Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jakob S. Hansen"'
Autor:
Peter Plomgaard, Jakob S. Hansen, Logan K. Townsend, Anders Gudiksen, Niels H. Secher, Jens O. Clemmesen, Rene K. Støving, Jens P. Goetze, David C. Wright, Henriette Pilegaard
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveGrowth differentiation factor (GDF)-15 is implicated in regulation of metabolism and circulating GDF15 increases in response to exercise. The source and regulation of the exercise-induced increase in GDF15 is, however not known.MethodPlasma
Externí odkaz:
https://doaj.org/article/ce58d911641d489ab432f2d4f5be64b9
Autor:
Bodil Ingerslev, Jakob S. Hansen, Christoph Hoffmann, Jens O. Clemmesen, Niels H. Secher, Mika Scheler, Martin Hrabĕ de Angelis, Hans U. Häring, Bente K. Pedersen, Cora Weigert, Peter Plomgaard
Publikováno v:
Molecular Metabolism, Vol 6, Iss 10, Pp 1286-1295 (2017)
Objective: Angiopoietin-like protein-4 (ANGPTL4) is a circulating protein that is highly expressed in liver and implicated in regulation of plasma triglyceride levels. Systemic ANGPTL4 increases during prolonged fasting and is suggested to be secrete
Externí odkaz:
https://doaj.org/article/09fa3316dd9b4a0182e32ce423ccbb02
Autor:
Nora E. Zois, Dijana Terzic, Kristine Færch, Peter Plomgaard, Jakob S. Hansen, Peter Rossing, Jens P. Goetze
Publikováno v:
EBioMedicine, Vol 17, Iss C, Pp 88-94 (2017)
Plasma concentrations of pro-Atrial natriuretic peptide, proANP, are decreased in obesity and diabetes. Decreased proANP concentrations have also been noted after meal intake, and recently, a glucose-mediated regulation of ANP gene expression was rep
Externí odkaz:
https://doaj.org/article/9e853a3aad2c4380b970599e645688b0
Autor:
Margrethe Kjeldsen, Jakob S. Hansen, Maria Veiga-da-Cunha, Antonia Ribes, Rikke Katrine Jentoft Olsen, Sarah Fogh, Anne Bie, Lars Aagaard, Niels Gregersen, Emile Van Schaftingen, Graziana Dipace, Signe Mosegaard
Publikováno v:
Journal of Inherited Metabolic Disease
Journal of inherited metabolic disease, Vol. 44, no. 5, p. 1215-1225 (2021)
Fogh, S, Dipace, G, Bie, A, Veiga-da-Cunha, M, Hansen, J, Kjeldsen, M, Mosegaard, S, Ribes, A, Gregersen, N, Aagaard, L, Schaftingen, E V & Olsen, R K J 2021, ' Variants in the Ethylmalonyl-CoA Decarboxylase (ECHDC1) Gene; a Novel Player in Ethylmalonic Aciduria? ', Journal of Inherited Metabolic Disease, vol. 44, no. 5, pp. 1215-1225 . https://doi.org/10.1002/jimd.12394
Journal of inherited metabolic disease, Vol. 44, no. 5, p. 1215-1225 (2021)
Fogh, S, Dipace, G, Bie, A, Veiga-da-Cunha, M, Hansen, J, Kjeldsen, M, Mosegaard, S, Ribes, A, Gregersen, N, Aagaard, L, Schaftingen, E V & Olsen, R K J 2021, ' Variants in the Ethylmalonyl-CoA Decarboxylase (ECHDC1) Gene; a Novel Player in Ethylmalonic Aciduria? ', Journal of Inherited Metabolic Disease, vol. 44, no. 5, pp. 1215-1225 . https://doi.org/10.1002/jimd.12394
Ethylmalonic acid (EMA) is a major and potentially cytotoxic metabolite associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency, a condition whose status as a disease is uncertain. Unexplained high EMA is observed in some individuals wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0ca0f4372aa4899835ee760290b049
https://pubmed.ncbi.nlm.nih.gov/33973257
https://pubmed.ncbi.nlm.nih.gov/33973257
Autor:
Jonas Agerlund Povlsen, Marie Vognstoft Hjortbak, Hans Erik Bøtker, Rebekka Vibjerg Jensen, Derek J. Hausenloy, Jakob S. Hansen, Thomas Ravn Lassen, Johanne Hjort, Nicolaj B. Støttrup, Nichlas Riise Jespersen
Publikováno v:
Scientific Reports
Hjortbak, M V, Jespersen, N R, Jensen, R V, Lassen, T R, Hjort, J, Povlsen, J A, Støttrup, N B, Hansen, J, Hausenloy, D J & Bøtker, H E 2021, ' Cardioprotective effect of combination therapy by mild hypothermia and local or remote ischemic preconditioning in isolated rat hearts ', Scientific Reports, vol. 11, no. 1, 265 . https://doi.org/10.1038/s41598-020-79449-x
