Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jakob Cervin"'
Autor:
Samuel Alsén, Jakob Cervin, Yaxiong Deng, Louis Szeponik, Ulf Alexander Wenzel, Joakim Karlsson, Helena Cucak, Megan Livingston, David Bryder, Qianjin Lu, Bengt Johansson-Lindbom, Ulf Yrlid
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
B cells interact with T follicular helper (Tfh) cells in germinal centers (GCs) to generate high-affinity antibodies. Much less is known about how cognate T–B-cell interactions influence Th cells that enter circulation and peripheral tissues. There
Externí odkaz:
https://doaj.org/article/4d799bf2f9044fdbb729db3bcd5cb042
Autor:
Rathan Joy Komban, Anneli Strömberg, Adi Biram, Jakob Cervin, Cristina Lebrero-Fernández, Neil Mabbott, Ulf Yrlid, Ziv Shulman, Mats Bemark, Nils Lycke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Gut lumen antigens must be continuously sampled by the immune system to maintain proper immune homeostasis. Here the authors show that activated CCR6+CCR1+GL7- gut B cells retrieve lumen antigens from specialized M cells and transfer them across the
Externí odkaz:
https://doaj.org/article/dfa3b986a6dc4e698df2c098d4517404
Autor:
Jakob Cervin, Amberlyn M Wands, Anna Casselbrant, Han Wu, Soumya Krishnamurthy, Aleksander Cvjetkovic, Johanna Estelius, Benjamin Dedic, Anirudh Sethi, Kerri-Lee Wallom, Rebecca Riise, Malin Bäckström, Ville Wallenius, Frances M Platt, Michael Lebens, Susann Teneberg, Lars Fändriks, Jennifer J Kohler, Ulf Yrlid
Publikováno v:
PLoS Pathogens, Vol 14, Iss 2, p e1006862 (2018)
Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors via its B subunit (CTB). We have recently shown that in addition to the previously described binding partner ganglioside GM1, CTB binds to fucosylated proteins.
Externí odkaz:
https://doaj.org/article/f798db5d3c714c6f9abd3318d6d329e7
Autor:
Amberlyn M Wands, Akiko Fujita, Janet E McCombs, Jakob Cervin, Benjamin Dedic, Andrea C Rodriguez, Nicole Nischan, Michelle R Bond, Marcel Mettlen, David C Trudgian, Andrew Lemoff, Marianne Quiding-Järbrink, Bengt Gustavsson, Catharina Steentoft, Henrik Clausen, Hamid Mirzaei, Susann Teneberg, Ulf Yrlid, Jennifer J Kohler
Publikováno v:
eLife, Vol 4 (2015)
Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors using its B subunit (CTB). The ganglioside (glycolipid) GM1 is thought to be the sole CT receptor; however, the mechanism by which CTB binding to GM1 mediates i
Externí odkaz:
https://doaj.org/article/3c68ba7482ae44199ba3d13b04350700
Autor:
Per Björklund, Jakob Cervin, Lynda Mottram, Gyusaang Youn, Nicole S. Sampson, Ulf Yrlid, Andrew Boucher, Ville Wallenius
Publikováno v:
ACS Infectious Diseases
A promising strategy to limit cholera severity involves blockers mimicking the canonical cholera toxin ligand (CT) ganglioside GM1. However, to date the efficacies of most of these blockers have been evaluated in noncellular systems that lack ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ee8d9395eb24e4c391aa070f8ec49b
http://europepmc.org/articles/PMC7227030
http://europepmc.org/articles/PMC7227030
Autor:
Samuel, Alsén, Jakob, Cervin, Yaxiong, Deng, Louis, Szeponik, Ulf Alexander, Wenzel, Joakim, Karlsson, Helena, Cucak, Megan, Livingston, David, Bryder, Qianjin, Lu, Bengt, Johansson-Lindbom, Ulf, Yrlid
Publikováno v:
Frontiers in immunology. 13
B cells interact with T follicular helper (Tfh) cells in germinal centers (GCs) to generate high-affinity antibodies. Much less is known about how cognate T-B-cell interactions influence Th cells that enter circulation and peripheral tissues. Therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70f3dd333cccfce008f3769906a8a691
https://pubmed.ncbi.nlm.nih.gov/35355990
https://pubmed.ncbi.nlm.nih.gov/35355990
Publikováno v:
Biomacromolecules
The canonical binding site on the B subunit of cholera toxin (CTB) binds to GM1 gangliosides on host cells. However, the recently discovered noncanonical binding site on CTB with affinity for fucosylated molecules has raised the possibility that both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33f4ec0b93328fd8f3a86e445f12650
https://pubmed.ncbi.nlm.nih.gov/32960582
https://pubmed.ncbi.nlm.nih.gov/32960582
Autor:
Maria Matson Dzebo, Ulf Yrlid, Amberlyn M. Wands, Gyusaang Youn, Clay S. Bennett, Pernilla Wittung-Stafshede, Nicole S. Sampson, He Huang, Ye Zhang, Chad A. Brautigam, Ville Wallenius, Jakob Cervin, Danielle K. Bright, Jennifer J. Kohler, Per Björklund
Cholera toxin (CT) enters host intestinal epithelia cells, and its retrograde transport to the cytosol results in the massive loss of fluids and electrolytes associated with severe dehydration. To initiate this intoxication process, the B subunit of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35717bd33080eb7c348274995d84c087
https://europepmc.org/articles/PMC5948155/
https://europepmc.org/articles/PMC5948155/
Autor:
Catharina Steentoft, Andrew Lemoff, David C. Trudgian, Bengt Gustavsson, Ulf Yrlid, Benjamin Dedic, Michelle R. Bond, Jennifer J. Kohler, Amberlyn M. Wands, Marcel Mettlen, Akiko Fujita, Susann Teneberg, Jakob Cervin, Janet E. McCombs, Hamid Mirzaei, Henrik Clausen, Nicole Nischan, Marianne Quiding-Järbrink, Andrea C. Rodriguez
Publikováno v:
eLife
eLife, Vol 4 (2015)
eLife, Vol 4 (2015)
Cholera toxin (CT) enters and intoxicates host cells after binding cell surface receptors using its B subunit (CTB). The ganglioside (glycolipid) GM1 is thought to be the sole CT receptor; however, the mechanism by which CTB binding to GM1 mediates i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b150ec9f6cb1a5baddb6832a921596
https://doi.org/10.7554/elife.09545
https://doi.org/10.7554/elife.09545