Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jakob Steinfeldt"'
Autor:
Jakob Steinfeldt, Benjamin Wild, Thore Buergel, Maik Pietzner, Julius Upmeier zu Belzen, Andre Vauvelle, Stefan Hegselmann, Spiros Denaxas, Harry Hemingway, Claudia Langenberg, Ulf Landmesser, John Deanfield, Roland Eils
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The COVID-19 pandemic exposed a global deficiency of systematic, data-driven guidance to identify high-risk individuals. Here, we illustrate the utility of routinely recorded medical history to predict the risk for 1883 diseases across clini
Externí odkaz:
https://doaj.org/article/cf93c6a7e543471b8a87c26695b45644
Autor:
Jakob Steinfeldt, MD, Thore Buergel, MSc, Lukas Loock, MSc, Paul Kittner, BSc, Greg Ruyoga, Julius Upmeier zu Belzen, MSc, Simon Sasse, BSc, Henrik Strangalies, BSc, Lara Christmann, MSc, Noah Hollmann, BSc, Benedict Wolf, BSc, Brian Ference, ProfMD, John Deanfield, ProfMD, Ulf Landmesser, ProfMD, Roland Eils, ProfPhD
Publikováno v:
The Lancet: Digital Health, Vol 4, Iss 2, Pp e84-e94 (2022)
Summary: Background: In primary cardiovascular disease prevention, early identification of high-risk individuals is crucial. Genetic information allows for the stratification of genetic predispositions and lifetime risk of cardiovascular disease. How
Externí odkaz:
https://doaj.org/article/2b6f61e52191473b9f0c39c675338b85
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 8, p 87 (2021)
Induction of cardiomyocyte proliferation is a promising option to regenerate the heart. Thus, it is important to elucidate mechanisms that contribute to the cell cycle arrest of mammalian cardiomyocytes. Here, we assessed the contribution of the peri
Externí odkaz:
https://doaj.org/article/c11cf7aef8654b9e850e0c3d75ce59bc
Autor:
Thore Buergel, Jakob Steinfeldt, Greg Ruyoga, Maik Pietzner, Daniele Bizzarri, Dina Vojinovic, Julius Upmeier zu Belzen, Lukas Loock, Paul Kittner, Lara Christmann, Noah Hollmann, Henrik Strangalies, Jana M. Braunger, Benjamin Wild, Scott T. Chiesa, Joachim Spranger, Fabian Klostermann, Erik B. van den Akker, Stella Trompet, Simon P. Mooijaart, Naveed Sattar, J. Wouter Jukema, Birgit Lavrijssen, Maryam Kavousi, Mohsen Ghanbari, Mohammad A. Ikram, Eline Slagboom, Mika Kivimaki, Claudia Langenberg, John Deanfield, Roland Eils, Ulf Landmesser
Publikováno v:
Nature Medicine. NATURE PORTFOLIO
Nature Medicine
Nature Medicine, 28(11), 2309-2320. Nature Publishing Group
Nature Medicine, 28(11)
Nature Medicine
Nature Medicine, 28(11), 2309-2320. Nature Publishing Group
Nature Medicine, 28(11)
Publisher Copyright: © 2022, The Author(s). Risk stratification is critical for the early identification of high-risk individuals and disease prevention. Here we explored the potential of nuclear magnetic resonance (NMR) spectroscopy-derived metabol
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 8, Iss 87, p 87 (2021)
Journal of Cardiovascular Development and Disease
Volume 8
Issue 8
Pages: 87
Journal of Cardiovascular Development and Disease
Volume 8
Issue 8
Pages: 87
Induction of cardiomyocyte proliferation is a promising option to regenerate the heart. Thus, it is important to elucidate mechanisms that contribute to the cell cycle arrest of mammalian cardiomyocytes. Here, we assessed the contribution of the peri
Autor:
Sven Twardziok, Irina Lehmann, Sven Laudi, Johannes Liebig, Robert Lorenz Chua, Soeren Lukassen, Sarah Dorothea Müller, Bettina Heidecker, Marco Binder, Jennifer Loske, Martin Witzenrath, Florian Kurth, Christine Goffinet, Christina Klasa, Jan Philipp Albrecht, Teresa G Krieger, Uwe G. Liebert, Saskia Trump, Leif E. Sander, Loreen Thürmann, Julia Kazmierski, Sara Hadzibegovic, Thore Bürgel, Marey Messingschlager, Alessia Lena, Christian Drosten, Maria Theresa Völker, Victor M. Corman, Ulf Landmesser, Jürgen Eils, Markus S. Anker, Naveed Ishaque, Lars Kaderali, Roland Eils, Fabian Pott, Jakob Steinfeldt, Christian Conrad, Bianca P Hennig
Publikováno v:
Nature Biotechnology
In coronavirus disease 2019 (COVID-19), hypertension and cardiovascular diseases are major risk factors for critical disease progression. However, the underlying causes and the effects of the main anti-hypertensive therapies-angiotensin-converting en