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Hjortbak, M V, Jespersen, N R, Jensen, R V, Lassen, T R, Hjort, J, Povlsen, J A, Støttrup, N B, Hansen, J, Hausenloy, D J & Bøtker, H E 2021, ' Cardioprotective effect of combination therapy by mild hypothermia and local or remote ischemic preconditioning in isolated rat hearts ', Scientific Reports, vol. 11, no. 1, 265 . https://doi.org/10.1038/s41598-020-79449-x
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
A multitargeted strategy to treat the consequences of ischemia and reperfusion (IR) injury in acute myocardial infarction may add cardioprotection beyond reperfusion therapy alone. We investigated the cardioprotective effect of mild hypothermia combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515d3caf312a5d7641ab74f90052d7da
https://pubmed.ncbi.nlm.nih.gov/33431942
https://pubmed.ncbi.nlm.nih.gov/33431942
Autor:
Rainer Lehmann, Benedikt Karus, Miriam Hoene, Cora Weigert, Peter Plomgaard, Hans U. Häring, Xinjie Zhao, Guowang Xu, Sean H. Adams, Andreas M. Niess, Hany F. Sobhi, Jakob S. Hansen
Publikováno v:
Sobhi, H F, Zhao, X, Plomgaard, P, Hoene, M, Hansen, J S, Karus, B, Niess, A M, Häring, H U, Lehmann, R, Adams, S H, Xu, G & Weigert, C 2020, ' Identification and regulation of the xenometabolite derivatives cis-and trans-3,4-methylene-heptanoylcarnitine in plasma and skeletal muscle of exercising humans ', American Journal of Physiology: Endocrinology and Metabolism, vol. 318, no. 5, pp. E701-E709 . https://doi.org/10.1152/ajpendo.00510.2019
Am. J. Physiol. Endocrinol. Metab. 318, E701-E709 (2020)
Am. J. Physiol. Endocrinol. Metab. 318, E701-E709 (2020)
Little is known about xenometabolites in human metabolism, particularly under exercising conditions. Previously, an exercise-modifiable, likely xenometabolite derivative, cis-3,4-methylene-heptanoylcarnitine, was reported in human plasma. Here, we id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2440796c6dd183039b57a450f5295d0
https://curis.ku.dk/portal/da/publications/identification-and-regulation-of-the-xenometabolite-derivatives-cis-and-trans34methyleneheptanoylcarnitine-in-plasma-and-skeletal-muscle-of-exercising-humans(a68fe202-8ff6-4de7-8ba4-4df1be38d317).html
https://curis.ku.dk/portal/da/publications/identification-and-regulation-of-the-xenometabolite-derivatives-cis-and-trans34methyleneheptanoylcarnitine-in-plasma-and-skeletal-muscle-of-exercising-humans(a68fe202-8ff6-4de7-8ba4-4df1be38d317).html
Autor:
Jakob S. Hansen, Miriam Hoene, Xiaolin Wang, Chunxiu Hu, Jens Otto Clemmesen, Hans U. Häring, Peter Plomgaard, Rainer Lehmann, Cora Weigert, Jia Li, Guowang Xu, Niels H. Secher, Xinjie Zhao
Publikováno v:
Hu, C, Hoene, M, Plomgaard, P, Hansen, J S, Zhao, X, Li, J, Wang, X, Clemmesen, J O, Secher, N H, Häring, H U, Lehmann, R, Xu, G & Weigert, C 2020, ' Muscle-Liver Substrate Fluxes in Exercising Humans and Potential Effects on Hepatic Metabolism ', The Journal of clinical endocrinology and metabolism, vol. 105, no. 4, pp. 1196-1209 . https://doi.org/10.1210/clinem/dgz266
The Journal of Clinical Endocrinology and Metabolism
J. Clin. Endocrinol. Metab. 105, 1196–1209 (2020)
The Journal of Clinical Endocrinology and Metabolism
J. Clin. Endocrinol. Metab. 105, 1196–1209 (2020)
Context The liver is crucial to maintain energy homeostasis during exercise. Skeletal muscle-derived metabolites can contribute to the regulation of hepatic metabolism. Objective We aim to elucidate which metabolites are released from the working mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d7ff5117eb290503dcae08957c6870
