Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jakob M Townsend"'
Publikováno v:
Tissue Engineering Part C: Methods. 28:137-147
Manual tissue decellularization is an onerous process that requires the application of many sequential treatments by an operator and can be prone to user error and result variability. While automated decellularization devices have been previously rep
Publikováno v:
Journal of Biomechanics. 152:111592
Publikováno v:
Biomaterials Science. 9:2339-2361
Tissue repair requires a complex cascade of events mediated by a variety of cells, proteins, and matrix molecules; however, the healing cascade can be easily disrupted by numerous factors, resulting in impaired tissue regeneration. Recent advances in
Publikováno v:
Biomedical materials (Bristol, England). 17(6)
Hyaluronic acid (HA) hydrogels have been used for a multitude of applications, perhaps most notably for tissue engineering and regenerative medicine, owing to the versatility of the polymer and its tunable nature. Various groups have investigated the
Publikováno v:
Tissue Eng Part C Methods
Tracheal tissue engineering has become an active area of interest among clinical and scientific communities; however, methods to evaluate success of in vivo tissue-engineered solutions remain primarily qualitative. These evaluation methods have gener
Autor:
Cory Berkland, Scott Barbay, Jakob M. Townsend, Sheila Tsau, Brian T. Andrews, Randolph J. Nudo, Michael S. Detamore, Chad A. Tuchek
Publikováno v:
Journal of Craniofacial Surgery. 31:2364-2367
Background Syndrome of the trephined is a neurologic condition that commonly arises in patients who undergo craniectomy and have a prolonged cranial defect. Symptoms of this condition include headache, difficulties concentrating, diminished fine moto
Autor:
Bradley N. Bohnstedt, Michael S. Detamore, Hannah B. Homburg, Randolph J. Nudo, Goksel Sali, Megan E. Sanders, Kar Ming Fung, Jakob M. Townsend, Brian T. Andrews, Nina T. Cassidy
Publikováno v:
Acta Biomaterialia. 104:66-75
Bone regeneration of large cranial defects, potentially including traumatic brain injury (TBI) treatment, presents a major problem with non-crosslinking, clinically available products due to material migration outside the defect. Commercial products
Publikováno v:
Annals of Biomedical Engineering. 47:2308-2321
A synthetic ‘chondroinductive’ biomaterial that could induce chondrogenesis without the need for growth factors, extracellular matrix, or pre-seeded cells could revolutionize orthopedic regenerative medicine. The objective of the current study wa
Publikováno v:
Progress in Polymer Science. 91:126-140
Hydrogels – water swollen cross-linked networks – have demonstrated considerable promise in tissue engineering and regenerative medicine applications. However, ambiguity over which rheological properties are needed to characterize these gels befo
Unrepaired decompressive craniectomy worsens motor performance in a rat traumatic brain injury model
Autor:
Brian T. Andrews, Scott Barbay, Jakob M. Townsend, Chad A. Tuchek, Janna L. Harris, Randolph J. Nudo, Michael S. Detamore
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Decompressive craniectomy (DC) is often required to manage rising intracranial pressure after traumatic brain injury (TBI). Syndrome of the trephine (SoT) is a reversible neurologic condition that often occurs following DC as a result of the unrepair