Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jakob T, Sieker"'
Autor:
Meggin Q Costa, Martha M Murray, Jakob T Sieker, Naga Padmini Karamchedu, Benedikt L Proffen, Braden C Fleming
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256765 (2021)
Anterior cruciate ligament injuries result in posttraumatic osteoarthritis in the medial compartment of the knee, even after surgical treatment. How the chondrocyte distribution within the articular cartilage changes early in this process is currentl
Externí odkaz:
https://doaj.org/article/f7ad116c26bd40aaabeafefb3b5e7a44
Autor:
Ugur M Ayturk, Jakob T Sieker, Carla M Haslauer, Benedikt L Proffen, Manuela H Weissenberger, Matthew L Warman, Braden C Fleming, Martha M Murray
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229449 (2020)
Anterior cruciate ligament (ACL) transection surgery in the minipig induces post-traumatic osteoarthritis (PTOA) in a pattern similar to that seen in human patients after ACL injury. Prior studies have reported the presence of cartilage matrix-degrad
Externí odkaz:
https://doaj.org/article/4ca76b4b78344870a53cb8f3fc4af26e
Autor:
Ata M Kiapour, Jakob T Sieker, Benedikt L Proffen, TuKiet T Lam, Braden C Fleming, Martha M Murray
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212662 (2019)
Surgical transection of the anterior cruciate ligament (ACL) in the porcine model leads to posttraumatic osteoarthritis if left untreated. However, a recently developed surgical treatment, bridge-enhanced ACL repair, prevents further cartilage damage
Externí odkaz:
https://doaj.org/article/22d92fd719cd4d7290838995a8b1dae6
Autor:
Dominik John, Daniel G. Tobert, Elmar Herbst, Andreas Voss, Daniel Smolen, Philip P. Roessler, Björn Andreß, Jonas Pogorzelski, Jakob T. Sieker, Leo Pauzenberger
Publikováno v:
Knee Surgery, Sports Traumatology, Arthroscopy
Purpose The purpose of this study was to identify modifiable factors associated with research activity among residents working in orthopedic surgery and traumatology. Methods Residents at 796 university-affiliated hospitals in Austria, Germany, and S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daad4ffa350e95371f72f08a663119f8
https://doi.org/10.1007/s00167-020-05983-w
https://doi.org/10.1007/s00167-020-05983-w
Publikováno v:
British Journal of Haematology. 191:120-122
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76af4b79ec8d2b848a8ebea6b21cf8f9
https://doi.org/10.1111/bjh.16936
https://doi.org/10.1111/bjh.16936
Autor:
H Whetstone, Jakob T. Sieker, April M. Craft, O F Gardner, Gordon Keller, Y Nartiss, S C Juneja, Christian Veillette
Publikováno v:
European Cells & Materials, Vol 38, Pp 215-227 (2019)
In an effort to develop an effective source of clinically relevant cells and tissues for cartilage repair a directed differentiation method was used to generate articular chondrocytes and cartilage tissues from human embryonic stem cells (hESCs). It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66bb6ce9983f402bde5f7cfd6f69354
https://doi.org/10.22203/ecm.v038a15
https://doi.org/10.22203/ecm.v038a15
Autor:
Martha M. Murray, Naga Padmini Karamchedu, Braden C. Fleming, Meggin Q Costa, Gabriela Portilla, Benedikt L. Proffen, Janine Molino, Jakob T. Sieker
Publikováno v:
Am J Sports Med
Background: The extent of posttraumatic osteoarthritis (PTOA) in the porcine anterior cruciate ligament (ACL) transection model is dependent on the surgical treatment selected. In a previous study, animals treated with bridge-enhanced ACL repair usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17547404382534b0ac463418144d4801
https://pubmed.ncbi.nlm.nih.gov/33534613
https://pubmed.ncbi.nlm.nih.gov/33534613
Autor:
Coteia Pina, Gary L Horowitz, Ming Zhou, Arthur R. Rabson, Coby Horowitz, Cheng-Tsung K Hu, Meriane Lacombe-Daphnis, Bernadette Chirokas, Steven A. Bogen, Jakob T. Sieker, Nicholas E. Heger
Publikováno v:
The Journal of Applied Laboratory Medicine
Background Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcription PCR is the primary method to diagnose coronavirus disease 2019 (COVID-19). However, the analytic sensitivity required is not well defined an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a6b4f42c2d83630fddeb28d4e7a0fa
Autor:
Thomas Barthel, Christian Konrads, Manuela Kunz, Franz Jakob, Regina Ebert, Jakob T. Sieker, Patrick Prager, and Andre Steinert, Ludger Klein-Hitpass
Publikováno v:
Knee Surgery & Related Research
Purpose Mesenchymal stem cells (MSCs) isolated from the anterior cruciate ligament (ACL) share multiple characteristics of bone marrow-derived mesenchymal stem cells (BMSCs), allowing their use for regenerative therapies. Injuries to the ACL can affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2dc5b78a5e18eadfa9981fc4e16fcd
http://europepmc.org/articles/PMC6122945
http://europepmc.org/articles/PMC6122945
Autor:
Johannes Konrad, Martha M. Murray, Braden C. Fleming, Benedikt L. Proffen, Naga Padmini Karamchedu, Kaitlyn E. Chin, Ata M. Kiapour, Kimberly A. Waller, Gabriel S. Perrone, Matthew R. Akelman, Jakob T. Sieker
Publikováno v:
Journal of Orthopaedic Research®. 36:2128-2139
To determine the transcriptional profile of synovium during the molecular phase of post-traumatic osteoarthritis, anterior cruciate ligament transections (ACL) were performed in 36 Yucatan minipigs. Equal numbers were randomly assigned to no further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48085640e8715da328cf4c0d6d8e4984
https://doi.org/10.1002/jor.23876
https://doi.org/10.1002/jor.23876