https://curis.ku.dk/ws/files/243062821/Muscle_Liver_Substrate_Fluxes_in_Exercising_Humans_and_Potential_Effects_on_Hepatic_Metabolism.pdf
https://curis.ku.dk/ws/files/243062821/Muscle_Liver_Substrate_Fluxes_in_Exercising_Humans_and_Potential_Effects_on_Hepatic_Metabolism.pdf
Autor:
Hany F, Sobhi, Xinjie, Zhao, Peter, Plomgaard, Miriam, Hoene, Jakob S, Hansen, Benedikt, Karus, Andreas M, Niess, Hans U, Häring, Rainer, Lehmann, Sean H, Adams, Guowang, Xu, Cora, Weigert
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 318(5)
Little is known about xenometabolites in human metabolism, particularly under exercising conditions. Previously, an exercise-modifiable, likely xenometabolite derivative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c260c5b01b6925329ad404074e577786
https://pubmed.ncbi.nlm.nih.gov/32101032
https://pubmed.ncbi.nlm.nih.gov/32101032
Autor:
Jakob S. Hansen, Michel Pinget, Bente Klarlund Pedersen, Cédric Howald, Peter Plomgaard, Emmanouil T. Dermitzakis, Sabine Rütti, Karim Bouzakri, Rodolphe Dusaulcy
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Rutti, S, Dusaulcy, R, Hansen, J S, Howald, C, Dermitzakis, E T, Pedersen, B K, Pinget, M, Plomgaard, P & Bouzakri, K 2018, ' Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines ', Scientific Reports, vol. 8, 10072 . https://doi.org/10.1038/s41598-018-28117-2
Scientific Reports
Scientific Reports, Vol. 8, No 1 (2018) P. 10072
Rutti, S, Dusaulcy, R, Hansen, J S, Howald, C, Dermitzakis, E T, Pedersen, B K, Pinget, M, Plomgaard, P & Bouzakri, K 2018, ' Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines ', Scientific Reports, vol. 8, 10072 . https://doi.org/10.1038/s41598-018-28117-2
Scientific Reports
Scientific Reports, Vol. 8, No 1 (2018) P. 10072
Tissue cross-talk is emerging as a determinant way to coordinate the different organs implicated in glucose homeostasis. Among the inter-organ communication factors, muscle-secreted myokines can modulate the function and survival of pancreatic beta-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7eb3776ec1a6ed76a6813582cbcd197
http://link.springer.com/article/10.1038/s41598-018-28117-2
http://link.springer.com/article/10.1038/s41598-018-28117-2
Autor:
Bente Klarlund Pedersen, Jens Otto Clemmesen, Martin Hrabĕ de Angelis, Hans U. Häring, C Hoffmann, Peter Plomgaard, Cora Weigert, Niels H. Secher, Jakob S. Hansen, Mika Scheler, Bodil Ingerslev
Publikováno v:
Molecular Metabolism
Ingerslev, B, Hansen, J S, Hoffmann, C, Clemmesen, J O, Secher, N H, Scheler, M, Hrabĕ de Angelis, M, Häring, H U, Pedersen, B K, Weigert, C & Plomgaard, P 2017, ' Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP ', Molecular Metabolism, vol. 6, no. 10, pp. 1286-1295 . https://doi.org/10.1016/j.molmet.2017.06.018
Mol. Metab. 6, 1286-1295 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1286-1295 (2017)
Ingerslev, B, Hansen, J S, Hoffmann, C, Clemmesen, J O, Secher, N H, Scheler, M, Hrabĕ de Angelis, M, Häring, H U, Pedersen, B K, Weigert, C & Plomgaard, P 2017, ' Angiopoietin-like protein 4 is an exercise-induced hepatokine in humans, regulated by glucagon and cAMP ', Molecular Metabolism, vol. 6, no. 10, pp. 1286-1295 . https://doi.org/10.1016/j.molmet.2017.06.018
Mol. Metab. 6, 1286-1295 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1286-1295 (2017)
Objective Angiopoietin-like protein-4 (ANGPTL4) is a circulating protein that is highly expressed in liver and implicated in regulation of plasma triglyceride levels. Systemic ANGPTL4 increases during prolonged fasting and is suggested to be secreted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d73cb2ab1ae1c0951dd42251e141dc9
http://europepmc.org/articles/PMC5641605
http://europepmc.org/articles/PMC5641605