Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jakob Schnabl"'
A Rapid, Highly Sensitive and Open-Access SARS-CoV-2 Detection Assay for Laboratory and Home Testing
Autor:
Max J. Kellner, James J. Ross, Jakob Schnabl, Marcus P. S. Dekens, Martin Matl, Robert Heinen, Irina Grishkovskaya, Benedikt Bauer, Johannes Stadlmann, Luis Menéndez-Arias, Andrew D. Straw, Robert Fritsche-Polanz, Marianna Traugott, Tamara Seitz, Alexander Zoufaly, Manuela Födinger, Christoph Wenisch, Johannes Zuber, Vienna COVID-19 Detection Initiative (VCDI), Andrea Pauli, Julius Brennecke
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
RT-qPCR-based diagnostic tests play important roles in combating virus-caused pandemics such as Covid-19. However, their dependence on sophisticated equipment and the associated costs often limits their widespread use. Loop-mediated isothermal amplif
Externí odkaz:
https://doaj.org/article/b9354072a8944c7594458f9ad554e747
Autor:
Özge Uluçkan, Maria Jiménez, Ben Roediger, Jakob Schnabl, Lucía T. Díez-Córdova, Kevin Troulé, Wolfgang Weninger, Erwin F. Wagner
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 844-859.e3 (2019)
Summary: Atopic dermatitis (AD) is a multi-factorial skin disease with a complex inflammatory signature including type 2 and type 17 activation. Although colonization by S. aureus is common in AD, the mechanisms rendering an organism prone to dysbios
Externí odkaz:
https://doaj.org/article/d5ac7b9f2732476597e255971c801fcd
Autor:
Lisa Baumgartner, Jakob Schnabl, Katharina Meixner, Veselin I. Andreev, Laszlo Tirian, Changwei Yu, Maria Novatchkova, Grzegorz Sienski, Peter Duchek, Dominik Handler, Julius Brennecke, Dinshaw J. Patel, Juncheng Wang, Maja Gehre
SUMMARYNuclear Argonaute proteins, guided by small RNAs, mediate sequence-specific heterochromatin formation. The molecular principles that link Argonaute-small RNA complexes to cellular heterochromatin effectors upon binding to nascent target RNAs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::906d13daf323bc8a5c86248e56f48460
https://doi.org/10.1101/2021.07.27.453956
https://doi.org/10.1101/2021.07.27.453956
Autor:
Veselin I. Andreev, Changwei Yu, Juncheng Wang, Jakob Schnabl, Laszlo Tirian, Maja Gehre, Dominik Handler, Peter Duchek, Maria Novatchkova, Lisa Baumgartner, Katharina Meixner, Grzegorz Sienski, Dinshaw J. Patel, Julius Brennecke
Publikováno v:
Nature Structural and Molecular Biology
Nuclear Argonaute proteins, guided by small RNAs, mediate sequence-specific heterochromatin formation. The molecular principles that link Argonaute-small RNA complexes to cellular heterochromatin effectors on binding to nascent target RNAs are poorly
Autor:
Julius Brennecke, Dominik Handler, Franz Allerberger, Peter Hufnagl, Max J Kellner, Martin Matl, Marcus P. S. Dekens, Julian J Ross, Robert Fritsche-Polanz, Manuela Foedinger, Johannes Zuber, Jakob Schnabl, Alexander Indra, Andrea Pauli, Justine Schaeffer, Robert Heinen
SUMMARYViral pandemics, such as Covid-19, pose serious threats to human societies. To control the spread of highly contagious viruses such as SARS-CoV-2, effective test-trace-isolate strategies require population-wide, systematic testing. Currently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b25b5de522ea2e7e8c45eccfe88065c5
https://doi.org/10.1101/2021.01.19.21250079
https://doi.org/10.1101/2021.01.19.21250079
Autor:
Peter Duchek, Kim Purkhauser, Maja Gehre, Nina Fasching, Jakob Schnabl, Maria Novatchkova, Julia Batki, Veselin I. Andreev, Juncheng Wang, Julius Brennecke, Dinshaw J. Patel, Ulrich Hohmann, Karl Mechtler, Clemens Plaschka
Nuclear Argonaute proteins, guided to nascent target RNAs by their bound small RNAs, elicit co-transcriptional silencing through heterochromatin formation at transposon insertions and repetitive genomic loci. The molecular mechanisms involved in this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404e28a6b762446de6c77093a5535df6
https://doi.org/10.1101/2021.01.08.425619
https://doi.org/10.1101/2021.01.08.425619
Autor:
Maria Novatchkova, Julia Batki, Kim Purkhauser, Julius Brennecke, Karl Mechtler, Dinshaw J. Patel, Ulrich Hohmann, Peter Duchek, Nina Fasching, Juncheng Wang, Clemens Plaschka, Veselin I. Andreev, Maja Gehre, Jakob Schnabl
Publikováno v:
Genes And Development
Genes Dev
Genes Dev
Nuclear Argonaute proteins, guided by their bound small RNAs to nascent target transcripts, mediate cotranscriptional silencing of transposons and repetitive genomic loci through heterochromatin formation. The molecular mechanisms involved in this pr
A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing
Autor:
Alexander Zoufaly, Christoph Wenisch, Tamara Seitz, Vienna Covid Diagnostics Initiative, Benedikt Bauer, Johannes Stadlmann, Robert Fritsche-Polanz, Manuela Foedinger, Johannes Zuber, James J. Ross, Marianna Traugott, Andrea Pauli, Jakob Schnabl, Luis Menéndez-Arias, Irina Grishkovskaya, Julius Brennecke, Max J. Kellner, Marcus P. S. Dekens, Robert Heinen
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Global efforts to combat the Covid-19 pandemic caused by the beta coronavirus SARS-CoV-2 are currently based on RT-qPCR-based diagnostic tests. However, their high cost, moderate throughput and reliance on sophisticated equipment limit widespread imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232a376679f8d4f36cfcb0c37d775e74
https://doi.org/10.1101/2020.06.23.166397
https://doi.org/10.1101/2020.06.23.166397
Autor:
Stefan L. Ameres, Fabio Mohn, Jakob Schnabl, Rippei Hayashi, Julius Brennecke, Dominik Handler
Publikováno v:
Nature
Small regulatory RNAs guide Argonaute (Ago) proteins in a sequence-specific manner to their targets and therefore have important roles in eukaryotic gene silencing. Of the three small RNA classes, microRNAs and short interfering RNAs are processed fr
Autor:
Julia Batki, Karl Mechtler, Veselin I. Andreev, Dominik Handler, Maria Novatchkova, Kotryna Kauneckaite, Julius Brennecke, Lisa Lampersberger, Christian E. Stieger, Jakob Schnabl, Dinshaw J. Patel, Juncheng Wang, Wei Xie
Publikováno v:
Nature Structural & Molecular Biology
Nature structural & molecular biology
Nature structural & molecular biology
The PIWI-interacting RNA (piRNA) pathway protects genome integrity in part through establishing repressive heterochromatin at transposon loci. Silencing requires piRNA-guided targeting of nuclear PIWI proteins to nascent transposon transcripts, yet t