Five days of bed rest in young and old adults: Retainment of skeletal muscle mass with neuromuscular electrical stimulation

Autor: Sofie K. Hansen, Pernille Hansen, Hanne Nygaard, Hans D. Grønbæk, Tania W. Berry, Camilla M. Olsen, Per Aagaard, Lars G. Hvid, Jakob Agergaard, Flemming Dela, Charlotte Suetta

Publikováno v: Physiological Reports, Vol 12, Iss 16, Pp n/a-n/a (2024)

Abstract The consequences of short‐term disuse are well known, but effective countermeasures remain elusive. This study investigated the effects of neuromuscular electrical stimulation (NMES) during 5 days of bed rest on retaining lower limb muscle

Externí odkaz: https://doaj.org/article/99db7582b074407ab19cc5c943465e66

Low-load blood flow-restricted resistance exercise produces fiber type-independent hypertrophy and improves muscle functional capacity in older individuals

Autor: Jakob Wang, Anna-Maria Godsk Mogensen, Frederik Thybo, Magnus Brandbyge, Jonas Brorson, Gerrit van Hall, Jakob Agergaard, Frank Vincenzo de Paoli, Benjamin F. Miller, Hans Erik Bøtker, Jean Farup, Kristian Vissing

Publikováno v: Wang, J, Mogensen, A-M G, Thybo, F, Brandbyge, M, Jensen, J B, van Hall, G, Agergaard, J, de Paoli, F V, Miller, B F, Bøtker, H E, Farup, J & Vissing, K 2023, ' Low-load blood flow-restricted resistance exercise produces fiber type-independent hypertrophy and improves muscle functional capacity in older individuals ', Journal of applied physiology (Bethesda, Md. : 1985), vol. 134, no. 4, pp. 1047-1062 . https://doi.org/10.1152/japplphysiol.00789.2022

Low-load blood flow-restricted resistance exercise (BFRRE) constitutes an effective means to produce skeletal muscle hypertrophy. Nonetheless, its applicability to counteract the age-related skeletal muscle decay at a cellular level, is not clear. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e801e75d3772e607e152f4e238579c
https://doi.org/10.1152/japplphysiol.00789.2022

Impaired skeletal muscle hypertrophy signaling and amino acid deprivation response in Apoe knockout mice with an unhealthy lipoprotein distribution

Autor: Peter Schjerling, Grith Højfeldt, Witold Kot, Lars Holm, Jakob Agergaard, Gerrit van Hall, Josué L. Castro-Mejía, Dennis Sandris Nielsen, Mie Cecilie Faber Zillmer, Kenneth Mertz

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Agergaard, J, Zillmer, M C F, Castro-Mejía, J L, Mertz, K, Kot, W, Højfeldt, G, van Hall, G, Nielsen, D S, Schjerling, P & Holm, L 2021, ' Impaired skeletal muscle hypertrophy signaling and amino acid deprivation response in Apoe knockout mice with an unhealthy lipoprotein distribution ', Scientific Reports, vol. 11, 16423 . https://doi.org/10.1038/s41598-021-96000-8

This study explores if unhealthy lipoprotein distribution (LPD) impairs the anabolic and amino acid sensing responses to whey-protein feeding. Thus, if impairment of such anabolic response to protein consumption is seen by the LPD this may negatively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a86f9a39f8d51d3dc3386d6b467599a
https://doaj.org/article/a6c45fb3112845e6ad3da6e163c13379

Postprandial amino acid availability after intake of intact or hydrolyzed meat protein in a mixed meal in healthy elderly subjects: a randomized, single blind crossover trial

Autor: Lars Holm, Jakob Agergaard, Erik T Hansen, Gerrit van Hall

Publikováno v: Amino Acids. 53:951-959

The absorption of dietary proteins affects the anabolic response, among others protein synthesis. For elderly, optimal amino acid absorption is warranted to preserve the amino acid pool of the body, especially skeletal muscle proteins. Therefore, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98b599e6cc9e80a286d7a6051c5607db
https://doi.org/10.1007/s00726-021-03000-z

Comparing Even with Skewed Dietary Protein Distribution Shows No Difference in Muscle Protein Synthesis or Amino Acid Utilization in Healthy Older Individuals: A Randomized Controlled Trial

Autor: Thomas Ehlig Hjermind Justesen, Simon Elmer Jespersen, Thomas Tagmose Thomsen, Lars Holm, Gerrit van Hall, Jakob Agergaard

Publikováno v: Nutrients; Volume 14; Issue 21; Pages: 4442

Sarcopenia is a multifactorial disease that limits autonomy for the growing elderly population. An optimal amount of dietary protein has shown to be important to maintain muscle mass during aging. Yet, the optimal distribution of that dietary protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baa3e08c02add18637d5074a3b578284
https://doi.org/10.3390/nu14214442