Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jakob D Wikstrom"'
Autor:
Matthew Hunt, Nuoqi Wang, Naricha Pupinyo, Philip Curman, Monica Torres, William Jebril, Maria Chatzinikolaou, Julie Lorent, Gilad Silberberg, Ritu Bansal, Teresa Burner, Jing Zhou, Susanne Kimeswenger, Wolfram Hoetzenecker, Keith Choate, Etty Bachar-Wikstrom, Jakob D Wikstrom
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 1986-2001 (2024)
Abstract Darier disease (DD) is a rare severe acantholytic skin disease caused by mutations in the ATP2A2 gene that encodes for the sarco/endoplasmic reticulum calcium ATPase isoform 2 (SERCA2). SERCA2 maintains endoplasmic reticulum calcium homeosta
Externí odkaz:
https://doaj.org/article/b20f15a21d914c2e8a2d537249034dd9
Autor:
William Jebril, Philip Curman, Daniel C Andersson, Henrik Larsson, Etty Bachar-Wikstrom, Martin Cederlöf, Jakob D Wikstrom
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0309482 (2024)
BackgroundHailey-Hailey disease (HHD) is a rare autosomal dominant skin disease caused by mutations in the ATP2C1 gene, which encodes the secretory Ca2+/Mn2+-ATPase (SPCA1) pump in the Golgi apparatus. Although ATP2C1 is ubiquitously expressed in the
Externí odkaz:
https://doaj.org/article/05b368a0052441d4914494d49edfff35
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0246145 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0205517.].
Externí odkaz:
https://doaj.org/article/709afd850ed0445ea3d1ff348d85dd38
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205517 (2018)
Although clinical guidelines exist, the management of patients with cutaneous melanoma (CM) is a complex process that may vary between different care providers with potential dysfunctions ultimately mirrored in the overall patient satisfaction. The a
Externí odkaz:
https://doaj.org/article/d5be55fc379e4de5b704b3ce5d126c30
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186356 (2017)
Darier disease is a rare and severe autosomal dominant skin disease characterised by malodorous keratotic papules in seborrheic areas of the skin. Darier disease affects up to 1 in 30 000 people and is caused by mutations in the ATP2A2 gene, which en
Externí odkaz:
https://doaj.org/article/1085eb6275b74caebce6324abe20f569
Autor:
Philip Curman, William Jebril, Henrik Larsson, Etty Bachar-Wikstrom, Martin Cederlöf, Jakob D. Wikstrom
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-4 (2024)
Abstract Darier disease (DD) is a rare monogenetic skin disorder with limited data on its potential association with neurological disorders. This study aimed to investigate the association between DD and neurological disorders, specifically Parkinson
Externí odkaz:
https://doaj.org/article/48f2e8b8b0ef488e9190c8d554aee31f
Autor:
Jakob D Wikstrom, Samuel B Sereda, Linsey Stiles, Alvaro Elorza, Emma M Allister, Andy Neilson, David A Ferrick, Michael B Wheeler, Orian S Shirihai
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e33023 (2012)
The pancreatic beta cell is unique in its response to nutrient by increased fuel oxidation. Recent studies have demonstrated that oxygen consumption rate (OCR) may be a valuable predictor of islet quality and long term nutrient responsiveness. To dat
Externí odkaz:
https://doaj.org/article/113026f2fefc41b1898270645fef0a88
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26883 (2011)
Congenital deficiency of the mitochondrial respiratory chain complex I (CI) is a common defect of oxidative phosphorylation (OXPHOS). Despite major advances in the biochemical and molecular diagnostics and the deciphering of CI structure, function as
Externí odkaz:
https://doaj.org/article/92870a0704e54ca39b3e5e3bd05e6598
Autor:
Etty Bachar-Wikstrom, Braham Dhillon, Navi Gill Dhillon, Lisa Abbo, Sara K. Lindén, Jakob D. Wikstrom
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16954 (2023)
The mucus layer covering the skin of fish has several roles, including protection against pathogens and mechanical damage in which proteins play a key role. While proteins in the skin mucus layer of various common bony fish species have been explored
Externí odkaz:
https://doaj.org/article/1c81c13d91b04b35a2fdaed7245ddb28
Autor:
Etty Bachar-Wikstrom, Kristina A. Thomsson, Carina Sihlbom, Lisa Abbo, Haitham Tartor, Sara K. Lindén, Jakob D. Wikstrom
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 14331 (2023)
The mucus layer covering the skin of fish has several roles, including protection against pathogens and mechanical damage. While the mucus layers of various bony fish species have been investigated, the composition and glycan profiles of shark skin m
Externí odkaz:
https://doaj.org/article/8ee9ec609b2445e3861e128609c2a64c