Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jakob Lovén"'
Autor:
Diogo Ribeiro, Marcus D.R. Klarqvist, Ulrica K. Westermark, Ganna Oliynyk, Johanna Dzieran, Anna Kock, Carolina Savatier Banares, Falk Hertwig, John Inge Johnsen, Matthias Fischer, Per Kogner, Jakob Lovén, Marie Arsenian Henriksson
Publikováno v:
Cell Reports, Vol 16, Iss 4, Pp 979-993 (2016)
MYCN amplification and MYC signaling are associated with high-risk neuroblastoma with poor prognosis. Treating these tumors remains challenging, although therapeutic approaches stimulating differentiation have generated considerable interest. We have
Externí odkaz:
https://doaj.org/article/9441ad4f0eaa42cfb9e4ee5158ce8eea
Autor:
Ravindra Majeti, Christian C. Fritz, Jakob Lovén, David A. Orlando, Matthew G. Guenther, Kathryn Austgen, Julie L. Koenig, Steven M. Chan, Darren Smith, Mei Wei Chen, Jeremy T. Lopez, Emily Lee, Chris Fiore, Matthew L. Eaton, M. Ryan Corces, Michael R. McKeown
Supplementary and expanded descriptions of methods and figure legends for supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ce0731c1ab271f56fe50dc912ba80a
https://doi.org/10.1158/2159-8290.22531178.v1
https://doi.org/10.1158/2159-8290.22531178.v1
Autor:
Ravindra Majeti, Christian C. Fritz, Jakob Lovén, David A. Orlando, Matthew G. Guenther, Kathryn Austgen, Julie L. Koenig, Steven M. Chan, Darren Smith, Mei Wei Chen, Jeremy T. Lopez, Emily Lee, Chris Fiore, Matthew L. Eaton, M. Ryan Corces, Michael R. McKeown
Supplementary Figure S1. Identification and refinement of cancer-specific super-enhancers in human AML. Supplementary Figure S2. Mapping of super-enhancers to genes. Supplementary Figure S3. AML SE profiles show pronounced variation in enhancers rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42fd9d6b3a394310811a707e168693db
https://doi.org/10.1158/2159-8290.22531181.v1
https://doi.org/10.1158/2159-8290.22531181.v1
Autor:
Ravindra Majeti, Christian C. Fritz, Jakob Lovén, David A. Orlando, Matthew G. Guenther, Kathryn Austgen, Julie L. Koenig, Steven M. Chan, Darren Smith, Mei Wei Chen, Jeremy T. Lopez, Emily Lee, Chris Fiore, Matthew L. Eaton, M. Ryan Corces, Michael R. McKeown
GSEA of transcriptional response to SY-1425 in RARA-high cell lines in perturbation gene sets & GSEA of transcriptional response to SY-1425 in RARA-high cell lines in hallmark/pathways and perturbation gene sets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb4020045a987e7437d5c0de65d0244
https://doi.org/10.1158/2159-8290.22531160
https://doi.org/10.1158/2159-8290.22531160
Autor:
Ravindra Majeti, Christian C. Fritz, Jakob Lovén, David A. Orlando, Matthew G. Guenther, Kathryn Austgen, Julie L. Koenig, Steven M. Chan, Darren Smith, Mei Wei Chen, Jeremy T. Lopez, Emily Lee, Chris Fiore, Matthew L. Eaton, M. Ryan Corces, Michael R. McKeown
RNA-seq derived signatures and per-cluster weights for TCGA clustering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9815fa8badd26b64fa3dd9d67cc2bd22
https://doi.org/10.1158/2159-8290.22531172.v1
https://doi.org/10.1158/2159-8290.22531172.v1
Autor:
Ravindra Majeti, Christian C. Fritz, Jakob Lovén, David A. Orlando, Matthew G. Guenther, Kathryn Austgen, Julie L. Koenig, Steven M. Chan, Darren Smith, Mei Wei Chen, Jeremy T. Lopez, Emily Lee, Chris Fiore, Matthew L. Eaton, M. Ryan Corces, Michael R. McKeown
Table of median survival in TCGA data by predicted clusters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f2178f7c8cfce13a29a97f4969a997
https://doi.org/10.1158/2159-8290.22531166.v1
https://doi.org/10.1158/2159-8290.22531166.v1
Autor:
Ravindra Majeti, Christian C. Fritz, Jakob Lovén, David A. Orlando, Matthew G. Guenther, Kathryn Austgen, Julie L. Koenig, Steven M. Chan, Darren Smith, Mei Wei Chen, Jeremy T. Lopez, Emily Lee, Chris Fiore, Matthew L. Eaton, M. Ryan Corces, Michael R. McKeown
GREAT analysis of genes near H3K27ac peaks up-regulated by SY-1425 in RARA-high cell lines in perturbation gene sets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfd72dc3781eb926cf474e51a9e2ae0
https://doi.org/10.1158/2159-8290.22531157.v1
https://doi.org/10.1158/2159-8290.22531157.v1
Autor:
Ravindra Majeti, Christian C. Fritz, Jakob Lovén, David A. Orlando, Matthew G. Guenther, Kathryn Austgen, Julie L. Koenig, Steven M. Chan, Darren Smith, Mei Wei Chen, Jeremy T. Lopez, Emily Lee, Chris Fiore, Matthew L. Eaton, M. Ryan Corces, Michael R. McKeown
Patient sample features including cytogenetic alterations and mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e81b14e8811035b0a4fcee3b056562
https://doi.org/10.1158/2159-8290.22531175.v1
https://doi.org/10.1158/2159-8290.22531175.v1
Autor:
Ravindra Majeti, Christian C. Fritz, Jakob Lovén, David A. Orlando, Matthew G. Guenther, Kathryn Austgen, Julie L. Koenig, Steven M. Chan, Darren Smith, Mei Wei Chen, Jeremy T. Lopez, Emily Lee, Chris Fiore, Matthew L. Eaton, M. Ryan Corces, Michael R. McKeown
Table of Enhancer, mRNA, and SY-1425 EC50 values in AML cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b32533f8fee6ab3c9dff0db2a0307a
https://doi.org/10.1158/2159-8290.22531163.v1
https://doi.org/10.1158/2159-8290.22531163.v1
Autor:
Ravindra Majeti, Darren Smith, Mei Wei Chen, Matthew L. Eaton, Steven M. Chan, Emily Payton Lee, Jeremy Lopez, Christian C. Fritz, Chris Fiore, Kathryn Austgen, Jakob Lovén, M. Ryan Corces, Matthew G. Guenther, Michael R. Mckeown, Julie L. Koenig, David A. Orlando
Publikováno v:
Cancer Discovery. 7:1136-1153
We characterized the enhancer landscape of 66 patients with acute myeloid leukemia (AML), identifying 6 novel subgroups and their associated regulatory loci. These subgroups are defined by their superenhancer (SE) maps, orthogonal to somatic mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4083ff05e6222cbcf0c27653ced35b16
https://doi.org/10.1158/2159-8290.cd-17-0399
https://doi.org/10.1158/2159-8290.cd-17-0399