Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jakob Einhaus"'
Autor:
Jakob Einhaus, Dyani K. Gaudilliere, Julien Hedou, Dorien Feyaerts, Michael G. Ozawa, Masaki Sato, Edward A. Ganio, Amy S. Tsai, Ina A. Stelzer, Karl C. Bruckman, Jonas N. Amar, Maximilian Sabayev, Thomas A. Bonham, Joshua Gillard, Maïgane Diop, Amelie Cambriel, Zala N. Mihalic, Tulio Valdez, Stanley Y. Liu, Leticia Feirrera, David K. Lam, John B. Sunwoo, Christian M. Schürch, Brice Gaudilliere, Xiaoyuan Han
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108486- (2023)
Summary: Oral squamous cell carcinoma (OSCC), a prevalent and aggressive neoplasm, poses a significant challenge due to poor prognosis and limited prognostic biomarkers. Leveraging highly multiplexed imaging mass cytometry, we investigated the tumor
Externí odkaz:
https://doaj.org/article/869544f8ba5e4b78a97cd60fb2d44b05
Autor:
Natalie Stanley, Ina A. Stelzer, Amy S. Tsai, Ramin Fallahzadeh, Edward Ganio, Martin Becker, Thanaphong Phongpreecha, Huda Nassar, Sajjad Ghaemi, Ivana Maric, Anthony Culos, Alan L. Chang, Maria Xenochristou, Xiaoyuan Han, Camilo Espinosa, Kristen Rumer, Laura Peterson, Franck Verdonk, Dyani Gaudilliere, Eileen Tsai, Dorien Feyaerts, Jakob Einhaus, Kazuo Ando, Ronald J. Wong, Gerlinde Obermoser, Gary M. Shaw, David K. Stevenson, Martin S. Angst, Brice Gaudilliere, Nima Aghaeepour
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Single-cell technologies are increasingly prominent in clinical applications, but predictive modelling with such data in large cohorts has remained computationally challenging. We developed a new algorithm, ‘VoPo’, for predictive modelling and vi
Externí odkaz:
https://doaj.org/article/e63eb4be164c423694059f87cd18e59d
Autor:
Edward A. Ganio, Natalie Stanley, Viktoria Lindberg-Larsen, Jakob Einhaus, Amy S. Tsai, Franck Verdonk, Anthony Culos, Sajjad Ghaemi, Kristen K. Rumer, Ina A. Stelzer, Dyani Gaudilliere, Eileen Tsai, Ramin Fallahzadeh, Benjamin Choisy, Henrik Kehlet, Nima Aghaeepour, Martin S. Angst, Brice Gaudilliere
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Glucocorticoids (GC) are commonly used to suppress undesirable inflammatory responses. Here the authors show, using hi-dimensional flow cytometry data, that GC treatment following major surgeries alters adaptive immunity without significant modulatio
Externí odkaz:
https://doaj.org/article/3016b93a2903454094208dd5c4152489
Autor:
Jakob Einhaus, Ann-Christin Pecher, Elisa Asteriti, Hannes Schmid, Kathy-Ann Secker, Silke Duerr-Stoerzer, Hildegard Keppeler, Reinhild Klein, Corina Schneidawind, Joerg Henes, Dominik Schneidawind
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-8 (2020)
Abstract Objective Systemic sclerosis (SSc) is a connective tissue disease with a significant morbidity and reduced survival of patients. Effective treatment and clinical control of the disease remain challenging. In particular, the development of pu
Externí odkaz:
https://doaj.org/article/27b4f8019cdc4954ac224882d2b9813f
Autor:
Simona Jahnke, Hannes Schmid, Kathy-Ann Secker, Jakob Einhaus, Silke Duerr-Stoerzer, Hildegard Keppeler, Irmtraud Schober-Melms, Rebecca Baur, Michael Schumm, Rupert Handgretinger, Wolfgang Bethge, Lothar Kanz, Corina Schneidawind, Dominik Schneidawind
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Allogeneic hematopoietic cell transplantation (allo-HCT) is a curative treatment option for hematologic malignancies but relapse remains the most common cause of death. Infusion of donor lymphocytes (DLIs) can induce remission and prolong survival by
Externí odkaz:
https://doaj.org/article/408572c894f945a9803769e6512d431b
Autor:
Xiaoyuan Han, Mohammad S. Ghaemi, Kazuo Ando, Laura S. Peterson, Edward A. Ganio, Amy S. Tsai, Dyani K. Gaudilliere, Ina A. Stelzer, Jakob Einhaus, Basile Bertrand, Natalie Stanley, Anthony Culos, Athena Tanada, Julien Hedou, Eileen S. Tsai, Ramin Fallahzadeh, Ronald J. Wong, Amy E. Judy, Virginia D. Winn, Maurice L. Druzin, Yair J. Blumenfeld, Mark A. Hlatky, Cecele C. Quaintance, Ronald S. Gibbs, Brendan Carvalho, Gary M. Shaw, David K. Stevenson, Martin S. Angst, Nima Aghaeepour, Brice Gaudilliere
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Preeclampsia is one of the most severe pregnancy complications and a leading cause of maternal death. However, early diagnosis of preeclampsia remains a clinical challenge. Alterations in the normal immune adaptations necessary for the maintenance of
Externí odkaz:
https://doaj.org/article/d6c4dbcad99b424ba7d6e1e76d63d1d3
Autor:
Edward A. Ganio, Natalie Stanley, Viktoria Lindberg-Larsen, Jakob Einhaus, Amy S. Tsai, Franck Verdonk, Anthony Culos, Sajjad Ghaemi, Kristen K. Rumer, Ina A. Stelzer, Dyani Gaudilliere, Eileen Tsai, Ramin Fallahzadeh, Benjamin Choisy, Henrik Kehlet, Nima Aghaeepour, Martin S. Angst, Brice Gaudilliere
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/9ac3d601e43f4c649e7825841f1871f9
Publikováno v:
Virchows Archiv. 482:801-812
High-multiplex tissue imaging (HMTI) approaches comprise several novel immunohistological methods that enable in-depth, spatial single-cell analysis. Over recent years, studies in tumor biology, infectious diseases, and autoimmune conditions have dem
Autor:
Jakob Einhaus, Elisa Asteriti, Ann-Christin Pecher, Hildegard Keppeler, Reinhild Klein, Corina Schneidawind, Joerg Henes, Dominik Schneidawind
Publikováno v:
Cytotherapy. 24:482-488
Systemic sclerosis (SSc) is a connective tissue disease with poorly understood pathogenesis and limited treatment options. Patient mortality is rooted predominantly in the development of pulmonary and cardiac complications. The overactivated immune s
Autor:
Julien Hedou, Ivana Maric, Grégoire Bellan, Jakob Einhaus, Dyani Gaudilliere, Francois-Xavier Ladant, Franck Verdonk, Ina Stelzer, Dorien Feyaerts, Amy Tsai, Edward Ganio, Maximilian Sabayev, Joshua Gillard, Adam Bonham, Masaki Sato, Maïgane Diop, Martin Angst, David Stevenson, Nima Aghaeepour, Andrea Montanari, Brice Gaudilliere
High-content omic technologies coupled with sparsity-promoting regularization methods (SRM) have transformed the biomarker discovery process. However, the translation of computational results into a clinical use-case scenario remains challenging. A r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1997f63f2cba9afde03015a85f40f376
https://doi.org/10.21203/rs.3.rs-2609859/v1
https://doi.org/10.21203/rs.3.rs-2609859/v1