Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jakob Karen"'
Autor:
Nusayba Bagegni, Shana Thomas, Ning Liu, Jingqin Luo, Jeremy Hoog, Donald W. Northfelt, Matthew P. Goetz, Andres Forero, Mattias Bergqvist, Jakob Karen, Magnus Neumüller, Edward M. Suh, Zhanfang Guo, Kiran Vij, Souzan Sanati, Matthew Ellis, Cynthia X. Ma
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Thymidine kinase 1 (TK1) is a cell cycle-regulated enzyme with peak expression in the S phase during DNA synthesis, and it is an attractive biomarker of cell proliferation. Serum TK1 activity has demonstrated prognostic value in p
Externí odkaz:
https://doaj.org/article/e2effa9a641b4f7696e08654cd042fb5
Autor:
Jeremy Hoog, Ning Liu, Andres Forero, Cynthia X. Ma, Matthias Bergqvist, Donald W. Northfelt, Shana Thomas, Souzan Sanati, Matthew J. Ellis, Edward M Suh, Magnus Neumuller, Kiran Vij, Jingqin Luo, Nusayba Bagegni, Matthew P. Goetz, Zhanfang Guo, Jakob Karen
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 19, Iss 1, Pp 1-11 (2017)
Breast Cancer Research, Vol 19, Iss 1, Pp 1-11 (2017)
Background Thymidine kinase 1 (TK1) is a cell cycle-regulated enzyme with peak expression in the S phase during DNA synthesis, and it is an attractive biomarker of cell proliferation. Serum TK1 activity has demonstrated prognostic value in patients w
Publikováno v:
Cancer Research. 77:4024-4024
Targeted therapies are dependent on adequate occupancy and target engagement to reach their efficacy measure. Yet, more than half of novel candidate drugs entering clinical trial stage fail before proof of concept is achieved. Inadequate target engag
Publikováno v:
Cancer Research. 76:354-354
Targeted therapies are dependent on adequate occupancy and target engagement to reach their efficacy measure. Yet, more than half of novel candidate drugs entering clinical trial stage fail before proof of concept is achieved. Inadequate target engag
Autor:
Jakob Karén, Alejandro Rodriguez, Tomas Friman, Lennart Dencker, Christian Sundberg, Birger Scholz
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24954 (2011)
Microvascular pericytes are of key importance in neoformation of blood vessels, in stabilization of newly formed vessels as well as maintenance of angiostasis in resting tissues. Furthermore, pericytes are capable of differentiating into pro-fibrotic
Externí odkaz:
https://doaj.org/article/8077904b187547388e02e5df0ee2a833