Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Jakob Troppmair"'
Autor:
Andras T. Meszaros, Annemarie Weissenbacher, Melanie Schartner, Tim Egelseer-Bruendl, Martin Hermann, Jasmin Unterweger, Christa Mittelberger, Beatrix A. Reyer, Julia Hofmann, Bettina G. Zelger, Theresa Hautz, Thomas Resch, Christian Margreiter, Manuel Maglione, Timea Komlódi, Hanno Ulmer, Benno Cardini, Jakob Troppmair, Dietmar Öfner, Erich Gnaiger, Stefan Schneeberger, Rupert Oberhuber
Publikováno v:
Transplant International, Vol 37 (2024)
Donor organ biomarkers with sufficient predictive value in liver transplantation (LT) are lacking. We herein evaluate liver viability and mitochondrial bioenergetics for their predictive capacity towards the outcome in LT. We enrolled 43 consecutive
Externí odkaz:
https://doaj.org/article/0fa1744622fe42b993bcf6d4d4930586
Autor:
Florian Primavesi, Thomas Senoner, Sophie Schindler, Aleksandar Nikolajevic, Pietro Di Fazio, Georg Csukovich, Silvia Eller, Bettina Neumayer, Markus Anliker, Eva Braunwarth, Rupert Oberhuber, Thomas Resch, Manuel Maglione, Benno Cardini, Thomas Niederwieser, Silvia Gasteiger, Eckhard Klieser, Herbert Tilg, Stefan Schneeberger, Daniel Neureiter, Dietmar Öfner, Jakob Troppmair, Stefan Stättner
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 590 (2024)
Post-hepatectomy liver failure (PHLF) remains the major contributor to death after liver resection. Oxidative stress is associated with postoperative complications, but its impact on liver function is unclear. This first in-human, prospective, single
Externí odkaz:
https://doaj.org/article/d5da90c36d384f1ea045b7c1f7d7b7c9
Autor:
Andras T. Meszaros, Julia Hofmann, Madita L. Buch, Benno Cardini, Theresia Dunzendorfer-Matt, Florian Nardin, Michael J. Blumer, Margot Fodor, Martin Hermann, Bettina Zelger, Giorgi Otarashvili, Melanie Schartner, Annemarie Weissenbacher, Rupert Oberhuber, Thomas Resch, Jakob Troppmair, Dietmar ..fner, Heinz Zoller, Herbert Tilg, Erich Gnaiger, Theresa Hautz, Stefan Schneeberger
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104311- (2022)
Summary: Background: Reliable biomarkers for organ quality assessment during normothermic machine perfusion (NMP) are desired. ATP (adenosine triphosphate) production by oxidative phosphorylation plays a crucial role in the bioenergetic homeostasis o
Externí odkaz:
https://doaj.org/article/e529ae879efe4ad79d300a1b0ac02665
Autor:
Julia Hofmann, Andras T. Meszaros, Madita L. Buch, Florian Nardin, Verena Hackl, Carola J. Strolz, Bettina Zelger, Margot Fodor, Benno Cardini, Rupert Oberhuber, Thomas Resch, Annemarie Weissenbacher, Jakob Troppmair, Stefan Schneeberger, Theresa Hautz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9536 (2023)
The majority of organs used for liver transplantation come from brain-dead donors (DBD). In order to overcome the organ shortage, increasingly donation after circulatory death (DCD) organs are also considered. Since normothermic machine perfusion (NM
Externí odkaz:
https://doaj.org/article/d30526cf21bd4e32a3e3286c4e2ab235
Autor:
Franka Messner, Marco Thurner, Jule Müller, Michael Blumer, Julia Hofmann, Rainer Marksteiner, Sebastien Couillard-Despres, Jakob Troppmair, Dietmar Öfner, Stefan Schneeberger, Theresa Hautz
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background Muscle is severely affected by ischemia/reperfusion injury (IRI). Quiescent satellite cells differentiating into myogenic progenitor cells (MPC) possess a remarkable regenerative potential. We herein established a model of local a
Externí odkaz:
https://doaj.org/article/74a4fedf37974a51a18b663d56e42066
Novel, Innovative Models to Study Ischemia/Reperfusion-Related Redox Damage in Organ Transplantation
Autor:
Julia Hofmann, Marlene Pühringer, Sabrina Steinkellner, Aline-Sophie Holl, Andras T. Meszaros, Stefan Schneeberger, Jakob Troppmair, Theresa Hautz
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 31 (2022)
The implementation of ex vivo organ machine perfusion (MP) into clinical routine undoubtedly helped to increase the donor pool. It enables not just organ assessment, but potentially regeneration and treatment of marginal organs in the future. During
Externí odkaz:
https://doaj.org/article/79ac523de8e745a49113b840b2af5604
Autor:
Foroogh Mirzania, Mahdi Moridi Farimani, Yaghoub Sarrafi, Samad Nejad Ebrahimi, Jakob Troppmair, Marcel Kwiatkowski, Hermann Stuppner, Mostafa Alilou
Publikováno v:
Frontiers in Chemistry, Vol 9 (2022)
Phytochemical investigation on the acetone extract of Salvia mirzayanii Rech. f. and Esfand. afforded seven new isoprenoids including six new sesterterpenoids salvimirzacolide A-F (1–6), and one new nor-diterpenoid (7). Their structures were estab
Externí odkaz:
https://doaj.org/article/a6620a9a204841d49738c6f9199f0b9f
Autor:
Marco Thurner, Martin Deutsch, Katrin Janke, Franka Messner, Christina Kreutzer, Stanislav Beyl, Sébastien Couillard-Després, Steffen Hering, Jakob Troppmair, Rainer Marksteiner
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-17 (2020)
Abstract Background Degeneration of smooth muscles in sphincters can cause debilitating diseases such as fecal incontinence. Skeletal muscle-derived cells have been effectively used in clinics for the regeneration of the skeletal muscle sphincters, s
Externí odkaz:
https://doaj.org/article/dcc1b4dfa47d4f77bf9bbcc837b7b261
Publikováno v:
Molecular Oncology, Vol 12, Iss 6, Pp 869-882 (2018)
Metabolic reprogramming, as exemplified by the shift from oxidative phosphorylation to glycolysis, is a common feature of transformed cells. In many tumors, altered metabolism is also reflected in increased reactive oxygen species (ROS) levels, which
Externí odkaz:
https://doaj.org/article/1cead740927a4c9e9b5a4e9b1a241f7c
Autor:
Georg Gruenbacher, Hubert Gander, Andrea Rahm, Gabriele Dobler, Astrid Drasche, Jakob Troppmair, Walter Nussbaumer, Martin Thurnher
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The G protein-coupled P2Y11 receptor is known to sense extracellular ATP during inflammatory and immune responses. The dinucleotide NAD+ has also been proposed to be a P2Y11 receptor ligand but its role is less clear. Here, we have examined for the f
Externí odkaz:
https://doaj.org/article/f7527065a0d64848875bd47014568c8c