Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Jakob Hedegaard"'
Autor:
Line Dahl Jeppesen, Lotte Hatt, Ripudaman Singh, Palle Schelde, Katarina Ravn, Christian Liebst Toft, Maria Bach Laursen, Jakob Hedegaard, Inga Baasch Christensen, Bolette Hestbek Nicolaisen, Lotte Andreasen, Lars Henning Pedersen, Ida Vogel, Dorte Launholt Lildballe
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Circulating fetal cells isolated from maternal blood can be used for prenatal testing, representing a safe alternative to invasive testing. The present study investigated the potential of cell-based noninvasive prenatal testing (NIPT) f
Externí odkaz:
https://doaj.org/article/1de434c9e29148f39b2d71fd2aed3f72
Autor:
Anna Katharina Seitz, Lise Lotte Christensen, Emil Christensen, Kasper Faarkrog, Marie Stampe Ostenfeld, Jakob Hedegaard, Iver Nordentoft, Morten Muhlig Nielsen, Johan Palmfeldt, Michelle Thomson, Michael Theis Solgaard Jensen, Roman Nawroth, Tobias Maurer, Torben Falck Ørntoft, Jørgen Bjerggaard Jensen, Christian Kroun Damgaard, Lars Dyrskjøt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Aberrant expression of long non-coding RNAs (lncRNAs) has been regarded as a critical component in bladder cancer (BC) and lncRNAs have been associated with BC development and progression although their overall expression and functional sign
Externí odkaz:
https://doaj.org/article/d1bf7670985049f9b07d1d977c912484
Autor:
Lars Dyrskjøt, Torben F. Ørntoft, Jakob Skou Pedersen, Søren Høyer, Jørgen Bjerggaard Jensen, Michael Borre, Jakob Hedegaard, Søren Vang, Palle Villesen, Mathilde Borg Houlberg Thomsen, Karin Birkenkamp-Demtröder, Iver Nordentoft, Philippe Lamy
Mutations included in the 1530 amplicons target panel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a605cc8cce7e8b9fdb74fea49839889a
https://doi.org/10.1158/0008-5472.22413740
https://doi.org/10.1158/0008-5472.22413740
Autor:
Lars Dyrskjøt, Torben F. Ørntoft, Jakob Skou Pedersen, Søren Høyer, Jørgen Bjerggaard Jensen, Michael Borre, Jakob Hedegaard, Søren Vang, Palle Villesen, Mathilde Borg Houlberg Thomsen, Karin Birkenkamp-Demtröder, Iver Nordentoft, Philippe Lamy
Legend for Supplementary Tables S1-S6 and Supplementary Figures S1-S19.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60bd67dd5a02a0064ba7a5845f53d97c
https://doi.org/10.1158/0008-5472.22413734
https://doi.org/10.1158/0008-5472.22413734
Autor:
Lars Dyrskjøt, Torben F. Ørntoft, Jakob Skou Pedersen, Søren Høyer, Jørgen Bjerggaard Jensen, Michael Borre, Jakob Hedegaard, Søren Vang, Palle Villesen, Mathilde Borg Houlberg Thomsen, Karin Birkenkamp-Demtröder, Iver Nordentoft, Philippe Lamy
Greater knowledge concerning tumor heterogeneity and clonality is needed to determine the impact of targeted treatment in the setting of bladder cancer. In this study, we performed whole-exome, transcriptome, and deep-focused sequencing of metachrono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35174964cb987a99c977cd759a020b47
https://doi.org/10.1158/0008-5472.c.6508802.v1
https://doi.org/10.1158/0008-5472.c.6508802.v1
Autor:
Lars Dyrskjøt, Torben F. Ørntoft, Jakob Skou Pedersen, Søren Høyer, Jørgen Bjerggaard Jensen, Michael Borre, Jakob Hedegaard, Søren Vang, Palle Villesen, Mathilde Borg Houlberg Thomsen, Karin Birkenkamp-Demtröder, Iver Nordentoft, Philippe Lamy
Description of additional methods and procedures used in the study. Also includes Supplementary References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a148adbb9b7e888808b5a98661b0f11
https://doi.org/10.1158/0008-5472.22413755.v1
https://doi.org/10.1158/0008-5472.22413755.v1
Autor:
Line Dahl Jeppesen, Dorte Launholt Lildballe, Lotte Hatt, Jakob Hedegaard, Ripudaman Singh, Christian Liebst Frisk Toft, Palle Schelde, Anders Sune Pedersen, Michael Knudsen, Ida Vogel
