Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jakob S. Satz"'
Publikováno v:
Proceedings of the National Academy of Sciences. 111:17570-17575
Misfolded proteins are an emerging hallmark of cardiac diseases. Although some misfolded proteins, such as desmin, are associated with mutations in the genes encoding these disease-associated proteins, little is known regarding more general mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d20e0efb18c250ebf67a0302f2d748
https://doi.org/10.1073/pnas.1420196111
https://doi.org/10.1073/pnas.1420196111
Autor:
Peng Zhang, Huaiyu Hu, Michael Tiemeyer, Kevin P. Campbell, David Live, Mindy Porterfield, Lance Wells, Jakob S. Satz, Sean W. Buskirk, Mian Liu, Kazuhiro Aoki, Yufang Xiong, Jae-Min Lim, Stephanie H. Stalnaker
Publikováno v:
Journal of Biological Chemistry. 286:21180-21190
Dystroglycanopathies are a subset of congenital muscular dystrophies wherein α-dystroglycan (α-DG) is hypoglycosylated. α-DG is an extensively O-glycosylated extracellular matrix-binding protein and a key component of the dystrophin-glycoprotein c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b432dae15e035b96fb899938caa28e5
https://doi.org/10.1074/jbc.m110.203281
https://doi.org/10.1074/jbc.m110.203281
Autor:
Karen Wolburg-Buchholz, Petra Fallier-Becker, Susan Noell, Jakob S. Satz, Kevin P. Campbell, Hartwig Wolburg, Andreas F. Mack, Aaron M. Beedle
Publikováno v:
The European Journal of Neuroscience
The dystrophin–dystroglycan complex (DDC) is a molecular array of proteins in muscle and brain cells. The central component of the DDC is dystroglycan, which comprises α- and β-subunits. α-Dystroglycan (α-DG) binds to extracellular matrix compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d2957cc6aa9a841002599e5bdbf4d9
http://europepmc.org/articles/PMC3342013
http://europepmc.org/articles/PMC3342013
Autor:
Jane C. Lee, Amy Turner, Steven A. Moore, Hajime Kusano, Kevin P. Campbell, Huy A. Nguyen, Toshinori Hoshi, Steve Westra, Susan E. Ross-Barta, Adam P. Ostendorf, Jakob S. Satz, Rolf Turk, Shangwei Hou
Publikováno v:
The Journal of Neuroscience. 30:14560-14572
Cobblestone (type II) lissencephaly and mental retardation are characteristic features of a subset of congenital muscular dystrophies that include Walker–Warburg syndrome, muscle-eye-brain disease, and Fukuyama-type congenital muscular dystrophy. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7e2834e40739dc024ad3e590047692
https://doi.org/10.1523/jneurosci.3247-10.2010
https://doi.org/10.1523/jneurosci.3247-10.2010
Autor:
Takako Sasaki, Daniel E. Michele, Rita Barresi, Jakob S. Satz, Hajime Kusano, Michael D. Henry, Motoi Kanagawa, Rupert Timpl, Kevin P. Campbell
Publikováno v:
FEBS Letters. 579:4792-4796
Dystroglycan is a cell-surface matrix receptor that requires LARGE-dependent glycosylation for laminin binding. Although the interaction of dystroglycan with laminin has been well characterized, less is known about the role of dystroglycan glycosylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358074627d497e903942c6eb61df2318
https://doi.org/10.1016/j.febslet.2005.07.059
https://doi.org/10.1016/j.febslet.2005.07.059
Autor:
Bálint Szabó, Jakob S. Satz, Kevin P. Campbell, Veronika Jancsik, Elod Mehes, Andras Czirok, Tamás Vicsek, Balazs Hegedus
Publikováno v:
Glia. 49:492-500
We investigate the role of dystroglycan, a major laminin-1 receptor and central member of the dystrophin- glycoprotein complex, in the laminin-1 induced mo- tility of cultured Muller glial cells. Binding of laminin-1 to dystroglycan was prevented by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dfd6924f6c5c2cab08604d5ffff92d8
https://doi.org/10.1002/glia.20135
https://doi.org/10.1002/glia.20135
Publikováno v:
The Journal of Cell Biology
In nonneuronal cells, the cell surface protein dystroglycan links the intracellular cytoskeleton (via dystrophin or utrophin) to the extracellular matrix (via laminin, agrin, or perlecan). Impairment of this linkage is instrumental in the pathogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a073d2e7c1932bcc07f0fe17c9c918
http://europepmc.org/articles/PMC2150755
http://europepmc.org/articles/PMC2150755
Autor:
Kevin P. Campbell, Jakob S. Satz
Publikováno v:
Nature Neuroscience. 11:857-859
A new study identifies pikachurin, a previously-unknown dystroglycan-binding protein that is critical for the apposition of photoreceptor and bipolar cell dendrites at the ribbon synapse. This work could explain some of the visual defects seen in sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a98de9cb4810cab785529e28413bfd81
https://doi.org/10.1038/nn0808-857
https://doi.org/10.1038/nn0808-857
Autor:
Ray A. M. Daza, Jakob S. Satz, Timothy D. Myshrall, Robert F. Hevner, Adam P. Ostendorf, Tom Kowalczyk, Charmaine Lau, Kevin P. Campbell, Huy Nguyen, Steven A. Moore
Interactions between the embryonic pial basement membrane (PBM) and radial glia (RG) are essential for morphogenesis of the cerebral cortex, as disrupted interactions cause cobblestone malformations. To elucidate the role of dystroglycan (DG) in PBM-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f028ab3624c91f0c314fa8a615cfc7b4
https://europepmc.org/articles/PMC3512206/
https://europepmc.org/articles/PMC3512206/
Autor:
Steven J. Burden, Michael B. A. Oldstone, Zihan Zhu, Yuji Hara, Yvonne M. Kobayashi, Motoi Kanagawa, Takako Yoshida-Moriguchi, Jakob S. Satz, Stefan Kunz, Kevin P. Campbell
α-dystroglycan is a highly O -glycosylated extracellular matrix receptor that is required for anchoring of the basement membrane to the cell surface and for the entry of Old World arenaviruses into cells. Like-acetylglucosaminyltransferase (LARGE) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e0ce7f5b777e1e578320b7f5f82996
https://europepmc.org/articles/PMC3198351/
https://europepmc.org/articles/PMC3198351/