keenan et al. in Cytotechnol
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 119
Over the past few years, liposomal formulations as drug carrier systems have markedly advanced in pharmaceutical research and development. Therefore, analytical methods to characterize liposome-based formulations are required. One particular issue in
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 72
The development of biosensor technologies for the investigation of biomolecular interactions has markedly advanced over the last years. One promising biosensor platform, the Bio-Layer Interferometry (BLI), was developed by ForteBio with the main focu