Publikováno v:
Jeppesen, L D, Lildballe, D L, Hatt, L, Hedegaard, J, Singh, R, Toft, C L F, Schelde, P, Pedersen, A S, Knudsen, M & Vogel, I 2023, ' Noninvasive prenatal screening for cystic fibrosis using circulating trophoblasts : Detection of the 50 most common disease-causing variants ', Prenatal Diagnosis, vol. 43, no. 1, pp. 3-13 . https://doi.org/10.1002/pd.6276
OBJECTIVES: Cystic fibrosis (CF) is one of the most common severe autosomal recessive disorders. Prenatal or preconception CF screening is offered in some countries. A maternal blood sample in early pregnancy can provide circulating trophoblasts and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c69e4474a5ec00a55d1968248f3fff
https://vbn.aau.dk/ws/files/510206222/Jeppesen_et_al_2023_Noninvasive_prenatal_screening_for_cystic_fibrosis_using_circulating_trophoblasts.pdf
https://vbn.aau.dk/ws/files/510206222/Jeppesen_et_al_2023_Noninvasive_prenatal_screening_for_cystic_fibrosis_using_circulating_trophoblasts.pdf
Autor:
Iver Nordentoft, Philippe Lamy, Karin Birkenkamp-Demtröder, Karey Shumansky, Søren Vang, Henrik Hornshøj, Malene Juul, Palle Villesen, Jakob Hedegaard, Andrew Roth, Kasper Thorsen, Søren Høyer, Michael Borre, Thomas Reinert, Niels Fristrup, Lars Dyrskjøt, Sohrab Shah, Jakob Skou Pedersen, Torben F. Ørntoft
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1649-1663 (2014)
Bladder cancer (or urothelial cell carcinoma [UCC]) is characterized by field disease (malignant alterations in surrounding mucosa) and frequent recurrences. Whole-genome, exome, and transcriptome sequencing of 38 tumors, including four metachronous
Externí odkaz:
https://doaj.org/article/09619361b971482e93771f393be92b0a
Autor:
Jakob Hedegaard, Kasper Thorsen, Mette Katrine Lund, Anne-Mette K Hein, Stephen Jacques Hamilton-Dutoit, Søren Vang, Iver Nordentoft, Karin Birkenkamp-Demtröder, Mogens Kruhøffer, Henrik Hager, Bjarne Knudsen, Claus Lindbjerg Andersen, Karina Dalsgaard Sørensen, Jakob Skou Pedersen, Torben Falck Ørntoft, Lars Dyrskjøt
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98187 (2014)
Formalin-fixed, paraffin-embedded (FFPE) tissues are an invaluable resource for clinical research. However, nucleic acids extracted from FFPE tissues are fragmented and chemically modified making them challenging to use in molecular studies. We analy
Externí odkaz:
https://doaj.org/article/41d99fce8e504708bd2925e3502cfe16
Autor:
Jakob Skou Pedersen, Henrik Hornshøj, Morten Muhlig Nielsen, Claus Højbjerg Gravholt, Iver Nordentoft, Jakob Hedegaard, Anne Skakkebæk, Søren Vang, Christian Trolle
Publikováno v:
Nielsen, M M, Trolle, C, Vang, S, Hornshøj, H, Skakkebaek, A, Hedegaard, J, Nordentoft, I, Pedersen, J S & Gravholt, C H 2020, ' Epigenetic and transcriptomic consequences of excess X-chromosome material in 47,XXX syndrome-A comparison with Turner syndrome and 46,XX females ', American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, vol. 184, no. 2, pp. 279-293 . https://doi.org/10.1002/ajmg.c.31799
47,XXX (triple X) and Turner syndrome (45,X) are sex chromosomal abnormalities with detrimental effects on health with increased mortality and morbidity. In karyotypical normal females, X-chromosome inactivation balances gene expression between sexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579941b0293ea16a6e8ce4224793ea31
https://pure.au.dk/portal/da/publications/epigenetic-and-transcriptomic-consequences-of-excess-xchromosome-material-in-47xxx-syndromea-comparison-with-turner-syndrome-and-46xx-females(6205030a-4daa-4307-b437-dc399dcbd094).html
https://pure.au.dk/portal/da/publications/epigenetic-and-transcriptomic-consequences-of-excess-xchromosome-material-in-47xxx-syndromea-comparison-with-turner-syndrome-and-46xx-females(6205030a-4daa-4307-b437-dc399dcbd094).html