Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jakob, Bouton"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2822-2828 (2018)
Interfering with bacterial cell-to-cell communication is a promising strategy to combat antimicrobial resistance. The natural product hamamelitannin and several of its analogues have been identified as quorum sensing inhibitors. In this paper the syn
Externí odkaz:
https://doaj.org/article/8310797a339546739b2ab7ca04ba47d6
Autor:
Jakob, Bouton, Ludmila, Ferreira de Almeida Fiuza, Camila, Cardoso Santos, Maria Angela, Mazzarella, Maria de Nazaré Correia, Soeiro, Louis, Maes, Izet, Karalic, Guy, Caljon, Serge, Van Calenbergh
Publikováno v:
Journal of medicinal chemistry. 64(7)
Chagas disease and visceral leishmaniasis are two neglected tropical diseases responsible for numerous deaths around the world. For both, current treatments are largely inadequate, resulting in a continued need for new drug discovery. As both kinetop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7976eeb282d3cbf02788632b336476be
https://pubmed.ncbi.nlm.nih.gov/33784107
https://pubmed.ncbi.nlm.nih.gov/33784107
Autor:
Ludmila Ferreira de Almeida Fiuza, Cai Lin, Camila Cardoso Santos, Jakob Bouton, Guy Caljon, Serge Van Calenbergh, Maria de Nazaré Correia Soeiro, Louis Maes, Fabian Hulpia, Otacilio C. Moreira, Izet Karalic, Daniela Ferreira Nunes
Publikováno v:
ChemMedChem
Chagas disease is a tropical infectious disease resulting in progressive organ-damage and currently lacks efficient treatment and vaccine options. The causative pathogen, Trypanosoma cruzi, requires uptake and processing of preformed purines from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79e1e9661ab58e87a9b003924809a29
https://pubmed.ncbi.nlm.nih.gov/33856742
https://pubmed.ncbi.nlm.nih.gov/33856742
Publikováno v:
European journal of medicinal chemistry
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
The kinetoplastid parasites Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. are the causative agents of neglected tropical diseases with a serious burden in several parts of the world. These parasites are incapable of synthesizing purines d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bba1bf295697fe68d176df805a49c47
https://hdl.handle.net/10067/1781760151162165141
https://hdl.handle.net/10067/1781760151162165141
Autor:
Jakob Bouton, Louis Maes, Arno Furquim d’Almeida, Serge Van Calenbergh, Fabian Hulpia, Guy Caljon
Publikováno v:
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
European journal of medicinal chemistry
European journal of medicinal chemistry
Kinetoplastid parasites are the causative agents of neglected tropical diseases with an unmet medical need. These parasites are unable to synthesize the purine ring de novo, and therefore rely on purine salvage to meet their purine demand. Evaluating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e267c781b8ee8aab16aee3a8bccb246
https://hdl.handle.net/1854/LU-8713705
https://hdl.handle.net/1854/LU-8713705
Autor:
Maria Angela Mazzarella, Camila Cardoso Santos, Serge Van Calenbergh, Maria de Nazaré Correia Soeiro, Izet Karalic, Guy Caljon, Louis Maes, Jakob Bouton, Ludmila Ferreira de Almeida Fiuza
Publikováno v:
Journal of medicinal chemistry
Chagas disease and visceral leishmaniasis are two neglected tropical diseases responsible for numerous deaths around the world. For both, current treatments are largely inadequate, resulting in a continued need for new drug discovery. As both kinetop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb46dcee8897f9727b0c27b58b1796eb
Publikováno v:
Organic letters. 22(23)
The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08dd86fb36598af81741693ffba71685
https://pubmed.ncbi.nlm.nih.gov/33210930
https://pubmed.ncbi.nlm.nih.gov/33210930
Autor:
Serge Van Calenbergh, Guy Caljon, Ibrahim A. Alfayez, Dorien Mabille, Gustavo D. Campagnaro, Jakob Bouton, Harry P. de Koning, Fabian Hulpia, Louis Maes
Publikováno v:
European journal of medicinal chemistry
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
African trypanosomiasis, a deadly infectious disease caused by the protozoan Trypanosoma brucei spp., is spread to new hosts by bites of infected tsetse flies. Currently approved therapies all have their specific drawbacks, prompting a search for nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2008e19c54fe71b96394a8322bd15613
https://repository.uantwerpen.be/docstore/d:irua:1098
https://repository.uantwerpen.be/docstore/d:irua:1098
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 2822-2828 (2018)
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Interfering with bacterial cell-to-cell communication is a promising strategy to combat antimicrobial resistance. The natural product hamamelitannin and several of its analogues have been identified as quorum sensing inhibitors. In this paper the syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f2b4a18b476f6ebfd19e12728051bd
https://doaj.org/article/8310797a339546739b2ab7ca04ba47d6
https://doaj.org/article/8310797a339546739b2ab7ca04ba47d6
Publikováno v:
Tetrahedron
TETRAHEDRON
TETRAHEDRON
Azanucleosides, sugar-modified nucleoside analogues containing a 4′ nitrogen atom, have shown a lot of therapeutic potential, e.g. as anti-cancer and antiviral agents. We report the synthesis of a series of 2’-homoazanucleosides, in which the nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4f7096c6c4d8bba6919d54edd115be
https://doi.org/10.1016/j.tet.2017.05.083
https://doi.org/10.1016/j.tet.2017.05.083