In situ high-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum

Autor: Jakob Toudahl Nielsen, Natalia V. Kulminskaya, Morten Bjerring, Juha M. Linnanto, Margus Rätsep, Marie Østergaard Pedersen, Petar H. Lambrev, Márta Dorogi, Győző Garab, Karen Thomsen, Caroline Jegerschöld, Niels-Ulrik Frigaard, Martin Lindahl, Niels Chr. Nielsen

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

The chlorosome of the photosynthetic bacterium C. tepidumharvests light and transfers the energy to the photosynthetic reaction centre. Here the authors determine the structure of the baseplate, a scaffolding super-structure, to show that the basepla

Externí odkaz: https://doaj.org/article/11b81cc89417464ab8b2b9a3f42d0f15

Using Topology to Estimate Structural Similarities of Proteins

Autor: Jørgen Ellegaard Andersen, Jens Ledet Jensen, Yuki Koyanagi, Jakob Toudahl Nielsen, Rasmus Villemoes

Publikováno v: Andersen, J E, Jensen, J L, Koyanagi, Y, Nielsen, J T & Villemoes, R 2021 ' Using Topology to Estimate Structural Similarities of Proteins ' arXiv.org . < https://arxiv.org/pdf/2111.14489 >
University of Southern Denmark

An effective model for protein structures is important for the study of protein geometry, which, to a large extent, determine the functions of proteins. There are a number of approaches for modelling; one might focus on the conformation of the backbo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1c2e568e380cc03b66c9ed2b18561c9f
https://findresearcher.sdu.dk:8443/ws/files/196104126/2111.14489v1.pdf

CheSPI: chemical shift secondary structure population inference

Autor: Jakob Toudahl, Nielsen, Frans A A, Mulder

Publikováno v: Journal of biomolecular NMR. 75(6-7)

NMR chemical shifts (CSs) are delicate reporters of local protein structure, and recent advances in random coil CS (RCCS) prediction and interpretation now offer the compelling prospect of inferring small populations of structure from small deviation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::83ddfd2c965292b0c7ae75b2ac91bd3c
https://pubmed.ncbi.nlm.nih.gov/34146207

Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

Autor: Erik B. Pedersen, Jakob Toudahl Nielsen, Claus Nielsen, Vyacheslav V. Filichev

Publikováno v: Nucleic Acids Research
Pedersen, E B, Nielsen, J T, Nielsen, C & Filichev, V V 2011, ' Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids ', Nucleic Acids Research, vol. 39, no. 6, pp. 2470-2481 . https://doi.org/10.1093/nar/gkq1133

Two G-quadruplex forming sequences, 5′-TGGGAG and the 17-mer sequence T30177, which exhibit anti-HIV-1 activity on cell lines, were modified using either locked nucleic acids (LNA) or via insertions of (R)-1-O-(pyren-1-ylmethyl)glycerol (intercalat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f09d2466b705afcd2e382ce6bdf1cc3
https://pubmed.ncbi.nlm.nih.gov/21062811

Optimal Control in NMR Spectroscopy: Implementation into SIMPSON and Novel Experiments for Biological Solid-State NMR

Autor: Cindie Kehlet, Zdenek Tosner, Anders Bodholt Nielsen, Morten Bjerring, Jakob Toudahl Nielsen, Mads Sloth Vinding, Thomas Vosegaard, Glaser, Steffen J., Navin Khaneja, Niels Chr. Nielsen

Publikováno v: Aarhus University
Kehlet, C, Tosner, Z, Nielsen, A B, Bjerring, M, Nielsen, J T, Vinding, M S, Vosegaard, T, Glaser, S J, Khaneja, N & Nielsen, N C 2009, ' Optimal Control in NMR Spectroscopy: Implementation into SIMPSON and Novel Experiments for Biological Solid-State NMR ', 50th Experimental NMR Conference (ENC), Asilomar, CA, United States, 29/03/2009-03/04/2009 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7073de1703cbc2544ee550fabaf2c2ca
https://pure.au.dk/portal/en/publications/optimal-control-in-nmr-spectroscopy-implementation-into-simpson-and-novel-experiments-for-biological-solidstate-nmr(c93e1620-1a1c-11df-b95d-000ea68e967b).html